Ligne de temps

25 août 2018
patent

Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri

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01 nov. 2016
publication

Heparan sulfate differentially controls CXCL12α- and CXCL12γ-mediated cell migration through differential presentation to their receptor CXCR4

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10 oct. 2016
publication

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge

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01 août 2014
publication

Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels

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28 juin 2013
publication

Mucin-like peptides from Echinococcus granulosus induce antitumor activity

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03 oct. 2012
publication

Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions

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04 juin 2012
publication

CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension

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16 mars 2012
publication

Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain

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27 janv. 2012
publication

A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage

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23 juil. 2011
publication

Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO

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15 avr. 2011
publication

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

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01 févr. 2010
publication

Slightly modifying pseudoproline dipeptides incorporation strategy enables solid phase synthesis of a 54 AA fragment of caveolin-1 encompassing the intramembrane domain

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06 sept. 2009
publication

A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry

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28 août 2009
publication

Glycosaminoglycan mimetics inhibit SDF-1/CXCL12-mediated migration and invasion of human hepatoma cells

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17 août 2009
publication

Glycosaminoglycans and syndecan-4 are involved in SDF-1/CXCL12-mediated invasion of human epitheloid carcinoma HeLa cells

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20 avr. 2009
publication

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling

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16 sept. 2008
publication

Sulfated oligosaccharides (heparin and fucoidan) binding and dimerization of stromal cell-derived factor-1 (SDF-1/CXCL 12) are coupled as evidenced by affinity CE-MS analysis

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02 juil. 2008
publication

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins

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13 juin 2008
publication

Small neutralizing molecules to inhibit actions of the chemokine CXCL12

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24 avr. 2008
publication

CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome

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19 mars 2008
publication

Polypyrrole oligosaccharide array and surface plasmon resonance imaging for the measurement of glycosaminoglycan binding interactions

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01 mars 2008
publication

Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling

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14 nov. 2007
publication

An ectromelia virus protein that interacts with chemokines through their glycosaminoglycan binding domain

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31 oct. 2007
publication

The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4

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01 sept. 2007
publication

Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO

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15 juil. 2005
publication

Single-spanning membrane protein insertion in membrane mimetic systems: role and localization of aromatic residues

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10 avr. 2005
publication

The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro

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18 févr. 2005
publication

Synthesis of two linear PADRE conjugates bearing a deca- or pentadecasaccharide B epitope as potential synthetic vaccines against Shigella flexneri serotype 2a infection

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15 déc. 2004
publication

CXCR4-tropic HIV-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary CD4+ T lymphocytes

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09 nov. 2004
publication

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

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20 sept. 2004
publication

Elastase release by transmigrating neutrophils deactivates endothelial-bound SDF-1alpha and attenuates subsequent T lymphocyte transendothelial migration

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02 août 2004
publication

Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV

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26 avr. 2004
publication

Preparation of synthetic glycoconjugates as potential vaccines against Shigella flexneri serotype 2a disease

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01 avr. 2004
publication

Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities

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15 mars 2003
publication

Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus

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22 nov. 2002
publication

Low levels of co-receptor CCR5 are sufficient to permit HIV envelope-mediated fusion with resting CD4 T cells

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19 nov. 2002
publication

Deciphering the role of individual acyl chains in the interaction network between phosphatidylserines and a single-spanning membrane protein

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01 oct. 2002
publication

Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure

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26 févr. 2002
publication

Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4

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15 janv. 2002
publication

Interleukin-10 modulates the sensitivity of peritoneal B lymphocytes to chemokines with opposite effects on stromal cell-derived factor-1 and B-lymphocyte chemoattractant

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21 août 2001
publication

Concerted influence of key amino acids on the lipid binding properties of a single-spanning membrane protein: NMR and mutational analysis

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14 mai 2001
publication

Optimal inhibition of X4 HIV isolates by the CXC chemokine stromal cell-derived factor 1 alpha requires interaction with cell surface heparan sulfate proteoglycans

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01 févr. 2001
publication

Production of stromal cell-derived factor 1 by mesothelial cells and effects of this chemokine on peritoneal B lymphocytes

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21 nov. 2000
publication

Characterization of the stromal cell-derived factor-1alpha-heparin complex

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01 nov. 2000
publication

Mimicking a conformational B cell epitope of the heat shock protein PfHsp70-1 antigen of Plasmodium falciparum using a multiple antigenic peptide

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01 sept. 2000
publication

SDF-1-induced activation of ERK enhances HIV-1 expression

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21 août 2000
publication

Subsecond induction of alpha4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions

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01 août 2000
publication

Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes

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01 janv. 2000
publication

Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes

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01 déc. 1999
publication

Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein

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20 août 1999
publication

Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine

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01 juil. 1998
publication

A conformational equilibrium in a protein fragment caused by two consecutive capping boxes: 1H-, 13C-NMR, and mutational analysis

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26 juin 1998
publication

Exploring the folding pathways of annexin I, a multidomain protein. I. non-native structures stabilize the partially folded state of the isolated domain 2 of annexin I

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17 avr. 1998
publication

Genomic organization and promoter characterization of human CXCR4 gene

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01 mars 1998
publication

Human immunodeficiency virus (HIV) envelope binds to CXCR4 independently of CD4, and binding can be enhanced by interaction with soluble CD4 or by HIV envelope deglycosylation

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01 févr. 1998
publication

Does a peptide bound to a monoclonal antibody always adopt a unique conformation?

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01 janv. 1998
publication

Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype

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26 nov. 1996
publication

NMR conformational study of the cytoplasmic domain of the canine Sec61 gamma protein from the protein translocation pore of the endoplasmic reticulum membrane

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13 août 1996
publication

Folding properties of an annexin I domain: a 1H-15N NMR and CD study

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01 juin 1996
publication

Identification of lysine residues required for signal-induced ubiquitination and degradation of I kappa B-alpha in vivo

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01 mai 1996
publication

Permanent occupancy of the human immunodeficiency virus type 1 enhancer by NF-kappa B is needed for persistent viral replication in monocytes

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29 mars 1996
publication

Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo

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01 oct. 1995
publication

Nonnative capping structure initiates helix folding in an annexin I fragment. A 1H NMR conformational study

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01 oct. 1995
publication

Chemical structure and translation inhibition studies of the antibiotic microcin C7

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29 avr. 1995
publication

Nascent chains: folding and chaperone interaction during elongation on ribosomes

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01 mars 1995
publication

Importance of residues 2-9 in the immunoreactivity, subunit interactions, and activity of the beta 2 subunit of Escherichia coli tryptophan synthase

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20 juil. 1993
publication

Proton NMR conformational study of an annexin I fragment: influence of a phospholipidic micellar environment

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01 juil. 1992
publication

Novel version of Multiple Antigenic Peptide allowing incorporation on a cysteine functionalized lysine tree

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10 mars 1992
publication

Peptide secondary structure induced by a micellar phospholipidic interface: proton NMR conformational study of a lipopeptide

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01 févr. 1992
publication

1H-NMR conformational study of a synthetic peptide derived from the consensus sequence of annexins

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01 nov. 1991
publication

1H-NMR conformational analysis of a high-affinity antigenic 11-residue peptide from the tryptophan synthase beta 2 subunit

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01 avr. 1991
publication

Peptide/antibody recognition: synthetic peptides derived from the E. coli tryptophan synthase beta 2 subunit interact with high affinity with an anti-beta 2 monoclonal antibody

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01 déc. 1989
publication

Reaction of staphylococcal alpha-toxin with peptide-induced antibodies

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01 oct. 1989
publication

A new cell surface molecule closely related to mouse class I transplantation antigens

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01 mai 1977
publication

[Injuries and diseases of the diaphragm]

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