Ligne de temps
Ludovic Deriano
Responsable de Structure
30 juin 2023
17 mai 2023
28 juin 2022
publication
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.
Lire plus07 mars 2022
11 janv. 2022
news
New publication – The Sec61 translocon is a therapeutic vulnerability in multiple myeloma
Lire plus05 janv. 2022
publication
The (Lack of) DNA Double-Strand Break Repair Pathway Choice During V(D)J Recombination
Lire plus24 nov. 2021
14 sept. 2021
04 mai 2021
09 nov. 2020
news
Repair of G1 induced DNA double-strand breaks in S-G2/ breaks in S-G2/M by alternative NHEJ.
Lire plus05 nov. 2020
project
Study of DNA double-strand break repair regulation in B cells – implication for cancer therapy
Lire plus16 oct. 2020
05 déc. 2019
04 juin 2019
publication
Breakage-fusion-bridge events trigger complex genome rearrangements and amplifications in developmentally arrested T cell lymphomas
Lire plus17 avr. 2019
publication
Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function
Lire plus22 mars 2019
14 févr. 2019
23 nov. 2018
23 nov. 2018
20 août 2018
publication
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Lire plus27 juil. 2018
publication
Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells
Lire plus04 sept. 2017
publication
Generation and CRISPR/Cas9 editing of transformed progenitor B cells as a pseudo-physiological system to study DNA repair gene function in V(D)J recombination
Lire plus14 juin 2017
publication
[Paralogy and redundancy: maintaining genome integrity during V(D)J recombination]
Lire plus15 févr. 2017
15 nov. 2016
01 nov. 2016
01 oct. 2016
28 sept. 2016
02 sept. 2016
26 juil. 2016
22 juin 2016
31 mars 2016
event
Recurrently Breaking Genes in Brain Progenitor Cells may Contribute to Diversity and Disease
Lire plus02 févr. 2016
publication
RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair
Lire plus07 sept. 2015
01 juil. 2015
01 juil. 2015
11 mai 2015
23 oct. 2014
20 avr. 2014
publication
RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of ‘alternative NHEJ’
Lire plus11 sept. 2013
publication
Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage
Lire plus29 août 2013
publication
RAG2’s acidic hinge restricts repair-pathway choice and promotes genomic stability
Lire plus14 févr. 2013
publication
Higher-order looping and nuclear organization of Tcra facilitate targeted rag cleavage and regulated rearrangement in recombination centers
Lire plus01 janv. 2013
publication
The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage
Lire plus29 oct. 2012
publication
A streamlined method for detecting structural variants in cancer genomes by short read paired-end sequencing
Lire plus01 mars 2011
10 avr. 2009
publication
Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates
Lire plus17 nov. 2008
publication
Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability
Lire plus27 sept. 2007
15 déc. 2006
publication
Chronic exposure to sublethal doses of radiation mimetic Zeocin selects for clones deficient in homologous recombination
Lire plus01 juin 2006
publication
Mutagenicity of non-homologous end joining DNA repair in a resistant subset of human chronic lymphocytic leukaemia B cells
Lire plus01 mai 2006
17 févr. 2005
publication
Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway
Lire plus01 août 2003
publication
B-cell chronic lymphocytic leukaemia: a polymorphic family unified by genomic features
Lire plus12 sept. 2001
publication