Ligne de temps
Niels Volkmann
Responsable de Structure
20 déc. 2022
publication
Morphological control enables nanometer-scale dissection of cell-cell signaling complexes.
Lire plus01 déc. 2022
01 nov. 2022
26 oct. 2022
publication
Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality.
Lire plus01 sept. 2022
publication
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells.
Lire plus01 févr. 2022
publication
The complexin C-terminal amphipathic helix stabilizes the fusion pore open state by sculpting membranes.
Lire plus01 déc. 2021
25 mars 2021
publication
The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity.
Lire plus11 sept. 2020
21 mai 2020
publication
Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum.
Lire plus01 nov. 2019
publication
Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies.
Lire plus01 oct. 2019
publication
High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture.
Lire plus04 juin 2019
publication
Biophysical Characterization of a Nanodisc with and without BAX: An Integrative Study Using Molecular Dynamics Simulations and Cryo-EM.
Lire plus01 mai 2019
01 déc. 2018
16 oct. 2018
publication
Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale.
Lire plus01 mars 2018
publication
Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models.
Lire plus01 janv. 2018
publication
Marker-free method for accurate alignment between correlated light, cryo-light, and electron cryo-microscopy data using sample support features.
Lire plus01 janv. 2018
publication
Conformational Equilibrium of Human Platelet Integrin Investigated by Three-Dimensional Electron Cryo-Microscopy.
Lire plus13 nov. 2017
publication
Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos.
Lire plus17 oct. 2017
publication
Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.
Lire plus01 mars 2017
publication
Nano-scale actin-network characterization of fibroblast cells lacking functional Arp2/3 complex.
Lire plus01 oct. 2016
publication
Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry.
Lire plus23 févr. 2016
publication
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human α(IIb)β(3) Integrin Complexes.
Lire plus05 nov. 2015
publication
Orchestration of ErbB3 signaling through heterointeractions and homointeractions.
Lire plus01 oct. 2015
publication
The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
Lire plus01 sept. 2015
publication
Validation methods for low-resolution fitting of atomic structures to electron microscopy data.
Lire plus01 sept. 2015
publication
Efficient Extraction of Macromolecular Complexes from Electron Tomograms Based on Reduced Representation Templates.
Lire plus01 août 2015
publication
Accurate membrane tracing in three-dimensional reconstructions from electron cryotomography data.
Lire plus01 avr. 2015
publication
Cellular chirality arising from the self-organization of the actin cytoskeleton.
Lire plus01 mars 2015
31 oct. 2014
publication
Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force.
Lire plus25 oct. 2014
publication
Three-dimensional reconstructions of actin filaments capped by Arp2/3 complex.
Lire plus01 oct. 2014
publication
Holoenzyme structures of endothelial nitric oxide synthase – an allosteric role for calmodulin in pivoting the FMN domain for electron transfer.
Lire plus01 janv. 2014
01 déc. 2013
publication
αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors.
Lire plus01 nov. 2013
publication
The architectural relationship of components controlling mast cell endocytosis.
Lire plus01 oct. 2013
01 oct. 2013
publication
Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.
Lire plus15 sept. 2012
publication
Toxofilin upregulates the host cortical actin cytoskeleton dynamics, facilitating Toxoplasma invasion.
Lire plus15 août 2012
28 mai 2012
publication
The C-terminal tail domain of metavinculin, vinculin’s splice variant, severs actin filaments.
Lire plus10 févr. 2012
publication
Key structural features of the actin filament Arp2/3 complex branch junction revealed by molecular simulation.
Lire plus01 févr. 2012
publication
Putting structure into context: fitting of atomic models into electron microscopic and electron tomographic reconstructions.
Lire plus04 janv. 2012
publication
Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors.
Lire plus01 janv. 2011
01 juin 2010
publication
Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping.
Lire plus01 juin 2010
01 janv. 2010
publication
Methods for segmentation and interpretation of electron tomographic reconstructions.
Lire plus01 juil. 2009
publication
Confidence intervals for fitting of atomic models into low-resolution densities.
Lire plus01 juin 2008
publication
Three-dimensional architecture of hair-bundle linkages revealed by electron-microscopic tomography.
Lire plus01 juin 2008
publication
Segmentation of electron tomographic data sets using fuzzy set theory principles.
Lire plus10 mars 2008
23 janv. 2008
07 nov. 2007
publication
The R403Q myosin mutation implicated in familial hypertrophic cardiomyopathy causes disorder at the actomyosin interface.
Lire plus24 août 2007
publication
Evidence for an interaction between the SH3 domain and the N-terminal extension of the essential light chain in class II myosins.
Lire plus10 août 2007
01 mai 2007
publication
Efficient automatic noise reduction of electron tomographic reconstructions based on iterative median filtering.
Lire plus01 mai 2007
publication
Density-based score for selecting near-native atomic models of unknown structures.
Lire plus09 mars 2007
publication
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation.
Lire plus01 sept. 2006
publication
Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions.
Lire plus20 janv. 2006
01 nov. 2005
publication
Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions.
Lire plus02 sept. 2005
publication
The structural basis of myosin V processive movement as revealed by electron cryomicroscopy.
Lire plus17 janv. 2005
publication
Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function.
Lire plus25 oct. 2004
25 oct. 2004
publication
An approach to automated particle picking from electron micrographs based on reduced representation templates.
Lire plus22 oct. 2004
13 avr. 2004
publication
Direct continuities between cisternae at different levels of the Golgi complex in glucose-stimulated mouse islet beta cells.
Lire plus01 sept. 2003
publication
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2.
Lire plus18 mars 2003
01 janv. 2003
01 janv. 2003
15 nov. 2002
publication
Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd.
Lire plus25 oct. 2002
publication
A novel three-dimensional variant of the watershed transform for segmentation of electron density maps.
Lire plus29 août 2002