Neuro-Immunologie Virale

Présentation

Désolé, cet article est seulement disponible en Anglais Américain.

Membres

Monique Lafon

Responsable de Structure

Responsable

Edmond Bellance

Aide technique

Christophe Prehaud

Chercheur(euse) Permanent(e)

Marie-Christine Cumont

Clara Bernard

Etudiant(e)

caroline binet

Personnel Administratif

Florian Bakoa

Etudiant(e) en thèse

Saliha Azebi

Ingénieur(e) de Recherche

Anciens Membres

Lucas Bianchi

Thérèse Couderc

Anaelle Da Costa De Matos

Damien Batalie

Ilrae Cho

Corinne Baran

Sandrine Vitry

Catherine Tran

Projets

project

ongoing

4 Membres

Axonal regeneration of rabies virus infected adult mouse sensory neurons

Monique Lafon (PI)

The virulence of a microbe is related to its capacity to invade host tissues and successfully promote its own multiplication and dissemination. Rabies virus, a neurotropic virus that causes fatal encephalitis in mammals, has […]

Projet Transversal

Institut Carnot Pasteur MS

Le label Carnot vise à reconnaître la 
capacité de structures de recherche à collaborer avec des partenaires socio-
économiques, notamment des entreprises, tout en renforçant leur visibilité. Un institut Canot (IC) labélisé bénéficie de moyens […]

Financements

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Publications

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• 2019
  Khan Z, Terrien E, Delhommel F, Lefebvre-Omar C, Bohl D, Vitry S, Bernard C, Ramirez J, Chaffotte A, Ricquier K, Vincentelli R, Buc H, Prehaud C, Wolff N, Lafon M, Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth, J. Biol. Chem. 2019 Sep;294(37):13755-13768.
• 2019
  da Costa A, Prehaud C, Bakoa F, Afonso P, Ceccaldi PE, Lafaye P, Lafon M, A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain, J Vis Exp 2019 Apr;(146).
• 2018
  da Costa A, Prehaud C, Khou C, Pardigon N, Saulnier A, Nougarede N, Lafon M, Innovative in cellulo method as an alternative to in vivo neurovirulence test for the characterization and quality control of human live Yellow Fever virus vaccines: A pilot study, Biologicals 2018 May;53:19-29.
• 2018
  Da Costa A, Prehaud C, Khou C, Pardigon N, Saulnier A, Nougarede N, Lafon M, Innovative in cellulo method as an alternative to in vivo neurovirulence test for the characterization and quality control of human live Yellow Fever virus vaccines: A pilot study., Biologicals. 2018 May;53:19-29. doi: 10.1016/j.biologicals.2018.03.004. Epub 2018 Mar 24.
• 2018
  Phoolcharoen W, Banyard AC, Prehaud C, Selden D, Wu G, Birch CPD, Szeto TH, Lafon M, Fooks AR, Ma JK, In vitro and in vivo evaluation of a single chain antibody fragment generated in planta with potent rabies neutralisation activity, Vaccine 2018 Mar;.
• 2017
  Seo W, Prehaud C, Khan Z, Sabeta C, Lafon M, Investigation of rabies virus glycoprotein carboxyl terminus as an in vitro predictive tool of neurovirulence. A 3R approach, Microbes Infect. 2017 Sep - Oct;19(9-10):476-484.
• 2016
  Mounce BC, Cesaro T, Moratorio G, Hooikaas PJ, Yakovleva A, Werneke SW, Smith EC, Poirier EZ, Simon-Loriere E, Prot M, Tamietti C, Vitry S, Volle R, Khou C, Frenkiel MP, Sakuntabhai A, Delpeyroux F, Pardigon N, Flamand M, Barba-Spaeth G, Lafon M, Denison MR, Albert ML, Vignuzzi M, Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses, J. Virol. 2016 Nov;90(21):9683-9692.
• 2016
  Maisonneuve P, Caillet-Saguy C, Vaney MC, Bibi-Zainab E, Sawyer K, Raynal B, Haouz A, Delepierre M, Lafon M, Cordier F, Wolff N, Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ, J. Biol. Chem. 2016 08;291(32):16699-708.
• 2015
  Caillet-Saguy C, Maisonneuve P, Delhommel F, Terrien E, Babault N, Lafon M, Cordier F, Wolff N, Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus, Prog. Biophys. Mol. Biol. 2015 Oct;119(1):53-9.
• 2014
  Si-Tahar M, Blanc F, Furio L, Chopy D, Balloy V, Lafon M, Chignard M, Fiette L, Langa F, Charneau P, Pothlichet J, Protective role of LGP2 in influenza virus pathogenesis, J. Infect. Dis. 2014 Jul;210(2):214-23.
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Publié le: 11 May 2015 • Modifié le: 01 Aug 2019