Présentation
GDSCTools is a free open-source Python library dedicated to the study of drug responses in the context of the GDSC (Genomics of Drug Sensitivity in Cancer) project. The main developer is `Thomas Cokelaer (Institut Pasteur) `_, and it is a
joint effort of the groups of Mathew Garnett (Sanger Institute) and Julio Saez-Rodriguez (RWTH Aachen & EMBL-EBI)
It contains utilities to find significant associations between drugs and genomic features (e.g., gene mutation) based on an ANOVA analysis. Note, however, that other methods based on e.g., Elastic Net are also available. The GDSCTools library should also be useful in manipulating dedicated data sets such as IC50 or MoBEM (genomic features) data structures.
- Source code: https://github.com/CancerRxGene/gdsctools
- Documentation: gdsctools.readthedocs.io