-
2024Mapping the molecular motions of 5-HT3 serotonin-gated channel by voltage-clamp fluorometry., Elife 2024 Jun; 12(): .
-
2024The Nicotinic Acetylcholine Receptor and its Pentameric Homologs: Toward an Allosteric Mechanism of Signal Transduction at the Atomic Level., Annu Rev Biochem 2024 Feb; (): .
-
2024Short-chain mono-carboxylates as negative modulators of allosteric transitions in Gloeobacter violaceus ligand-gated ion channel, and impact of a pre-β5 strand (Loop Ω) double mutation on crotonate, not butyrate effect., Physiol Rep 2024 Feb; 12(3): e15916.
-
2024A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm., J Biol Chem 2024 Jan; 300(1): 105575.
-
2023An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies., Nat Commun 2023 Sep; 14(1): 5964.
-
2023Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor., Cell Mol Life Sci 2023 May; 80(6): 164.
-
2023Fumarate as positive modulator of allosteric transitions in the pentameric ligand-gated ion channel GLIC: Requirement of an intact vestibular pocket., J Physiol 2023 Apr; (): .
-
2023Illumination of a progressive allosteric mechanism mediating the glycine receptor activation., Nat Commun 2023 Feb; 14(1): 795.
-
2023Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity., Front Mol Biosci 2023 ; 10(): 1192621.
-
2022Design of crotoxin-based peptides with potentiator activity targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator., J Mol Biol 2022 Dec; (): 167929.
-
2022Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains., iScience 2022 Nov; 25(11): 105467.
-
2022Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway., Sci Adv 2022 Oct; 8(41): eadc9340.
-
2022Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins., Front Microbiol 2022 ; 13(): 829094.
-
2022Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7., Front Mol Biosci 2022 ; 9(): 923740.
-
2021Photo-isomerizable tweezers to probe ionotropic receptor mechanisms., Curr Opin Pharmacol 2021 Dec; 62(): 109-116.
-
2021PDZ-Containing Proteins Targeted by the ACE2 Receptor., Viruses 2021 11; 13(11): .
-
2021Mutational analysis to explore long-range allosteric couplings involved in a pentameric channel receptor pre-activation and activation., Elife 2021 Sep; 10(): .
-
2021Host PDZ-containing proteins targeted by SARS-Cov-2., FEBS J 2021 Apr; (): .
-
2021Phylogenetic analysis of Harmonin homology domains., BMC Bioinformatics 2021 Apr; 22(1): 190.
-
2021Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication., Sci Rep 2021 Feb; 11(1): 3266.
-
2021Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors., Cell Mol Life Sci 2021 Feb; 78(3): 1051-1064.
-
2021Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients., Prog Neurobiol 2021 02; 197(): 101898.
-
2021Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein., Sci Rep 2021 Jan; 11(1): 944.
-
2021PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations., Methods Mol Biol 2021 ; 2256(): 89-124.
-
2021Automatic Bayesian Weighting for SAXS Data., Front Mol Biosci 2021 ; 8(): 671011.
-
2020Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis., Proc Natl Acad Sci U S A 2020 12; 117(49): 31278-31289.
-
2020Crystal Structure of Isoform CBd of the Basic Phospholipase A2 Subunit of Crotoxin: Description of the Structural Framework of CB for Interaction with Protein Targets., Molecules 2020 Nov; 25(22): .
-
2020Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners., J Mol Biol 2020 11; 432(22): 5920-5937.
-
2020The desensitization pathway of GABAA receptors, one subunit at a time., Nat Commun 2020 10; 11(1): 5369.
-
2020Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells., Sci Rep 2020 Oct; 10(1): 16430.
-
2020Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate., Proc Natl Acad Sci U S A 2020 08; 117(33): 19963-19969.
-
2020Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study., Structure 2020 07; 28(7): 747-759.e3.
-
2020Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase., PLoS One 2020 ; 15(12): e0244613.
-
2019Identification of protein-protein and ribonucleoprotein complexes containing Hfq., Sci Rep 2019 Oct; 9(1): 14054.
-
2019Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth, J. Biol. Chem. 2019 Sep;294(37):13755-13768.
-
2019Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein., Sci Rep 2019 05; 9(1): 7438.
-
2019Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors, ACS Chem Neurosci 2019 May;10(5):2551-2559.
-
2019High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay, Methods Mol. Biol. 2019;2025:439-476.
-
2018Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel, Proc. Natl. Acad. Sci. U.S.A. 2018 12;115(52):E12172-E12181.
-
2018Conformational transitions of the serotonin 5-HT receptor, Nature 2018 11;563(7730):275-279.
-
2018An Ion-Permeable State of the Glycine Receptor Captured by Molecular Dynamics, Structure 2018 (in press).
-
2018Structural plasticity of the HHD2 domain of whirlin., FEBS J 2018 Oct; 285(20): 3738-3752.
-
2018Structural titration of receptor ion channel GLIC gating by HS-AFM, Proc. Natl. Acad. Sci. U.S.A. 2018 10;115(41):10333-10338.
-
2018X-ray crystal structures of the type IVb secretion system DotB ATPases., Protein Sci. 2018 08; 27(8): 1464-1475.
-
2018The dual-gate model for pentameric ligand-gated ion channels activation and desensitization., J Physiol 2018 05; 596(10): 1873-1902.
-
2018Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation, Proc. Natl. Acad. Sci. U.S.A. 2018 04;115(17):E3959-E3968.
-
2017Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel, PLoS Biol. 2017 12;15(12):e2004470.
-
2017Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors, Sci Rep 2017 Nov;7(1):16606.
-
2017Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites., Nat Struct Mol Biol 2017 Nov; 24(11): 977-985.
-
2017Interfering peptides targeting protein-protein interactions: the next generation of drugs?, Drug Discov. Today 2018 Feb;23(2):272-285.
-
2017Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors, PLoS ONE 2017;12(10):e0186206.
-
2017Privileged Substructures to Modulate Protein-Protein Interactions, J Chem Inf Model 2017 Oct;57(10):2448-2462.
-
2017The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery, Sci Rep 2017 Aug;7(1):9450.
-
2017Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains., Sci Rep 2017 08; 7(1): 7875.
-
2017On the permeation of large organic cations through the pore of ATP-gated P2X receptors, Proc. Natl. Acad. Sci. U.S.A. 2017 May;114(19):E3786-E3795.
-
2017New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8, Protein Sci. 2017 Feb;26(2):343-354.
-
2017The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation., FEBS J 2017 02; 284(4): 602-614.
-
2017Gene Expression and Activity Profiling Reveal a Significant Contribution of Exo-Phosphotransferases to the Extracellular Nucleotides Metabolism in HUVEC Endothelial Cells, J. Cell. Biochem. 2017 Jun;118(6):1341-1348.
-
2016Influence of Mesenchymal Stem Cells Conditioned Media on Proliferation of Urinary Tract Cancer Cell Lines and Their Sensitivity to Ciprofloxacin, J. Cell. Biochem. 2017 Jun;118(6):1361-1368.
-
2016Neurogenic Differentiation of Mesenchymal Stem Cells Induces Alterations in Extracellular Nucleotides Metabolism, J. Cell. Biochem. 2017 Mar;118(3):478-486.
-
2016Interaction of three-finger proteins from snake venoms and from mammalian brain with the cys-loop receptors and their models, Dokl. Biochem. Biophys. 2016 May;468(1):193-6.
-
2016High Quality Independent From a Donor: Human Amniotic Fluid Derived Stem Cells-A Practical Analysis Based on 165 Clinical Cases, J. Cell. Biochem. 2017 Jan;118(1):116-126.
-
2016Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain, J. Clin. Invest. 2016 Jul;126(7):2547-60.
-
2016Canine Adipose-Derived Stem Cells: Purinergic Characterization and Neurogenic Potential for Therapeutic Applications, J. Cell. Biochem. 2017 Jan;118(1):58-65.
-
2016Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ., J Biol Chem 2016 08; 291(32): 16699-708.
-
2016Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis, J. Mol. Biol. 2016 Jul;428(14):2898-915.
-
2016Cloning and biochemical characterization of indole-3-acetic acid-amino acid synthetase PsGH3 from pea, Plant Physiol. Biochem. 2016 Oct;107:9-20.
-
2016Emerging Molecular Mechanisms of Signal Transduction in Pentameric Ligand-Gated Ion Channels, Neuron 2016 05;90(3):452-70.
-
2016Non-native ligands define the active site of Pennisetum glaucum (L.) R. Br dehydroascorbate reductase, Biochem. Biophys. Res. Commun. 2016 05;473(4):1152-1157.
-
2016Imbalance in chemical space: How to facilitate the identification of protein-protein interaction inhibitors, Sci Rep 2016 Apr;6:23815.
-
2016Special Issue on “Toxins: New targets and new functions”, Toxicon 2016 Jun;116:1-3.
-
2016Neurotoxic phospholipase A2 from rattlesnake as a new ligand and new regulator of prokaryotic receptor GLIC (proton-gated ion channel from G. violaceus), Toxicon 2016 Jun;116:63-71.
-
2016[Relationships between venomous function and innate immune function], Biol Aujourdhui 2015;209(3):195-210.
-
2015Chondrogenic Differentiation of Human Mesenchymal Stem Cells Results in Substantial Changes of Ecto-Nucleotides Metabolism, J. Cell. Biochem. 2015 Dec;116(12):2915-23.
-
2015The nicotinic acetylcholine receptor: From molecular biology to cognition., Neuropharmacology 2015 Sep; 96(Pt B): 135-6.
-
2015Cheminformatics Based Machine Learning Models for AMA1-RON2 Abrogators for Inhibiting Plasmodium falciparum Erythrocyte Invasion, Mol Inform 2015 Oct;34(10):655-64.
-
2015Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG., Chem Biol 2015 Jul; 22(7): 917-27.
-
2015Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis., Structure 2015 Jun; 23(6): 1039-48.
-
2015Secretion systems in Gram-negative bacteria: structural and mechanistic insights, Nat. Rev. Microbiol. 2015 Jun;13(6):343-59.
-
2015Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors, Alcohol. Clin. Exp. Res. 2015 Jun;39(6):962-8.
-
2015The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation., Proteins 2015 May; 83(5): 982-8.
-
2015Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus., Prog Biophys Mol Biol 2015 Oct; 119(1): 53-9.
-
2015Cell therapy in Duchenne muscular dystrophy treatment: clinical trials overview, Crit. Rev. Eukaryot. Gene Expr. 2015;25(1):1-11.
-
2014Secondary structure reshuffling modulates glycosyltransferase function at the membrane., Nat Chem Biol 2015 Jan; 11(1): 16-8.
-
2014Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict among conjugative plasmids, Nat Commun 2014 Oct;5:5322.
-
2014Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain., FEBS J 2014 Nov; 281(21): 4852-65.
-
2014The sequential tissue distribution of duck Tembusu virus in adult ducks, Biomed Res Int 2014;2014:703930.
-
2014The vaccine efficacy of recombinant duck enteritis virus expressing secreted E with or without PrM proteins of duck tembusu virus, Vaccine 2014 Sep;32(41):5271-7.
-
2014A unified nomenclature and amino acid numbering for human PTEN., Sci Signal 2014 Jul; 7(332): pe15.
-
2014Chaperones are necessary for the expression of catalytically active potato apyrases in prokaryotic cells, Appl. Biochem. Biotechnol. 2014 Jul;173(6):1349-59.
-
2014Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development., Antiviral Res 2014 May; 105(): 8-16.
-
2014A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)., Biochem J 2014 Feb; 457(3): 425-34.
-
2014The expression of p63 and Ck HMW in magnum and infundibulum of Gallus domesticus oviduct, Folia Biol. (Krakow) 2014;62(3):179-85.
-
2013Intermediate closed state for glycine receptor function revealed by cysteine cross-linking, Proc. Natl. Acad. Sci. U.S.A. 2013 Oct;110(42):17113-8.
-
2013GarA is an essential regulator of metabolism in Mycobacterium tuberculosis., Mol Microbiol 2013 Oct; 90(2): 356-66.
-
2013Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain, EMBO Mol Med 2013 10;5(10):1484-501.
-
2013H7N9 influenza viruses are transmissible in ferrets by respiratory droplet, Science 2013 Jul;341(6144):410-4.
-
2013Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC, J. Med. Chem. 2013 Jun;56(11):4619-30.
-
2013Isolation and bioinformatic analysis of seven genes encoding potato apyrase. Bacterial overexpresssion, refolding and initial kinetic studies on some recombinant potato apyrases, Phytochemistry 2013 Sep;93:8-17.
-
2013Structural sensitivity of a prokaryotic pentameric ligand-gated ion channel to its membrane environment, J. Biol. Chem. 2013 Apr;288(16):11294-303.
-
2013[Prokaryotic expression systems], Postepy Hig Med Dosw (Online) 2013 Mar;67:119-29.
-
2013[Epidermal stem cells–biology and potential applications in regenerative medicine], Postepy Biochem. 2013;59(2):219-27.
-
2012Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines, Proc. Natl. Acad. Sci. U.S.A. 2012 Oct;109(44):E3028-34.
-
2012Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates, Mol. Pharmacol. 2012 Oct;82(4):687-99.
-
2012The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor, Life Sci. 2012 Aug;91(3-4):107-14.
-
2012Role of the iron axial ligands of heme carrier HasA in heme uptake and release., J Biol Chem 2012 Aug; 287(32): 26932-43.
-
2012[In vitro renaturation of proteins from inclusion bodies], Postepy Hig Med Dosw (Online) 2012 Jun;66:322-9.
-
2012Crystallographic characterization of functional sites of crotoxin and ammodytoxin, potent β-neurotoxins from Viperidae venom, Toxicon 2012 Sep;60(4):531-8.
-
2012Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis., FEBS Lett 2012 Jun; 586(11): 1606-11.
-
2012Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template, J. Am. Chem. Soc. 2012 Apr;134(15):6732-40.
-
2011Structural and Functional Characterization of Anticoagulant, FXa-binding Viperidae Snake Venom Phospholipases A2, Acta Chim Slov 2011 Dec;58(4):671-7.
-
2011Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect, Hum. Mol. Genet. 2012 Feb;21(3):623-34.
-
2011Unravelling the conformational plasticity of the extracellular domain of a prokaryotic nAChR homologue in solution by NMR, Biochemistry 2011 Nov;50(45):9681-3.
-
2011Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses, J. Biol. Chem. 2011 Dec;286(49):42555-65.
-
2011Crystal structure of crotoxin reveals key residues involved in the stability and toxicity of this potent heterodimeric β-neurotoxin, J. Mol. Biol. 2011 Sep;412(2):176-91.
-
2011Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family, Proc. Natl. Acad. Sci. U.S.A. 2011 Jul;108(29):12143-8.
-
2011Structural basis for alcohol modulation of a pentameric ligand-gated ion channel, Proc. Natl. Acad. Sci. U.S.A. 2011 Jul;108(29):12149-54.
-
2011Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures, J. Mol. Graph. Model. 2011 Sep;30:100-9.
-
2011Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors, PLoS ONE 2011 Jan;6(1):e16519.
-
2011[The role of ectonucleotides metabolizing enzymes in purinergic signaling], Postepy Biochem. 2011;57(3):294-303.
-
2010Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis, J. Biol. Chem. 2010 Dec;285(53):41348-55.
-
20103D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels, Neuropharmacology 2011 Jan;60(1):116-25.
-
2010Rapid identification of multidrug-resistant tuberculosis isolates in treatment failure or relapse patients in Bangui, Central African Republic, Int. J. Tuberc. Lung Dis. 2010 Jun;14(6):782-5.
-
2010Functional and immunological characterization of the var2CSA-DBL5epsilon domain of a placental Plasmodium falciparum isolate, Mol. Biochem. Parasitol. 2010 Oct;173(2):115-22.
-
2010Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA, Proc. Natl. Acad. Sci. U.S.A. 2010 Mar;107(11):4884-9.
-
2010Biochemical and biophysical characterisation of DBL1alpha1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum, Mol. Biochem. Parasitol. 2010 Apr;170(2):84-92.
-
2009Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel, Anesth. Analg. 2010 Jan;110(1):59-63.
-
2009Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity, J. Struct. Biol. 2010 Mar;169(3):360-9.
-
2009Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells, PLoS ONE 2009 Oct;4(10):e7116.
-
2009Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system, Nat Rev Drug Discov 2009 Sep;8(9):733-50.
-
2009AftD, a novel essential arabinofuranosyltransferase from mycobacteria, Glycobiology 2009 Nov;19(11):1235-47.
-
2009Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy., J Am Chem Soc 2009 Feb; 131(5): 1736-44.
-
2008Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors, Neuroreport 2008 Oct;19(15):1545-50.
-
2008Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice, Mol. Microbiol. 2008 Nov;70(3):762-74.
-
2008Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics, Chemistry 2008;14(28):8521-9.
-
2007Deciphering the structural role of histidine 83 for heme binding in hemophore HasA., J Biol Chem 2008 Feb; 283(9): 5960-70.
-
2007A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra., J. Bacteriol. 2008 Feb; 190(4): 1329-34.
-
2007Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics, BMC Struct. Biol. 2007 Dec;7:82.
-
2007The first phospholipase inhibitor from the serum of Vipera ammodytes ammodytes, FEBS J. 2007 Dec;274(23):6055-64.
-
2007Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis, J. Biol. Chem. 2007 Sep;282(37):27270-6.
-
2006Cross-reactivity studies of an anti-Plasmodium vivax apical membrane antigen 1 monoclonal antibody: binding and structural characterisation, J. Mol. Biol. 2007 Mar;366(5):1523-37.
-
2006A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family, Nature 2007 Jan;445(7123):116-9.
-
2006Receptor-binding studies of the DBLgamma domain of Plasmodium falciparum erythrocyte membrane protein 1 from a placental isolate, Mol. Biochem. Parasitol. 2007 Jan;151(1):89-99.
-
2006Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors, Proc. Natl. Acad. Sci. U.S.A. 2006 Nov;103(45):16965-70.
-
2006The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth, J. Bacteriol. 2006 Nov;188(22):7778-84.
-
2006Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives, Microbes Infect. 2006 Jul;8(8):2245-53.
-
2006The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria., FEBS Lett 2006 May; 580(13): 3018-22.
-
2006Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity?, J. Physiol. Paris 2006 Mar-May;99(2-3):162-71.
-
2006Borrelia burgdorferi sensu stricto invasiveness is correlated with OspC-plasminogen affinity, Microbes Infect. 2006 Mar;8(3):645-52.
-
2006Direct-detected 13C NMR to investigate the iron(III) hemophore HasA., J Am Chem Soc 2006 Jan; 128(1): 150-8.
-
2005The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis, J. Biol. Chem. 2006 Jan;281(3):1313-6.
-
2005p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis, J. Biol. Chem. 2005 Dec;280(49):40699-706.
-
2005The C-terminal and beta-wing regions of ammodytoxin A, a neurotoxic phospholipase A2 from Vipera ammodytes ammodytes, are critical for binding to factor Xa and for anticoagulant effect, Biochimie 2006 Jan;88(1):69-76.
-
2005Nicotine upregulates its own receptors through enhanced intracellular maturation, Neuron 2005 May;46(4):595-607.
-
2004An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine, J. Biol. Chem. 2004 Apr;279(18):18767-75.
-
2004Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons, Eur. J. Neurosci. 2004 Feb;19(4):855-62.
-
2003Fcgamma receptor-like activity of hepatitis C virus core protein, J. Biol. Chem. 2004 Jan;279(4):2430-7.
-
2003An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors, EMBO J. 2003 May;22(9):1990-2003.
-
2003The neurotoxic phospholipase A2 associates, through a non-phosphorylated binding motif, with 14-3-3 protein gamma and epsilon isoforms, Biochem. Biophys. Res. Commun. 2003 Mar;302(4):691-6.
-
2003Crotoxin acceptor protein isolated from Torpedo electric organ: binding properties to crotoxin by surface plasmon resonance, Toxicon 2003 Mar;41(4):509-17.
-
2003Actin dynamics is controlled by a casein kinase II and phosphatase 2C interplay on Toxoplasma gondii Toxofilin, Mol. Biol. Cell 2003 May;14(5):1900-12.
-
2002The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences, J. Neurobiol. 2002 Dec;53(4):447-56.
-
2002Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints, FEBS Lett. 2002 Sep;528(1-3):251-6.
-
2002Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor, Proc. Natl. Acad. Sci. U.S.A. 2002 Mar;99(5):3216-21.
-
2002Inhibition of crotoxin phospholipase A(2) activity by manoalide associated with inactivation of crotoxin toxicity and dissociation of the heterodimeric neurotoxic complex, Biochem. Pharmacol. 2002 Feb;63(4):755-61.
-
2001A method for soluble overexpression of the alpha7 nicotinic acetylcholine receptor extracellular domain, Proc. Natl. Acad. Sci. U.S.A. 2001 Mar;98(6):3567-70.
-
2001Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit, Biochemistry 2001 Feb;40(7):2066-74.
-
2000Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor, J. Biol. Chem. 2000 Sep;275(38):29594-601.
-
2000Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy, Biochemistry 2000 Jun;39(23):6979-90.
-
2000Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors, Eur. J. Pharmacol. 2000 Mar;393(1-3):197-204.
-
2000Nicotinic receptors at the amino acid level, Annu. Rev. Pharmacol. Toxicol. 2000;40:431-58.
-
1999Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation, Biophys. J. 1999 May;76(5):2329-45.
-
1999Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor, Neuron 1999 Apr;22(4):831-43.
-
1998Brain nicotinic receptors: structure and regulation, role in learning and reinforcement, Brain Res. Brain Res. Rev. 1998 May;26(2-3):198-216.
-
1998Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors, J. Physiol. Paris 1998 Apr;92(2):107-11.
-
1998Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor, Mol. Pharmacol. 1998 Feb;53(2):283-94.
-
1998Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors, J. Neurosci. 1998 Jan;18(2):648-57.
-
1997Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants, Neuroreport 1997 Nov;8(16):3591-6.
-
1996Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor, EMBO J. 1996 Nov;15(21):5824-32.
-
1996Nicotinic receptors and brain plasticity, Cold Spring Harb. Symp. Quant. Biol. 1996;61:343-62.
-
1995Identification of a new component of the agonist binding site of the nicotinic alpha 7 homooligomeric receptor, J. Biol. Chem. 1995 May;270(20):11749-52.
-
1995CCKA, but not CCKB, agonists suppress the hyperlocomotion induced by endogenous enkephalins, protected from enzymatic degradation by systemic RB 101, Pharmacol. Biochem. Behav. 1995 Feb;50(2):133-9.
-
1993CCK-B agonist or antagonist activities of structurally hindered and peptidase-resistant Boc-CCK4 derivatives, J. Med. Chem. 1993 Jan;36(1):166-72.
-
1992[Study of induced effects by selective CCKB agonists cholecystokinin in the nociception and behavior in rodents], Therapie 1992 Nov;47(6):531-9.
-
1992[3H]pBC 264, a suitable probe for studying cholecystokinin-B receptors: binding characteristics in rodent brains and comparison with [3H]SNF 8702, Mol. Pharmacol. 1992 Jun;41(6):1089-95.
-
1989[3H]pBC 264, first highly potent and very selective radioligand for CCK-B receptors, Eur. J. Pharmacol. 1989 Sep;168(2):269-70.