• 2025
  Delphine Bonhomme, Hugo Vaysset, Eirene Marie Q. Ednacot, Vasco Rodrigues, Yazan Salloum, Jean Cury, Anny Wang, Axel Benchetrit, Pierre Affaticati, Veronica Hernandez Trejo, Paul Vittot, Charlie Bories, Alexis Cornec, Jean-Pierre Levraud, Pedro Hernández, Philippe Benaroch, Benjamin Morehouse, Aude Bernheim, Enzo Poirier, A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway, Science, 2025, 389 (6758), pp.eadr8536. ⟨10.1126/science.adr8536⟩.
• 2022
  Laghi V, Rezelj V, Boucontet L, Frétaud M, Da Costa B, Boudinot P, Salinas I, Lutfalla G, Vignuzzi M, Levraud JP, , Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder., Front Cell Infect Microbiol 2022 ; 12(): 790851.
• 2021
  Stressmann FA, Bernal-Bayard J, Perez-Pascual D, Audrain B, Rendueles O, Briolat V, Bruchmann S, Volant S, Ghozlane A, Häussler S, Duchaud E, Levraud JP, Ghigo JM, , Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection., ISME J 2021 Mar; 15(3): 702-719.
• 2020
  Colucci-Guyon E, Rifflet A, Saint-Auret S, da Costa A, Boucontet L, Laval T, Prehaud C, Blanchard N, Levraud JP, Boneca IG, Demangel C, Guenin-Macé L, , Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system., PLoS Negl Trop Dis 2020 Dec; 14(12): e0008878.
• 2019
  Maarifi G, Smith N, Maillet S, Moncorgé O, Chamontin C, Edouard J, Sohm F, Blanchet FP, Herbeuval JP, Lutfalla G, Levraud JP, Arhel NJ, Nisole S., TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells., Sci Adv. 2019 Nov 20;5(11):eaax3511.
• 2019
  Levraud JP, Jouneau L, Briolat V, Laghi V, Boudinot P, , IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity., J. Immunol. 2019 12; 203(12): 3361-3373.
• 2019
  Levraud JP, Herbomel P, Resident Macrophage Lookalikes of Unexpected Origin, Dev. Cell 2019 May;49(4):501-502.
• 2018
  Langevin C, Levraud JP, Boudinot P, Fish antiviral tripartite motif (TRIM) proteins, Fish Shellfish Immunol. 2019 Mar;86:724-733.
• 2018
  Hernández PP, Strzelecka PM, Athanasiadis EI, Hall D, Robalo AF, Collins CM, Boudinot P, Levraud JP, Cvejic A, Single-cell transcriptional analysis reveals ILC-like cells in zebrafish, Sci Immunol 2018 Nov;3(29).
• 2018
  Phan QT, Sipka T, Gonzalez C, Levraud JP, Lutfalla G, Nguyen-Chi M, Neutrophils use superoxide to control bacterial infection at a distance, PLoS Pathog. 2018 Jul;14(7):e1007157.
• 2018
  Boucontet L, Passoni G, Thiry V, Maggi L, Herbomel P, Levraud JP, Colucci-Guyon E, A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death, Front Immunol 2018;9:1084.
• 2017
  Mounce BC, Cesaro T, Vlajnić L, Vidiņa A, Vallet T, Weger-Lucarelli J, Passoni G, Stapleford KA, Levraud JP, Vignuzzi M, Chikungunya Virus Overcomes Polyamine Depletion by Mutation of nsP1 and the Opal Stop Codon To Confer Enhanced Replication and Fitness, J. Virol. 2017 08;91(15).
• 2017
  Aguado LC, Schmid S, May J, Sabin LR, Panis M, Blanco-Melo D, Shim JV, Sachs D, Cherry S, Simon AE, Levraud JP, tenOever BR, RNase III nucleases from diverse kingdoms serve as antiviral effectors, Nature 2017 07;547(7661):114-117.
• 2017
  Passoni G, Langevin C, Palha N, Mounce BC, Briolat V, Affaticati P, De Job E, Joly JS, Vignuzzi M, Saleh MC, Herbomel P, Boudinot P, Levraud JP, , Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes., Dis Model Mech 2017 Jul; 10(7): 847-857.
• 2017
  Langevin C, Aleksejeva E, Houel A, Briolat V, Torhy C, Lunazzi A, Levraud JP, Boudinot P, , FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection., Front Immunol 2017 ; 8(): 617.
• 2017
  Rességuier J, Delaune E, Coolen AL, Levraud JP, Boudinot P, Le Guellec D, Verrier B, Specific and Efficient Uptake of Surfactant-Free Poly(Lactic Acid) Nanovaccine Vehicles by Mucosal Dendritic Cells in Adult Zebrafish after Bath Immersion, Front Immunol 2017;8:190.
• 2016
  Boudinot P, Langevin C, Secombes CJ, Levraud JP, The Peculiar Characteristics of Fish Type I Interferons, Viruses 2016 11;8(11).
• 2016
  Mounce BC, Poirier EZ, Passoni G, Simon-Loriere E, Cesaro T, Prot M, Stapleford KA, Moratorio G, Sakuntabhai A, Levraud JP, Vignuzzi M, , Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses., Cell Host Microbe 2016 Aug; 20(2): 167-77.
• 2015
  Aleksejeva E, Houel A, Briolat V, Levraud JP, Langevin C, Boudinot P, Zebrafish Plzf transcription factors enhance early type I IFN response induced by two non-enveloped RNA viruses, Dev. Comp. Immunol. 2016 Apr;57:48-56.
• 2015
  Nguyen Chi M, Laplace-Builhe B, Travnickova J, Luz-Crawford P, Tejedor G, Phan QT, Duroux-Richard I, Levraud JP, Kissa K, Lutfalla G, Jorgensen C, Djouad F, Identification of polarized macrophage subsets in zebrafish, Elife 2015 Jul;4.
• 2015
  Kasher PR, Jenkinson EM, Briolat V, Gent D, Morrissey C, Zeef LA, Rice GI, Levraud JP, Crow YJ, , Characterization of samhd1 morphant zebrafish recapitulates features of the human type I interferonopathy Aicardi-Goutières syndrome., J. Immunol. 2015 Mar; 194(6): 2819-25.
• 2014
  Nguyen-Chi M, Phan QT, Gonzalez C, Dubremetz JF, Levraud JP, Lutfalla G, Transient infection of the zebrafish notochord with E. coli induces chronic inflammation, Dis Model Mech 2014 Jul;7(7):871-82.
• 2014
  Levraud JP, Palha N, Langevin C, Boudinot P, Through the looking glass: witnessing host-virus interplay in zebrafish, Trends Microbiol. 2014 Sep;22(9):490-7.
• 2014
  Siupka P, Hamming OJ, Frétaud M, Luftalla G, Levraud JP, Hartmann R, The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22, Genes Immun. 2014 Jul-Aug;15(5):293-302.
• 2014
  Briolat V, Jouneau L, Carvalho R, Palha N, Langevin C, Herbomel P, Schwartz O, Spaink HP, Levraud JP, Boudinot P, , Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes., J. Immunol. 2014 May; 192(9): 4328-41.
• 2013
  Langevin C, Aleksejeva E, Passoni G, Palha N, Levraud JP, Boudinot P, The antiviral innate immune response in fish: evolution and conservation of the IFN system, J. Mol. Biol. 2013 Dec;425(24):4904-20.
• 2013
  Mostowy S, Boucontet L, Mazon Moya MJ, Sirianni A, Boudinot P, Hollinshead M, Cossart P, Herbomel P, Levraud JP, Colucci-Guyon E, The zebrafish as a new model for the in vivo study of Shigella flexneri interaction with phagocytes and bacterial autophagy, PLoS Pathog. 2013;9(9):e1003588.
• 2013
  Palha N, Guivel-Benhassine F, Briolat V, Lutfalla G, Sourisseau M, Ellett F, Wang CH, Lieschke GJ, Herbomel P, Schwartz O, Levraud JP, , Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish., PLoS Pathog. 2013 ; 9(9): e1003619.
• 2013
  Langevin C, van der Aa LM, Houel A, Torhy C, Briolat V, Lunazzi A, Harmache A, Bremont M, Levraud JP, Boudinot P, Zebrafish ISG15 exerts a strong antiviral activity against RNA and DNA viruses and regulates the interferon response, J. Virol. 2013 Sep;87(18):10025-36.
• 2012
  Rendueles O, Ferrières L, Frétaud M, Bégaud E, Herbomel P, Levraud JP, Ghigo JM, A new zebrafish model of oro-intestinal pathogen colonization reveals a key role for adhesion in protection by probiotic bacteria, PLoS Pathog. 2012;8(7):e1002815.
• 2012
  van der Aa LM, Chadzinska M, Derks W, Scheer M, Levraud JP, Boudinot P, Lidy Verburg-van Kemenade BM, Diversification of IFNγ-inducible CXCb chemokines in cyprinid fish, Dev. Comp. Immunol. 2012 Oct;38(2):243-53.
• 2011
  Boudinot P, van der Aa LM, Jouneau L, Du Pasquier L, Pontarotti P, Briolat V, Benmansour A, Levraud JP, Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish, PLoS ONE 2011;6(7):e22022.
• 2011
  Hamming OJ, Lutfalla G, Levraud JP, Hartmann R, Crystal structure of Zebrafish interferons I and II reveals conservation of type I interferon structure in vertebrates, J. Virol. 2011 Aug;85(16):8181-7.
• 2011
  Ludwig M, Palha N, Torhy C, Briolat V, Colucci-Guyon E, Brémont M, Herbomel P, Boudinot P, Levraud JP, , Whole-body analysis of a viral infection: vascular endothelium is a primary target of infectious hematopoietic necrosis virus in zebrafish larvae., PLoS Pathog. 2011 Feb; 7(2): e1001269.
• 2010
  Aggad D, Stein C, Sieger D, Mazel M, Boudinot P, Herbomel P, Levraud JP, Lutfalla G, Leptin M, In vivo analysis of Ifn-γ1 and Ifn-γ2 signaling in zebrafish, J. Immunol. 2010 Dec;185(11):6774-82.
• 2009
  Levraud JP, Disson O, Kissa K, Bonne I, Cossart P, Herbomel P, Lecuit M, , Real-time observation of listeria monocytogenes-phagocyte interactions in living zebrafish larvae., Infect Immun 2009 Sep; 77(9): 3651-60.
• 2009
  Aggad D, Mazel M, Boudinot P, Mogensen KE, Hamming OJ, Hartmann R, Kotenko S, Herbomel P, Lutfalla G, Levraud JP, The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains, J. Immunol. 2009 Sep;183(6):3924-31.
• 2009
  Levraud JP, Boudinot P, [The immune system of teleost fish], Med Sci (Paris) 2009 Apr;25(4):405-11.
• 2009
  van der Aa LM, Levraud JP, Yahmi M, Lauret E, Briolat V, Herbomel P, Benmansour A, Boudinot P, A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish, BMC Biol. 2009;7:7.
• 2008
  Levraud JP, Colucci-Guyon E, Redd MJ, Lutfalla G, Herbomel P, In vivo analysis of zebrafish innate immunity, Methods Mol. Biol. 2008;415:337-63.
• 2007
  Lam D, Levraud JP, Luciani MF, Golstein P, Autophagic or necrotic cell death in the absence of caspase and bcl-2 family members, Biochem. Biophys. Res. Commun. 2007 Nov;363(3):536-41.
• 2007
  Levraud JP, Boudinot P, Colin I, Benmansour A, Peyrieras N, Herbomel P, Lutfalla G, Identification of the zebrafish IFN receptor: implications for the origin of the vertebrate IFN system, J. Immunol. 2007 Apr;178(7):4385-94.
• 2005
  Herbomel P, Levraud JP, Imaging early macrophage differentiation, migration, and behaviors in live zebrafish embryos, Methods Mol. Med. 2005;105:199-214.
• 2003
  Roisin-Bouffay C, Luciani MF, Klein G, Levraud JP, Adam M, Golstein P, Developmental cell death in dictyostelium does not require paracaspase, J. Biol. Chem. 2004 Mar;279(12):11489-94.
• 2003
  Golstein P, Aubry L, Levraud JP, Cell-death alternative model organisms: why and which?, Nat. Rev. Mol. Cell Biol. 2003 Oct;4(10):798-807.
• 2003
  Levraud JP, Adam M, Luciani MF, de Chastellier C, Blanton RL, Golstein P, Dictyostelium cell death: early emergence and demise of highly polarized paddle cells, J. Cell Biol. 2003 Mar;160(7):1105-14.
• 2001
  Levraud JP, Adam M, Cornillon S, Golstein P, Methods to study cell death in Dictyostelium discoideum, Methods Cell Biol. 2001;66:469-97.
• 2000
  Haymann JP, Levraud JP, Bouet S, Kappes V, Hagège J, Nguyen G, Xu Y, Rondeau E, Sraer JD, Characterization and localization of the neonatal Fc receptor in adult human kidney, J. Am. Soc. Nephrol. 2000 Apr;11(4):632-9.
• 1999
  Gerber DJ, Azuara V, Levraud JP, Huang SY, Lembezat MP, Pereira P, IL-4-producing gamma delta T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen, J. Immunol. 1999 Sep;163(6):3076-82.
• 1999
  Bellio M, Liveira AC, Mermelstein CS, Capella MA, Viola JP, Levraud JP, Dosreis GA, Previato JO, Mendonça-Previato L, Costimulatory action of glycoinositolphospholipids from Trypanosoma cruzi: increased interleukin 2 secretion and induction of nuclear translocation of the nuclear factor of activated T cells 1, FASEB J. 1999 Sep;13(12):1627-36.
• 1999
  Bousso P, Levraud JP, Kourilsky P, Abastado JP, The composition of a primary T cell response is largely determined by the timing of recruitment of individual T cell clones, J. Exp. Med. 1999 May;189(10):1591-600.
• 1999
  Weil R, Levraud JP, Dodon MD, Bessia C, Hazan U, Kourilsky P, Israël A, Altered expression of tyrosine kinases of the Src and Syk families in human T-cell leukemia virus type 1-infected T-cell lines, J. Virol. 1999 May;73(5):3709-17.
• 1999
  Fernandez NC, Levraud JP, Haddada H, Perricaudet M, Kourilsky P, High frequency of specific CD8+ T cells in the tumor and blood is associated with efficient local IL-12 gene therapy of cancer, J. Immunol. 1999 Jan;162(1):609-17.
• 1998
  Lone YC, Motta I, Mottez E, Guilloux Y, Lim A, Demay F, Levraud JP, Kourilsky P, Abastado JP, In vitro induction of specific cytotoxic T lymphocytes using recombinant single-chain MHC class I/peptide complexes, J. Immunother. 1998 Jul;21(4):283-94.
• 1997
  Levraud JP, Duffour MT, Cordier L, Perricaudet M, Haddada H, Kourilsky P, IL-2 gene delivery within an established murine tumor causes its regression without proliferation of preexisting antitumor-specific CTL, J. Immunol. 1997 Apr;158(7):3335-43.
• 1997
  Azuara V, Levraud JP, Lembezat MP, Pereira P, A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire, Eur. J. Immunol. 1997 Feb;27(2):544-53.
• 1996
  Regnault A, Levraud JP, Lim A, Six A, Moreau C, Cumano A, Kourilsky P, The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones, Eur. J. Immunol. 1996 Apr;26(4):914-21.
• 1996
  Levraud JP, Pannetier C, Langlade-Demoyen P, Brichard V, Kourilsky P, Recurrent T cell receptor rearrangements in the cytotoxic T lymphocyte response in vivo against the p815 murine tumor, J. Exp. Med. 1996 Feb;183(2):439-49.