• 2024
  Valentin Bonnet, Erik Maikranz, Marianne Madec, Nadia Vertti-Quintero, Céline Cuche, Marta Mastrogiovanni, Andrés Alcover, Vincenzo Di Bartolo, Charles N Baroud, Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids, Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (11), pp.e2316500121. ⟨10.1073/pnas.2316500121⟩.
• 2023
  Céline Cuche, Marta Mastrogiovanni, Marie Juzans, Hélène Laude, Marie-Noëlle Ungeheuer, Daniel Krentzel, Maria Isabella Gariboldi, Daniel Scott-Algara, Marianne Madec, Sophie Goyard, Camille Floch, Gaëlle Chauveau-Le Friec, Pierre Lafaye, Charlotte Renaudat, Muriel Le Bidan, Christine Micallef, Sandrine Schmutz, Sébastien Mella, Sophie Novault, Milena Hasan, Darragh Duffy, Vincenzo Di Bartolo, Andrés Alcover, T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations, Frontiers in Immunology, 2023, 14, pp.1163466. ⟨10.3389/fimmu.2023.1163466⟩.
• 2022
  Mastrogiovanni M, Vargas P, Rose T, Cuche C, Esposito E, Juzans M, Laude H, Schneider A, Bernard M, Goyard S, Renaudat C, Ungeheuer MN, Delon J, Alcover A, Di Bartolo V, , The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration., Sci Adv 2022 Apr; 8(15): eabl5942.
• 2021
  Mastrogiovanni M, Di Bartolo V, Alcover A, Cell Polarity Regulators, Multifunctional Organizers of Lymphocyte Activation and Function., Biomed J 2021 Oct; (): .
• 2020
  Mastrogiovanni M, Juzans M, Alcover A, Di Bartolo V, , Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions., Front Cell Dev Biol 2020 ; 8(): 591348.
• 2020
  Juzans M, Cuche C, Rose T, Mastrogiovanni M, Bochet P, Di Bartolo V, Alcover A, , Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions., Immunohorizons 2020 06; 4(6): 363-381.
• 2020
  Ghosh S, Di Bartolo V, Tubul L, Shimoni E, Kartvelishvily E, Dadosh T, Feigelson SW, Alon R, Alcover A, Haran G, , ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation., Cell Rep 2020 Mar; 30(10): 3434-3447.e6.
• 2018
  Del Río-Iñiguez I, Vázquez-Chávez E, Cuche C, Di Bartolo V, Bouchet J, Alcover A, , HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton-Mediated T Cell Functions., J. Immunol. 2018 11; 201(9): 2624-2640.
• 2018
  Alcover A, Alarcón B, Di Bartolo V, , Cell Biology of T Cell Receptor Expression and Regulation., Annu. Rev. Immunol. 2018 04; 36(): 103-125.
• 2017
  Agüera-González S, Burton OT, Vázquez-Chávez E, Cuche C, Herit F, Bouchet J, Lasserre R, Del Río-Iñiguez I, Di Bartolo V, Alcover A, , Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization., Cell Rep 2017 Oct; 21(1): 181-194.
• 2017
  Del Río-Iñiguez I, Bouchet J, Alcover A, Studying the Immune Synapse in HIV-1 Infection, Methods Mol. Biol. 2017;1584:545-557.
• 2017
  Bouchet J, Del Río-Iñiguez I, Alcover A, Imaging Vesicular Traffic at the Immune Synapse, Methods Mol. Biol. 2017;1584:129-142.
• 2016
  Bouchet J, McCaffrey MW, Graziani A, Alcover A, The functional interplay of Rab11, FIP3 and Rho proteins on the endosomal recycling pathway controls cell shape and symmetry, Small GTPases 2016 Aug;:1-6.
• 2015
  Sonia Agüera-Gonzalez, Jérôme Bouchet, Andrés Alcover, Immunological Synapse, eLS John Wiley & Sons, Ltd: Chichester DOI: 10.1002/9780470015902.a0004027.pub2.
• 2015
  Bordería AV, Isakov O, Moratorio G, Henningsson R, Agüera-González S, Organtini L, Gnädig NF, Blanc H, Alcover A, Hafenstein S, Fontes M, Shomron N, Vignuzzi M, Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype, PLoS Pathog. 2015 May;11(5):e1004838.
• 2014
  Bouchet J, Alcover A, [Immunological synapse is a dynamic signaling platform for T cell activation], Med Sci (Paris) 2014 Jun-Jul;30(6-7):665-70.
• 2013
  Soares H, Lasserre R, Alcover A, Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses, Immunol. Rev. 2013 Nov;256(1):118-32.
• 2013
  Soares H, Henriques R, Sachse M, Ventimiglia L, Alonso MA, Zimmer C, Thoulouze MI, Alcover A, Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse, J. Exp. Med. 2013 Oct;210(11):2415-33.
• 2012
  Lasserre R, Alcover A, Microtubule dynamics and signal transduction at the immunological synapse: new partners and new connections, EMBO J. 2012 Nov;31(21):4100-2.
• 2011
  Lasserre R, Cuche C, Blecher-Gonen R, Libman E, Biquand E, Danckaert A, Yablonski D, Alcover A, Di Bartolo V, , Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation., J. Cell Biol. 2011 Nov; 195(5): 839-53.
• 2011
  Thoulouze MI, Alcover A, Can viruses form biofilms?, Trends Microbiol. 2011 Jun;19(6):257-62.
• 2010
  Lasserre R, Alcover A, Cytoskeletal cross-talk in the control of T cell antigen receptor signaling, FEBS Lett. 2010 Dec;584(24):4845-50.
• 2010
  Alcover A, Thoulouze MI, Vesicle traffic to the immunological synapse: a multifunctional process targeted by lymphotropic viruses, Curr. Top. Microbiol. Immunol. 2010;340:191-207.
• 2009
  Pais-Correia AM, Sachse M, Guadagnini S, Robbiati V, Lasserre R, Gessain A, Gout O, Alcover A, Thoulouze MI, Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses, Nat. Med. 2010 Jan;16(1):83-9.
• 2007
  Fackler OT, Alcover A, Schwartz O, Modulation of the immunological synapse: a key to HIV-1 pathogenesis?, Nat Rev Immunol. 2007 Apr;7(4):310-7.
• 2006
  Thoulouze MI, Sol-Foulon N, Blanchet F, Dautry-Varsat A, Schwartz O, Alcover A, Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse, Immunity 2006 May;24(5):547-61.
• 2006
  Charrin S, Alcover A, Role of ERM (ezrin-radixin-moesin) proteins in T lymphocyte polarization, immune synapse formation and in T cell receptor-mediated signaling, Front. Biosci. 2006;11:1987-97.
• 2005
  Balañá ME, Niedergang F, Subtil A, Alcover A, Chavrier P, Dautry-Varsat A, ARF6 GTPase controls bacterial invasion by actin remodelling, J. Cell. Sci. 2005 May;118(Pt 10):2201-10.
• 2004
  Coumailleau F, Das V, Alcover A, Raposo G, Vandormael-Pournin S, Le Bras S, Baldacci P, Dautry-Varsat A, Babinet C, Cohen-Tannoudji M, Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment, Mol. Biol. Cell 2004 Oct;15(10):4444-56.
• 2004
  Das V, Nal B, Dujeancourt A, Thoulouze MI, Galli T, Roux P, Dautry-Varsat A, Alcover A, Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes, Immunity 2004 May;20(5):577-88.
• 2003
  Mascarell L, Auger R, Alcover A, Ojcius DM, Jungas T, Cadet-Daniel V, Kanellopoulos JM, Truffa-Bachi P, Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin A in activated T cells, J. Biol. Chem. 2004 Mar;279(11):10556-63.
• 2003
  Ragimbeau J, Dondi E, Alcover A, Eid P, Uzé G, Pellegrini S, The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression, EMBO J. 2003 Feb;22(3):537-47.
• 2003
  Roumier A, Niedergang F, Alcover A, T-lymphocyte activation induced by staphylococcal enterotoxin superantigens. Analysis of protein tyrosine phosphorylation, Methods Mol. Biol. 2003;214:127-35.
• 2003
  Weil R, Schwamborn K, Alcover A, Bessia C, Di Bartolo V, Israël A, Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor, Immunity 2003 Jan;18(1):13-26.
• 2002
  Das V, Nal B, Roumier A, Meas-Yedid V, Zimmer C, Olivo-Marin JC, Roux P, Ferrier P, Dautry-Varsat A, Alcover A, Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T-cell activation, Immunol. Rev. 2002 Nov;189:123-35.
• 2002
  Groysman M, Hornstein I, Alcover A, Katzav S, Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways, J. Biol. Chem. 2002 Dec;277(51):50121-30.
• 2002
  Payelle-Brogard B, Magnac C, Alcover A, Roux P, Dighiero G, Defective assembly of the B-cell receptor chains accounts for its low expression in B-chronic lymphocytic leukaemia, Br. J. Haematol. 2002 Sep;118(4):976-85.
• 2002
  Montoya MC, Sancho D, Bonello G, Collette Y, Langlet C, He HT, Aparicio P, Alcover A, Olive D, Sánchez-Madrid F, Role of ICAM-3 in the initial interaction of T lymphocytes and APCs, Nat. Immunol. 2002 Feb;3(2):159-68.
• 2000
  Borroto A, Gil D, Delgado P, Vicente-Manzanares M, Alcover A, Sánchez-Madrid F, Alarcón B, Rho regulates T cell receptor ITAM-induced lymphocyte spreading in an integrin-independent manner, Eur. J. Immunol. 2000 Dec;30(12):3403-10.
• 2000
  Michel F, Mangino G, Attal-Bonnefoy G, Tuosto L, Alcover A, Roumier A, Olive D, Acuto O, , CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation., J Immunol 2000 Oct; 165(7): 3820-9.
• 2000
  Rubin B, Llobera R, Gouaillard C, Alcover A, Arnaud J, Dissection of the role of CD3gamma chains in profound but reversible T-cell receptor down-regulation, Scand. J. Immunol. 2000 Aug;52(2):173-83.
• 2000
  Niedergang F, Alcover A, Knight CG, Farndale RW, Barnes MJ, Francischetti IM, Bon C, Leduc M, Convulxin binding to platelet receptor GPVI: competition with collagen related peptides, Biochem. Biophys. Res. Commun. 2000 Jun;273(1):246-50.
• 2000
  San José E, Borroto A, Niedergang F, Alcover A, Alarcón B, Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism, Immunity 2000 Feb;12(2):161-70.
• 2000
  Alcover A, Alarcón B, Internalization and intracellular fate of TCR-CD3 complexes, Crit. Rev. Immunol. 2000;20(4):325-46.
• 1999
  Borroto A, Lama J, Niedergang F, Dautry-Varsat A, Alarcón B, Alcover A, The CD3 epsilon subunit of the TCR contains endocytosis signals, J. Immunol. 1999 Jul;163(1):25-31.
• 1998
  Niedergang F, Dautry-Varsat A, Alcover A, Cooperative activation of TCRs by enterotoxin superantigens, J. Immunol. 1998 Dec;161(11):6054-8.
• 1997
  Niedergang F, Dautry-Varsat A, Alcover A, Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors, J. Immunol. 1997 Aug;159(4):1703-10.
• 1997
  Niedergang F, San José E, Rubin B, Alarcón B, Dautry-Varsat A, Alcover A, Differential cytosolic tail dependence and intracellular fate of T-cell receptors internalized upon activation with superantigen or phorbol ester, Res. Immunol. 1997 May;148(4):231-45.
• 1996
  Duplay P, Alcover A, Fargeas C, Sékaly RP, Branton PE, An activated epidermal growth factor receptor/Lck chimera restores early T cell receptor-mediated calcium response in a CD45-deficient T cell line, J. Biol. Chem. 1996 Jul;271(30):17896-902.
• 1996
  Prieur E, Betbeder D, Niedergang F, Major M, Alcover A, Davignon JL, Davrinche C, Combination of human cytomegalovirus recombinant immediate-early protein (IE1) with 80 nm cationic biovectors: protection from proteolysis and potentiation of presentation to CD4+ T-cell clones in vitro, Vaccine 1996 Apr;14(6):511-20.
• 1995
  Niedergang F, Hémar A, Hewitt CR, Owen MJ, Dautry-Varsat A, Alcover A, The Staphylococcus aureus enterotoxin B superantigen induces specific T cell receptor down-regulation by increasing its internalization, J. Biol. Chem. 1995 May;270(21):12839-45.
• 1994
  Lafont V, Dornand J, d'Angeac AD, Monier S, Alcover A, Favero J, Jacalin, a lectin that inhibits in vitro HIV-1 infection, induces intracellular calcium increase via CD4 in cells lacking the CD3/TcR complex, J. Leukoc. Biol. 1994 Oct;56(4):521-4.
• 1993
  Boursier JP, Alcover A, Herve F, Laisney I, Acuto O, Evidence for an extended structure of the T-cell co-receptor CD8 alpha as deduced from the hydrodynamic properties of soluble forms of the extracellular region, J. Biol. Chem. 1993 Jan;268(3):2013-20.
• 1993
  Alcover A, Hervé F, Boursier JP, Spagnoli G, Olive D, Mariuzza RA, Acuto O, A soluble form of the human CD8 alpha chain expressed in the baculovirus system: biochemical characterization and binding to MHC class I, Mol. Immunol. 1993 Jan;30(1):55-67.
• 1992
  Danielian S, Alcover A, Polissard L, Stefanescu M, Acuto O, Fischer S, Fagard R, Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck, Eur. J. Immunol. 1992 Nov;22(11):2915-21.
• 1992
  Alcover A, Juillard V, Acuto O, Engagement of major histocompatibility complex class I and class II molecules up-regulates intercellular adhesion of human B cells via a CD11/CD18-independent mechanism, Eur. J. Immunol. 1992 Feb;22(2):405-12.
• 1991
  Danielian S, Fagard R, Alcover A, Acuto O, Fischer S, The tyrosine kinase activity of p56lck is increased in human T cells activated via CD2, Eur. J. Immunol. 1991 Aug;21(8):1967-70.
• 1990
  Moingeon P, Jin YJ, Stebbins CC, Lopez PA, Alcover A, Reinherz EL, Characterization of functional GTP binding proteins in Jurkat T cell mutants lacking either CD3-Ti or CD2 surface receptors, Cell. Immunol. 1990 Jul;128(2):578-88.
• 1990
  Alcover A, Mariuzza RA, Ermonval M, Acuto O, Lysine 271 in the transmembrane domain of the T-cell antigen receptor beta chain is necessary for its assembly with the CD3 complex but not for alpha/beta dimerization, J. Biol. Chem. 1990 Mar;265(7):4131-5.
• 1989
  Danielian S, Fagard R, Alcover A, Acuto O, Fischer S, The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2, Eur. J. Immunol. 1989 Dec;19(12):2183-9.
• 1989
  Moingeon P, Chang HC, Sayre PH, Clayton LK, Alcover A, Gardner P, Reinherz EL, The structural biology of CD2, Immunol. Rev. 1989 Oct;111:111-44.
• 1989
  Testi R, Alcover A, Spagnoli G, Reinherz EL, Acuto O, CD3Ti+ human thymocyte-derived clones displaying a differential response to activation via CD3Ti and CD2, Cell. Immunol. 1989 Sep;122(2):350-64.
• 1989
  Gardner P, Alcover A, Kuno M, Moingeon P, Weyand CM, Goronzy J, Reinherz EL, Triggering of T-lymphocytes via either T3-Ti or T11 surface structures opens a voltage-insensitive plasma membrane calcium-permeable channel: requirement for interleukin-2 gene function, J. Biol. Chem. 1989 Jan;264(2):1068-76.
• 1988
  Moingeon P, Alcover A, Clayton LK, Chang HC, Transy C, Reinherz EL, Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants, J. Exp. Med. 1988 Dec;168(6):2077-90.
• 1988
  Alcover A, Alberini C, Acuto O, Clayton LK, Transy C, Spagnoli GC, Moingeon P, Lopez P, Reinherz EL, Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes, EMBO J. 1988 Jul;7(7):1973-7.
• 1988
  Alcover A, Chang HC, Sayre PH, Hussey RE, Reinherz EL, The T 11 (CD 2) cDNA encodes a transmembrane protein which expresses T 11(1), T 11(2) and T 11(3) epitopes but which does not independently mediate calcium influx: analysis by gene transfer in a baculovirus system, Eur. J. Immunol. 1988 Mar;18(3):363-7.
• 1987
  Pecht I, Corcia A, Liuzzi MP, Alcover A, Reinherz EL, Ion channels activated by specific Ti or T3 antibodies in plasma membranes of human T cells, EMBO J. 1987 Jul;6(7):1935-9.
• 1987
  Alcover A, Ramarli D, Richardson NE, Chang HC, Reinherz EL, Functional and molecular aspects of human T lymphocyte activation via T3-Ti and T11 pathways, Immunol. Rev. 1987 Feb;95:5-36.
• 1986
  Alcover A, Weiss MJ, Daley JF, Reinherz EL, The T11 glycoprotein is functionally linked to a calcium channel in precursor and mature T-lineage cells, Proc. Natl. Acad. Sci. U.S.A. 1986 Apr;83(8):2614-8.
• 1985
  Alcover A, Hernández C, Avila J, Human vimentin autoantibodies preferentially interact with a peptide of 30kD mol. wt, located close to the amino-terminal of the molecule, Clin. Exp. Immunol. 1985 Jul;61(1):24-30.
• 1985
  Alcover A, Ramirez-Lafita F, Hernandez C, Nieto A, Avila J, Antibodies to vimentin intermediate filaments in sera from patients with SLE and RA: quantitation by solid phase radioimmunoassay, J. Rheumatol. 1985 Apr;12(2):233-6.
• 1984
  Alcover A, Molano J, Renart J, Gil-Aguado A, Nieto A, Avila J, Antibodies to vimentin intermediate filaments in sera from patients with systemic lupus erythematosus, Arthritis Rheum. 1984 Aug;27(8):922-8.
• 1982
  Alcover A, Izquierdo M, Stollar D, Kitagawa Y, Miranda M, Alonso C, In situ immunofluorescent visualization of chromosomal transcripts in polytene chromosomes, Chromosoma 1982;87(3):263-77.
• 1981
  Alcover A, Izquierdo M, Stolar D, Miranda M, Alonso C, Analytical studies of chromosomal transcription detected by an endogenous hybridization technique (EHT) using autoradiography and indirect immunofluorescence in Drosophila hydei, Acta Embryol Morphol Exp 1981 Dec;2(2):131-40.