• 2024
  Vemparala B, Madelain V, Passaes C, Millet A, Avettand-Fenoel V, Djidjou-Demasse R, Dereuddre-Bosquet N, Le Grand R, Rouzioux C, Vaslin B, Sáez-Cirión A, Guedj J, Dixit NM, Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection: Learning in vivo dynamics using ex vivo data., PLoS Comput Biol 2024 Sep; 20(9): e1012434.
• 2024
  Sáez-Cirión A, Mamez AC, Avettand-Fenoel V, Nabergoj M, Passaes C, Thoueille P, Decosterd L, Hentzien M, Perdomo-Celis F, Salgado M, Nijhuis M, Melard A, Gardiennet E, Lorin V, Monceaux V, Chapel A, Gourves M, Lechartier M, Mouquet H, Wensing A, Picado JM, Yerly S, Rougemont M, Calmy A, Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells., Nat Med 2024 Sep; (): .
• 2024
  Strongin Z, Raymond Marchand L, Deleage C, Pampena MB, Cardenas MA, Beusch CM, Hoang TN, Urban EA, Gourves M, Nguyen K, Tharp GK, Lapp S, Rahmberg AR, Harper J, Del Rio Estrada PM, Gonzalez-Navarro M, Torres-Ruiz F, Luna-Villalobos YA, Avila-Rios S, Reyes-Teran G, Sekaly R, Silvestri G, Kulpa DA, Saez-Cirion A, Brenchley JM, Bosinger SE, Gordon DE, Betts MR, Kissick HT, Paiardini M, Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence., Nat Immunol 2024 Jun; (): .
• 2024
  De La Torre Tarazona E, Passaes C, Moreno S, Sáez-Cirión A, Alcamí J, High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells., Sci Rep 2024 Jun; 14(1): 13980.
• 2024
  Salgado M, Gálvez C, Nijhuis M, Kwon M, Cardozo-Ojeda EF, Badiola J, Gorman MJ, Huyveneers LEP, Urrea V, Bandera A, Jensen BO, Vandekerckhove L, Jurado M, Raj K, Schulze Zur Wiesch J, Bailén R, Eberhard JM, Nabergoj M, Hütter G, Saldaña-Moreno R, Oldford S, Barrett L, Ramirez MLM, Garba S, Gupta RK, Revollo B, Ferra-Coll C, Kuball J, Alter G, Sáez-Cirión A, Diez-Martin JL, Duke ER, Schiffer JT, Wensing A, Martinez-Picado J, Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study., Lancet HIV 2024 Jun; 11(6): e389-e405.
• 2024
  Cabral-Piccin MP, Briceño O, Papagno L, Liouville B, White E, Perdomo-Celis F, Autaa G, Volant S, Llewellyn-Lacey S, Fromentin R, Chomont N, Price DA, Sáez-Cirión A, Lambotte O, Katlama C, Appay V, CD8 + T-cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy., AIDS 2024 Feb; 38(2): 161-166.
• 2024
  Passaes C, Desjardins D, Chapel A, Monceaux V, Lemaitre J, Mélard A, Perdomo-Celis F, Planchais C, Gourvès M, Dimant N, David A, Dereuddre-Bosquet N, Barrail-Tran A, Gouget H, Guillaume C, Relouzat F, Lambotte O, Guedj J, Müller-Trutwin M, Mouquet H, Rouzioux C, Avettand-Fenoël V, Le Grand R, Sáez-Cirión A, Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8+ T-cells., Nat Commun 2024 Jan; 15(1): 178.
• 2023
  Flescq C, Gachon A, Saez Cirion A, [A shot of synTac to activate CD8+ T cells cytotoxic specific response against HIV]., Med Sci (Paris) 2023 Oct; 39(10): 783-786.
• 2023
  Molinos-Albert LM, Baquero E, Bouvin-Pley M, Lorin V, Charre C, Planchais C, Dimitrov JD, Monceaux V, Vos M, , Hocqueloux L, Berger JL, Seaman MS, Braibant M, Avettand-Fenoël V, Sáez-Cirión A, Mouquet H, Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller., Cell Host Microbe 2023 Jul; (): .
• 2023
  Cabral-Piccin MP, Papagno L, Lahaye X, Perdomo-Celis F, Volant S, White E, Monceaux V, Llewellyn-Lacey S, Fromentin R, Price DA, Chomont N, Manel N, Saez-Cirion A, Appay V, Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection., EBioMedicine 2023 Apr; 91(): 104557.
• 2023
  Jensen BO, Knops E, Cords L, Lübke N, Salgado M, Busman-Sahay K, Estes JD, Huyveneers LEP, Perdomo-Celis F, Wittner M, Gálvez C, Mummert C, Passaes C, Eberhard JM, Münk C, Hauber I, Hauber J, Heger E, De Clercq J, Vandekerckhove L, Bergmann S, Dunay GA, Klein F, Häussinger D, Fischer JC, Nachtkamp K, Timm J, Kaiser R, Harrer T, Luedde T, Nijhuis M, Sáez-Cirión A, Schulze Zur Wiesch J, Wensing AMJ, Martinez-Picado J, Kobbe G, , In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation., Nat Med 2023 Feb; (): .
• 2023
  Trémeaux P, Lemoine F, Mélard A, Gousset M, Boufassa F, Orr S, Monceaux V, Gascuel O, Lambotte O, Hocqueloux L, Saez-Cirion A, Rouzioux C, Avettand-Fenoel V, , In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control., Microbiol Spectr 2023 Feb; 11(1): e0326722.
• 2023
  O'Doherty U, Martinez-Picado J, Sáez-Cirión A, Highlights from the Inaugural HIV Reservoirs and Immune Control Conference, October 1st-4th 2023, Malahide Ireland., Pathog Immun 2023 ; 8(1): 161-169.
• 2022
  Mausoléo A, Olivo A, Desjardins D, Sáez-Cirión A, Barrail-Tran A, Avettand-Fenoel V, Noël N, Lagathu C, Béréziat V, Le Grand R, Lambotte O, Bourgeois C, , Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques., Cells 2022 Oct; 11(19): .
• 2022
  Huyveneers LEP, Bruns A, Stam A, Ellerbroek P, de Jong D, Nagy NA, Gumbs SBH, Tesselaar K, Bosman K, Salgado M, Hütter G, Brosens LAA, Kwon M, Diez Martin J, van der Meer JTM, de Kort TM, Sáez-Cirión A, Schulze Zur Wiesch J, Boelens JJ, Martinez-Picado J, Kuball JHE, Wensing AMJ, Nijhuis M, , , Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells., Viruses 2022 09; 14(9): .
• 2022
  Rascle P, Planchais C, Jacquelin B, Lazzerini M, Contreras V, Passaes C, Saez-Cirion A, Mouquet H, Huot N, Müller-Trutwin M, , NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections., Commun Biol 2022 Jul; 5(1): 674.
• 2022
  Verdikt R, Bendoumou M, Bouchat S, Nestola L, Pasternak AO, Darcis G, Avettand-Fenoel V, Vanhulle C, Aït-Ammar A, Santangelo M, Plant E, Douce VL, Delacourt N, Cicilionytė A, Necsoi C, Corazza F, Passaes CPB, Schwartz C, Bizet M, Fuks F, Sáez-Cirión A, Rouzioux C, De Wit S, Berkhout B, Gautier V, Rohr O, Van Lint C, , Novel role of UHRF1 in the epigenetic repression of the latent HIV-1., EBioMedicine 2022 Apr; 79(): 103985.
• 2022
  Molinos-Albert LM, Lorin V, Monceaux V, Orr S, Essat A, Dufloo J, Schwartz O, Rouzioux C, Meyer L, Hocqueloux L, Sáez-Cirión A, Mouquet H, , , Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers., Nat Commun 2022 Apr; 13(1): 1944.
• 2022
  Perdomo-Celis F, Passaes C, Monceaux V, Volant S, Boufassa F, de Truchis P, Marcou M, Bourdic K, Weiss L, Jung C, Bourgeois C, Goujard C, Meyer L, Müller-Trutwin M, Lambotte O, Sáez-Cirión A, , Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control., J Clin Invest 2022 06; 132(11): .
• 2022
  Lemaitre J, Desjardins D, Gallouët AS, Gomez-Pacheco M, Bourgeois C, Favier B, Sáez-Cirión A, Le Grand R, Lambotte O, , Expansion of Immature Neutrophils During SIV Infection Is Associated With Their Capacity to Modulate T-Cell Function., Front Immunol 2022 ; 13(): 781356.
• 2021
  Plaçais L, Boufassa F, Lécuroux C, Gardiennet E, Avettand-Fenoel V, Saez-Cirion A, Lambotte O, Noël N, , , Antiretroviral therapy for HIV controllers: Reasons for initiation and outcomes in the French ANRS-CO21 CODEX cohort., EClinicalMedicine 2021 Jul; 37(): 100963.
• 2021
  Passaes C, Delagreverie HM, Avettand-Fenoel V, David A, Monceaux V, Essat A, Müller-Trutwin M, Duffy D, De Castro N, Wittkop L, Rouzioux C, Molina JM, Meyer L, Delaugerre C, Sáez-Cirión A, , Ultrasensitive Detection of p24 in Plasma Samples from People with Primary and Chronic HIV-1 Infection., J Virol 2021 06; 95(14): e0001621.
• 2021
  Huot N, Rascle P, Petitdemange C, Contreras V, Stürzel CM, Baquero E, Harper JL, Passaes C, Legendre R, Varet H, Madec Y, Sauermann U, Stahl-Hennig C, Nattermann J, Saez-Cirion A, Le Grand R, Keith Reeves R, Paiardini M, Kirchhoff F, Jacquelin B, Müller-Trutwin M, , SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity., Nat Commun 2021 02; 12(1): 1282.
• 2021
  Sáez-Cirión A, Sereti I, , Immunometabolism and HIV-1 pathogenesis: food for thought., Nat. Rev. Immunol. 2021 Jan;21(1):5-19.
• 2021
  Huot N, Rascle P, Planchais C, Contreras V, Passaes C, Le Grand R, Beignon AS, Kornobis E, Legendre R, Varet H, Saez-Cirion A, Mouquet H, Jacquelin B, Müller-Trutwin M, , CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues., Front Immunol 2021 ; 12(): 695148.
• 2020
  Passaes C, Millet A, Madelain V, Monceaux V, David A, Versmisse P, Sylla N, Gostick E, Llewellyn-Lacey S, Price DA, Blancher A, Dereuddre-Bosquet N, Desjardins D, Pancino G, Le Grand R, Lambotte O, Müller-Trutwin M, Rouzioux C, Guedj J, Avettand-Fenoel V, Vaslin B, Sáez-Cirión A, , Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study., Cell Rep 2020 09; 32(12): 108174.
• 2020
  Rujas E, Insausti S, Leaman DP, Carravilla P, González-Resines S, Monceaux V, Sánchez-Eugenia R, García-Porras M, Iloro I, Zhang L, Elortza F, Julien JP, Saéz-Cirión A, Zwick MB, Eggeling C, Ojida A, Domene C, Caaveiro JMM, Nieva JL, , Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments., Cell Rep 2020 Aug; 32(7): 108037.
• 2020
  Moron-Lopez S, Urrea V, Dalmau J, Lopez M, Puertas MC, Ouchi D, Gómez A, Passaes C, Mothe B, Brander C, Saez-Cirion A, Clotet B, Esteller M, Berdasco M, Martinez-Picado J, , The genome-wide methylation profile of CD4+ T cells from HIV-infected individuals identifies distinct patterns associated with disease progression., Clin Infect Dis 2020 Jul; (): .
• 2020
  Mikhailova A, Valle-Casuso JC, David A, Monceaux V, Volant S, Passaes C, Elfidha A, Müller-Trutwin M, Poyet JL, Sáez-Cirión A, , Antiapoptotic Clone 11-Derived Peptides Induce In Vitro Death of CD4+ T Cells Susceptible to HIV-1 Infection., J Virol 2020 07; 94(14): .
• 2020
  Gálvez C, Urrea V, Dalmau J, Jimenez M, Clotet B, Monceaux V, Huot N, Leal L, González-Soler V, González-Cao M, Müller-Trutwin M, Sáez-Cirión A, García F, Blanco J, Martinez-Picado J, Salgado M, , Extremely low viral reservoir in treated chronically HIV-1-infected individuals., EBioMedicine 2020 Jul; 57(): 102830.
• 2020
  Allouch A, Di Primio C, Paoletti A, Lê-Bury G, Subra F, Quercioli V, Nardacci R, David A, Saïdi H, Cereseto A, Ojcius DM, Montagnac G, Niedergang F, Pancino G, Saez-Cirion A, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL, , SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends., Cell Death Differ. 2020 Jun; (): .
• 2020
  Eberhard JM, Angin M, Passaes C, Salgado M, Monceaux V, Knops E, Kobbe G, Jensen B, Christopeit M, Kröger N, Vandekerckhove L, Badiola J, Bandera A, Raj K, van Lunzen J, Hütter G, Kuball JHE, Martinez-Laperche C, Balsalobre P, Kwon M, Díez-Martín JL, Nijhuis M, Wensing A, Martinez-Picado J, Schulze Zur Wiesch J, Sáez-Cirión A, , Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1., Sci Transl Med 2020 05; 12(542): .
• 2019
  Noël N, Saez-Cirion A, Avettand-Fenoël V, Boufassa F, Lambotte O, HIV controllers: to treat or not to treat? Is that the right question?, Lancet HIV 2019 Oct;.
• 2019
  Henriquez S, Lecuroux C, Bitu M, Avettand-Fenoel V, Churaqui F, Catalan P, Cheret A, Boufassa F, Saez-Cirion A, Monceaux V, Meyer L, Goujard C, Lambotte O, Bourgeois C, , The proportion of CD57+ cells among effector CD8+ T cells is lower HIV controllers compared to ART treated patients, AIDS 2019 Aug;.
• 2019
  Angin M, Volant S, Passaes C, Lecuroux C, Monceaux V, Dillies MA, Valle-Casuso JC, Pancino G, Vaslin B, Le Grand R, Weiss L, Goujard C, Meyer L, Boufassa F, Müller-Trutwin M, Lambotte O, Sáez-Cirión A, , Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection., Nat Metab 2019 07; 1(7): 704-716.
• 2019
  Saez-Cirion A, Müller-Trutwin M, , The Yellow Brick Road towards HIV Eradication., Trends Immunol 2019 06; 40(6): 465-467.
• 2019
  Hocini H, Bonnabau H, Lacabaratz C, Lefebvre C, Tisserand P, Foucat E, Lelièvre JD, Lambotte O, Saez-Cirion A, Versmisse P, Thiébaut R, Lévy Y, HIV Controllers Have Low Inflammation Associated with a Strong HIV-Specific Immune Response in Blood, J. Virol. 2019 May;93(10).
• 2019
  Valle-Casuso JC, Angin M, Volant S, Passaes C, Monceaux V, Mikhailova A, Bourdic K, Avettand-Fenoel V, Boufassa F, Sitbon M, Lambotte O, Thoulouze MI, Müller-Trutwin M, Chomont N, Sáez-Cirión A, , Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection., Cell Metab 2019 03; 29(3): 611-626.e5.
• 2019
  Delville M, Touzot F, Couzin C, Hmitou I, Djerroudi L, Ouedrani A, Lefrère F, Tuchman-Durand C, Mollet C, Fabreguettes JR, Ferry N, Laganier L, Magnani A, Magrin E, Jolaine V, Saez-Cirion A, Wolstein O, Symonds G, Frange P, Moins-Teisserenc H, Chaix-Baudier ML, Toubert A, Larghero J, Parquet N, Brignier AC, Barré-Sinoussi F, Oksenhendler E, Cavazzana M, Safety of CD34 Hematopoietic Stem Cells and CD4 T Lymphocytes Transduced with LVsh5/C46 in HIV-1 Infected Patients with High-Risk Lymphoma, Mol Ther Methods Clin Dev 2019 Jun;13:303-309.
• 2019
  Avettand-Fenoel V, Bayan T, Gardiennet E, Boufassa F, Lopez P, Lecuroux C, Noel N, Trémeaux P, Monceaux V, Autran B, Meyer L, Saez-Cirion A, Lambotte O, Rouzioux C, , Dynamics in HIV-DNA levels over time in HIV controllers, J Int AIDS Soc 2019 Jan;22(1):e25221.
• 2018
  Saez-Cirion A, Manel N, Immune Responses to Retroviruses, Annu. Rev. Immunol. 2018 Jan;.
• 2018
  Mikhailova A, Valle-Casuso JC, Sáez-Cirión A, Cellular Determinants of HIV Persistence on Antiretroviral Therapy, Adv. Exp. Med. Biol. 2018;1075:213-239.
• 2017
  Leitman EM, Palmer CD, Buus S, Chen F, Riddell L, Sims S, Klenerman P, Sáez-Cirión A, Walker BD, Hess PR, Altfeld M, Matthews PC, Goulder PJR, Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities, PLoS ONE 2017;12(10):e0184496.
• 2017
  Leitman EM, Willberg CB, Tsai MH, Chen H, Buus S, Chen F, Riddell L, Haas D, Fellay J, Goedert JJ, Piechocka-Trocha A, Walker BD, Martin J, Deeks S, Wolinsky SM, Martinson J, Martin M, Qi Y, Sáez-Cirión A, Yang OO, Matthews PC, Carrington M, Goulder PJR, HLA-B*14:02-RESTRICTED ENV-SPECIFIC CD8+ T-CELL ACTIVITY HAS HIGHLY POTENT ANTIVIRAL EFFICACY ASSOCIATED WITH IMMUNE CONTROL OF HIV INFECTION, J. Virol. 2017 Sep;.
• 2017
  Rutstein SE, Ananworanich J, Fidler S, Johnson C, Sanders EJ, Sued O, Saez-Cirion A, Pilcher CD, Fraser C, Cohen MS, Vitoria M, Doherty M, Tucker JD, Clinical and public health implications of acute and early HIV detection and treatment: a scoping review, J Int AIDS Soc 2017 Jun;20(1):1-13.
• 2017
  Canouï E, Lécuroux C, Avettand-Fenoël V, Gousset M, Rouzioux C, Saez-Cirion A, Meyer L, Boufassa F, Lambotte O, Noël N,, A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level, Open Forum Infect Dis 2017;4(2):ofx064.
• 2017
  Passaes CPB, Bruel T, Decalf J, David A, Angin M, Monceaux V, Muller-Trutwin M, Noel N, Bourdic K, Lambotte O, Albert ML, Duffy D, Schwartz O, Sáez-Cirión A, , Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents., J Virol 2017 03; 91(6): .
• 2016
  Samri A, Bacchus-Souffan C, Hocqueloux L, Avettand-Fenoel V, Descours B, Theodorou I, Larsen M, Saez-Cirion A, Rouzioux C, Autran B, , Polyfunctional HIV-specific T cells in Post-Treatment Controllers, AIDS 2016 Sep;30(15):2299-302.
• 2016
  Angin M, Wong G, Papagno L, Versmisse P, David A, Bayard C, Muylder BC, Besseghir A, Thiébaut R, Boufassa F, Pancino G, Sauce D, Lambotte O, Brun-Vézinet F, Matheron S, Rowland-Jones SL, Cheynier R, Sáez-Cirión A, Appay V,, Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers, J. Immunol. 2016 Aug;.
• 2016
  Canoui E, Noël N, Lécuroux C, Boufassa F, Sáez-Cirión A, Bourgeois C, Lambotte O, , Strong Ifitm1 Expression In Cd4 T Cells In Hiv Controllers Is Correlated With Immune Activation, J. Acquir. Immune Defic. Syndr. 2016 Aug;.
• 2016
  Ploquin MJ, Madec Y, Casrouge A, Huot N, Passaes C, Lécuroux C, Essat A, Boufassa F, Jacquelin B, Jochems SP, Petitjean G, Angin M, Gärtner K, Garcia-Tellez T, Noël N, Booiman T, Boeser-Nunnink BD, Roques P, Saez-Cirion A, Vaslin B, Dereudre-Bosquet N, Barré-Sinoussi F, Ghislain M, Rouzioux C, Lambotte O, Albert ML, Goujard C, Kootstra N, Meyer L, Müller-Trutwin MC, , Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset., PLoS Pathog 2016 08; 12(8): e1005774.
• 2016
  Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, Barre-Sinoussi F, , Alter G, Auerbach J, Autran B, Barouch DH, Behrens G, Cavazzana M, Chen Z, Cohen ÉA, Corbelli GM, Eholié S, Eyal N, Fidler S, Garcia L, Grossman C, Henderson G, Henrich TJ, Jefferys R, Kiem HP, McCune J, Moodley K, Newman PA, Nijhuis M, Nsubuga MS, Ott M, Palmer S, Richman D, Saez-Cirion A, Sharp M, Siliciano J, Silvestri G, Singh J, Spire B, Taylor J, Tolstrup M, Valente S, van Lunzen J, Walensky R, Wilson I, Zack J, International AIDS Society global scientific strategy: towards an HIV cure 2016, Nat. Med. 2016 Jul;.
• 2016
  Noel N, Peña R, David A, Avettand-Fenoel V, Erkizia I, Jimenez E, Lecuroux C, Rouzioux C, Boufassa F, Pancino G, Venet A, Van Lint C, Martinez-Picado J, Lambotte O, Sáez-Cirión A, Prado JG,, Long-term Spontaneous control of HIV-1 relates to low frequency of infected cells and inefficient viral reactivation, J. Virol. 2016 Apr; 90(13):6148-58.
• 2016
  Hamimi C, David A, Versmisse P, Weiss L, Bruel T, Zucman D, Appay V, Moris A, Ungeheuer MN, Lascoux-Combe C, Barré-Sinoussi F, Muller-Trutwin M, Boufassa F, Lambotte O, Pancino G, Sáez-Cirión A, , , Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles., PLoS One 2016 ; 11(8): e0160251.
• 2015
  Frange P, Faye A, Avettand-Fenoël V, Bellaton E, Descamps D, Angin M, David A, Caillat-Zucman S, Peytavin G, Dollfus C, Le Chenadec J, Warszawski J, Rouzioux C, Sáez-Cirión A, , HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report, Lancet HIV 2016 Jan;3(1):e49-54.
• 2015
  Noel N, Lerolle N, Lécuroux C, Goujard C, Venet A, Saez-Cirion A, Avettand-Fenoël V, Meyer L, Boufassa F, Lambotte O, , Immunologic and Virologic Progression in HIV Controllers: The Role of Viral “Blips” and Immune Activation in the ANRS CO21 CODEX Study, PLoS ONE 2015;10(7):e0131922.
• 2015
  Chéret A, Bacchus-Souffan C, Avettand-Fenoël V, Mélard A, Nembot G, Blanc C, Samri A, Sáez-Cirión A, Hocqueloux L, Lascoux-Combe C, Allavena C, Goujard C, Valantin MA, Leplatois A, Meyer L, Rouzioux C, Autran B, , Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission, J. Antimicrob. Chemother. 2015 Jul;70(7):2108-20.
• 2015
  Chéret A, Nembot G, Mélard A, Lascoux C, Slama L, Miailhes P, Yeni P, Abel S, Avettand-Fenoel V, Venet A, Chaix ML, Molina JM, Katlama C, Goujard C, Tamalet C, Raffi F, Lafeuillade A, Reynes J, Ravaux I, Hoën B, Delfraissy JF, Meyer L, Rouzioux C, , Intensive five-drug antiretroviral therapy regimen versus standard triple-drug therapy during primary HIV-1 infection (OPTIPRIM-ANRS 147): a randomised, open-label, phase 3 trial, Lancet Infect Dis 2015 Apr;15(4):387-96.
• 2015
  Bruel T, Hamimi C, Dereuddre-Bosquet N, Cosma A, Shin SY, Corneau A, Versmisse P, Karlsson I, Malleret B, Targat B, Barré-Sinoussi F, Le Grand R, Pancino G, Sáez-Cirión A, Vaslin B, Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses, J. Virol. 2015 Apr;89(7):3542-56.
• 2015
  Wilflingseder D, Schroll A, Hackl H, Gallasch R, Frampton D, Lass-Flörl C, Pancino G, Saez-Cirion A, Lambotte O, Weiss L, Kellam P, Trajanoski Z, Geijtenbeek T, Weiss G, Posch W, Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells, J. Infect. Dis. 2015 Jul;212(1):44-56.
• 2015
  Rouzioux C, Hocqueloux L, Sáez-Cirión A, Posttreatment controllers: what do they tell us?, Curr Opin HIV AIDS 2015 Jan;10(1):29-34.
• 2014
  Simonetta F, Hua S, Lécuroux C, Gérard S, Boufassa F, Sáez-Cirión A, Pancino G, Goujard C, Lambotte O, Venet A, Bourgeois C, High eomesodermin expression among CD57+ CD8+ T cells identifies a CD8+ T cell subset associated with viral control during chronic human immunodeficiency virus infection, J. Virol. 2014 Oct;88(20):11861-71.
• 2014
  Hua S, Lécuroux C, Sáez-Cirión A, Pancino G, Girault I, Versmisse P, Boufassa F, Taulera O, Sinet M, Lambotte O, Venet A, Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers, PLoS ONE 2014;9(7):e101920.
• 2014
  Allouch A, David A, Amie SM, Lahouassa H, Chartier L, Margottin-Goguet F, Barré-Sinoussi F, Kim B, Sáez-Cirión A, Pancino G, Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block, Proc. Natl. Acad. Sci. U.S.A. 2014 Apr;111(14):E1325-6.
• 2014
  Passaes CP, Sáez-Cirión A, , HIV cure research: advances and prospects., Virology 2014 Apr; 454-455(): 340-52.
• 2014
  Vanham G, Buvé A, Florence E, Seguin-Devaux C, Sáez-Cirión A, What is the significance of posttreatment control of HIV infection vis-à-vis functional cure?, AIDS 2014 Feb;28(4):603-5.
• 2014
  Lissina A, Fastenackels S, Inglesias MC, Ladell K, McLaren JE, Briceño O, Gostick E, Papagno L, Autran B, Sauce D, Price DA, Saez-Cirion A, Appay V, The link between CD8⁺ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate, AIDS 2014 Feb;28(4):477-86.
• 2014
  Noel N, Boufassa F, Lécuroux C, Saez-Cirion A, Bourgeois C, Dunyach-Remy C, Goujard C, Rouzioux C, Meyer L, Pancino G, Venet A, Lambotte O, , Elevated IP10 levels are associated with immune activation and low CD4⁺ T-cell counts in HIV controller patients, AIDS 2014 Feb;28(4):467-76.
• 2014
  Boufassa F, Lechenadec J, Meyer L, Costagliola D, Hunt PW, Pereyra F, Deeks S, Pancino G, Taulera O, Lichterfeld M, Delobel P, Saez-Cirion A, Lambotte O, , , , , Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration, PLoS ONE 2014;9(1):e85516.
• 2014
  Saez-Cirion A, Jacquelin B, Barré-Sinoussi F, Müller-Trutwin M, , Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?, Philos Trans R Soc Lond B Biol Sci 2014 ; 369(1645): 20130436.
• 2013
  Lécuroux C, Sáez-Cirión A, Girault I, Versmisse P, Boufassa F, Avettand-Fenoël V, Rouzioux C, Meyer L, Pancino G, Lambotte O, Sinet M, Venet A, Both HLA-B*57 and plasma HIV RNA levels contribute to the HIV-specific CD8+ T cell response in HIV controllers, J. Virol. 2014 Jan;88(1):176-87.
• 2013
  Allouch A, David A, Amie SM, Lahouassa H, Chartier L, Margottin-Goguet F, Barré-Sinoussi F, Kim B, Sáez-Cirión A, Pancino G, p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway, Proc. Natl. Acad. Sci. U.S.A. 2013 Oct;110(42):E3997-4006.
• 2013
  Lambotte O, Pollara J, Boufassa F, Moog C, Venet A, Haynes BF, Delfraissy JF, Saez-Cirion A, Ferrari G, High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers, PLoS ONE 2013;8(9):e74855.
• 2013
  Sáez-Cirión A, Pancino G, HIV controllers: a genetically determined or inducible phenotype?, Immunol. Rev. 2013 Jul;254(1):281-94.
• 2013
  Hamimi C, Pancino G, Barré-Sinoussi F, Sáez-Cirión A, Will it be possible to live without antiretroviral therapy?, Curr Opin HIV AIDS 2013 May;8(3):196-203.
• 2013
  Lécuroux C, Girault I, Chéret A, Versmisse P, Nembot G, Meyer L, Rouzioux C, Pancino G, Venet A, Sáez-Cirión A, , CD8 T-cells from most HIV-infected patients lack ex vivo HIV-suppressive capacity during acute and early infection, PLoS ONE 2013;8(3):e59767.
• 2013
  Hocqueloux L, Saez-Cirion A, Rouzioux C, Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion, JAMA Intern Med 2013 Mar;173(6):475-6.
• 2013
  Sáez-Cirión A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, Lecuroux C, Potard V, Versmisse P, Melard A, Prazuck T, Descours B, Guergnon J, Viard JP, Boufassa F, Lambotte O, Goujard C, Meyer L, Costagliola D, Venet A, Pancino G, Autran B, Rouzioux C, , Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study, PLoS Pathog. 2013 Mar;9(3):e1003211.
• 2013
  Lecuroux C, Saez-Cirion A, Noel N, Ben-Lamine L, Girault I, Caillat-Zucman S, Scott-Algara D, Venet A, Lambotte O, NKG2D expression on HIV-specific CD8+ T cells is reduced in viremic HIV-1-infected patients but maintained in HIV controllers, J. Acquir. Immune Defic. Syndr. 2013 Jan;62(1):17-20.
• 2012
  Iglesias MC, Briceno O, Gostick E, Moris A, Meaudre C, Price DA, Ungeheuer MN, Saez-Cirion A, Mallone R, Appay V, Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency, Immunol. Lett. 2013 Jan;149(1-2):119-22.
• 2012
  Posch W, Cardinaud S, Hamimi C, Fletcher A, Mühlbacher A, Loacker K, Eichberger P, Dierich MP, Pancino G, Lass-Flörl C, Moris A, Saez-Cirion A, Wilflingseder D, Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes, J. Allergy Clin. Immunol. 2012 Dec;130(6):1368-74.e2.
• 2012
  Lambotte O, Lecuroux C, Saez-Cirion A, Barbet C, Shin SY, Boufassa F, Bastides F, Lebranchu Y, Kidney transplantation in an elite HIV controller: limited impact of immunosuppressive therapy on viro-immunological status, J. Infect. 2012 Jun;64(6):630-3.
• 2011
  Sáez-Cirión A, Hamimi C, Bergamaschi A, David A, Versmisse P, Mélard A, Boufassa F, Barré-Sinoussi F, Lambotte O, Rouzioux C, Pancino G,, Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers, Blood 2011 Jul;118(4):955-64.
• 2011
  Boufassa F, Saez-Cirion A, Lechenadec J, Zucman D, Avettand-Fenoel V, Venet A, Rouzioux C, Delfraissy JF, Lambotte O, Meyer L, , CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory, PLoS ONE 2011;6(4):e18726.
• 2010
  Pancino G, Saez-Cirion A, Scott-Algara D, Paul P, Natural resistance to HIV infection: lessons learned from HIV‐exposed uninfected individuals, J. Infect. Dis. 2010 Nov;202 Suppl 3:S345-50.
• 2010
  Sáez-Cirión A, Shin SY, Versmisse P, Barré-Sinoussi F, Pancino G, Ex vivo T cell-based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses, Nat Protoc 2010 Jun;5(6):1033-41.
• 2009
  Sáez-Cirión A, Sinet M, Shin SY, Urrutia A, Versmisse P, Lacabaratz C, Boufassa F, Avettand-Fènoël V, Rouzioux C, Delfraissy JF, Barré-Sinoussi F, Lambotte O, Venet A, Pancino G, , Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses, J. Immunol. 2009 Jun;182(12):7828-37.
• 2009
  Almeida JR, Sauce D, Price DA, Papagno L, Shin SY, Moris A, Larsen M, Pancino G, Douek DC, Autran B, Sáez-Cirión A, Appay V, Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity, Blood 2009 Jun;113(25):6351-60.
• 2008
  Sáez-Cirión A, The characteristic CD8+ T cell response in HIV controllers: an objective to achieve?, Pathol. Biol. 2008 Jul;56(5):251-3.
• 2008
  Lorizate M, Huarte N, Sáez-Cirión A, Nieva JL, Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission, Biochim. Biophys. Acta 2008 Jul-Aug;1778(7-8):1624-39.
• 2007
  Sáez-Cirión A, Pancino G, Sinet M, Venet A, Lambotte O, , HIV controllers: how do they tame the virus?, Trends Immunol. 2007 Dec;28(12):532-40.
• 2007
  Masson C, Bury-Moné S, Guiot E, Saez-Cirion A, Schoëvaërt-Brossault D, Brachet-Ducos C, Delelis O, Subra F, Jeanson-Leh L, Mouscadet JF, Ku80 participates in the targeting of retroviral transgenes to the chromatin of CHO cells, J. Virol. 2007 Aug;81(15):7924-32.
• 2007
  Lamine A, Caumont-Sarcos A, Chaix ML, Saez-Cirion A, Rouzioux C, Delfraissy JF, Pancino G, Lambotte O, Replication-competent HIV strains infect HIV controllers despite undetectable viremia (ANRS EP36 study), AIDS 2007 May;21(8):1043-5.
• 2007
  Sáez-Cirión A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, Boufassa F, Barré-Sinoussi F, Delfraissy JF, Sinet M, Pancino G, Venet A,, HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype, Proc. Natl. Acad. Sci. U.S.A. 2007 Apr;104(16):6776-81.
• 2006
  Sáez-Cirión A, Versmisse P, Truong LX, Chakrabarti LA, Carpentier W, Barré-Sinoussi F, Scott-Algara D, Pancino G, Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks, Retrovirology 2006;3:81.
• 2006
  David A, Sáez-Cirión A, Versmisse P, Malbec O, Iannascoli B, Herschke F, Lucas M, Barré-Sinoussi F, Mouscadet JF, Daëron M, Pancino G, The engagement of activating FcgammaRs inhibits primate lentivirus replication in human macrophages, J. Immunol. 2006 Nov;177(9):6291-300.
• 2006
  Sáez-Cirión A, Nicola MA, Pancino G, Shorte SL, Quantitative real-time analysis of HIV-1 gene expression dynamics in single living primary cells, Biotechnol J 2006 Jun;1(6):682-9.
• 2005
  Menu E, Müller-Trutwin MC, Pancino G, Saez-Cirion A, Bain C, Inchauspé G, Gras GS, Mabondzo AM, Samri A, Boutboul F, Le Grand R, , First Dominique Dormont International Conference on “Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections”., Retrovirology 2005 Apr; 2(): 24.
• 2003
  Sáez-Cirión A, Arrondo JL, Gómara MJ, Lorizate M, Iloro I, Melikyan G, Nieva JL, Structural and functional roles of HIV-1 gp41 pretransmembrane sequence segmentation, Biophys. J. 2003 Dec;85(6):3769-80.
• 2003
  Sáez-Cirión A, Nieva JL, Gallaher WR, The hydrophobic internal region of bovine prion protein shares structural and functional properties with HIV type 1 fusion peptide, AIDS Res. Hum. Retroviruses 2003 Nov;19(11):969-78.
• 2003
  Sáez-Cirión A, Gómara MJ, Agirre A, Nieva JL, Pre-transmembrane sequence of Ebola glycoprotein. Interfacial hydrophobicity distribution and interaction with membranes, FEBS Lett. 2003 Jan;533(1-3):47-53.
• 2002
  Sáez-Cirión A, Nieva JL, Conformational transitions of membrane-bound HIV-1 fusion peptide, Biochim. Biophys. Acta 2002 Aug;1564(1):57-65.
• 2002
  Sáez-Cirión A, Nir S, Lorizate M, Agirre A, Cruz A, Pérez-Gil J, Nieva JL, Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring, J. Biol. Chem. 2002 Jun;277(24):21776-85.
• 2000
  Sáez-Cirión A, Basáñez G, Fidelio G, Goñi FM, Maggio B, Alonso A, Sphingolipids (Galactosylceramide and Sulfatide) in Lamellar−Hexagonal Phospholipid Phase Transitions and in Membrane Fusion, Langmuir, 2000, 16 (23), pp 8958–8963.
• 2000
  Suárez T, Nir S, Goñi FM, Saéz-Cirión A, Nieva JL, The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence, FEBS Lett. 2000 Jul;477(1-2):145-9.
• 2000
  Sáez-Cirión A, Alonso A, Goñi FM, McMullen TPW, McElhaney RN, Rivas EA, Equilibrium and Kinetic Studies of the Solubilization of Phospholipid−Cholesterol Bilayers by C12E8. The Influence of the Lipid Phase Structure, Langmuir, 2000, 16 (4), pp 1960–1968.