• 2018
  Oberkampf M, Guillerey C, Mouriès J, Rosenbaum P, Fayolle C, Bobard A, Savina A, Ogier-Denis E, Enninga J, Amigorena S, Leclerc C, Dadaglio G, Mitochondrial reactive oxygen species regulate the induction of CD8 T cells by plasmacytoid dendritic cells, Nat Commun 2018 Jun;9(1):2241.
• 2018
  Terra M, Oberkampf M, Fayolle C, Rosenbaum P, Guillerey C, Dadaglio G, Leclerc C, Tumor-Derived TGFβ Alters the Ability of Plasmacytoid Dendritic Cells to Respond to Innate Immune Signaling, Cancer Res. 2018 Jun;78(11):3014-3026.
• 2017
  Majlessi L, Sayes F, Bureau JF, Pawlik A, Michel V, Jouvion G, Huerre M, Severgnini M, Consolandi C, Peano C, Brosch R, Touati E, Leclerc C, Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis, Mucosal Immunol 2017 Sep;10(5):1178-1189.
• 2017
  Christelle Ganneau, Catherine Simenel, Emeline Emptas, Tiphanie Courtiol, Yves-Marie Coïc, Cécile Artaud, Edith Dériaud, Frédéric Bonhomme, Muriel Delepierre, Claude Leclerc, Richard Lo-Man and Sylvie Bay, Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Organic & Biomolecular Chemistry, 2017, 15, 114 - 123.
• 2016
  Bernelin-Cottet C, Deloizy C, Stanek O, Barc C, Bouguyon E, Urien C, Boulesteix O, Pezant J, Richard CA, Moudjou M, Da Costa B, Jouneau L, Chevalier C, Leclerc C, Sebo P, Bertho N, Schwartz-Cornil I, A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies, Front Immunol 2016;7:641.
• 2016
  Ganneau C, Simenel C, Emptas E, Courtiol T, Coïc YM, Artaud C, Dériaud E, Bonhomme F, Delepierre M, Leclerc C, Lo-Man R, Bay S, Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Org. Biomol. Chem. 2016 Dec;15(1):114-123.
• 2016
  Sayes F, Pawlik A, Frigui W, Gröschel MI, Crommelynck S, Fayolle C, Cia F, Bancroft GJ, Bottai D, Leclerc C, Brosch R, Majlessi L., CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection, PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770..
• 2016
  Tang A, Dadaglio G, Oberkampf M, Di Carlo S, Peduto L, Laubreton D, Desrues B, Sun CM, Montagutelli X, Leclerc C, B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer, Int. J. Cancer 2016 Sep;139(6):1358-71.
• 2016
  Laubreton D, Bay S, Sedlik C, Artaud C, Ganneau C, Dériaud E, Viel S, Puaux AL, Amigorena S, Gérard C, Lo-Man R, Leclerc C, , The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity., Cancer Immunol Immunother 2016 Mar; 65(3): 315-25.
• 2015
  Coelho H, Matsushita T, Artigas G, Hinou H, Cañada FJ, Lo-Man R, Leclerc C, Cabrita EJ, Jiménez-Barbero J, Nishimura S, Garcia-Martín F, Marcelo F, The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR, J. Am. Chem. Soc. 2015 Oct;137(39):12438-41.
• 2015
  Chaoul N, Fayolle C, Desrues B, Oberkampf M, Tang A, Ladant D, Leclerc C, Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication, Cancer Res. 2015 Aug;75(16):3279-91.
• 2015
  Lemoine S, Jaron B, Tabka S, Ettreiki C, Deriaud E, Zhivaki D, Le Ray C, Launay O, Majlessi L, Tissieres P, Leclerc C, Lo-Man R, Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells, J. Allergy Clin. Immunol. 2015 Nov;136(5):1355-1368.e15.
• 2014
  Daleke-Schermerhorn MH, Felix T, Soprova Z, Ten Hagen-Jongman CM, Vikström D, Majlessi L, Beskers J, Follmann F, de Punder K, van der Wel NN, Baumgarten T, Pham TV, Piersma SR, Jiménez CR, van Ulsen P, de Gier JW, Leclerc C, Jong WS, Luirink J, Decoration of outer membrane vesicles with multiple antigens by using an autotransporter approach, Appl. Environ. Microbiol. 2014 Sep;80(18):5854-65.
• 2014
  Dadaglio G, Fayolle C, Zhang X, Ryffel B, Oberkampf M, Felix T, Hervas-Stubbs S, Osicka R, Sebo P, Ladant D, Leclerc C, Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses, J. Immunol. 2014 Aug;193(4):1787-98.
• 2014
  Hervas-Stubbs S, Riezu-Boj JI, Mancheño U, Rueda P, Lopez L, Alignani D, Rodríguez-García E, Thieblemont N, Leclerc C, Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming, J. Immunol. 2014 Aug;193(3):1151-61.
• 2014
  Zhang X, Mozeleski B, Lemoine S, Dériaud E, Lim A, Zhivaki D, Azria E, Le Ray C, Roguet G, Launay O, Vanet A, Leclerc C, Lo-Man R, CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus, Sci Transl Med 2014 May;6(238):238ra72.
• 2014
  Zhang X, Casartelli N, Lemoine S, Mozeleski B, Azria E, Le Ray C, Schwartz O, Launay O, Leclerc C, Lo-Man R, Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings, J. Infect. Dis. 2014 Aug;210(3):424-34.
• 2013
  van Vliet SJ, Bay S, Vuist IM, Kalay H, García-Vallejo JJ, Leclerc C, van Kooyk Y, MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion, J. Leukoc. Biol. 2013 Aug;94(2):315-23.
• 2013
  Mazal D, Lo-Man R, Bay S, Pritsch O, Dériaud E, Ganneau C, Medeiros A, Ubillos L, Obal G, Berois N, Bollati-Fogolin M, Leclerc C, Osinaga E, Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer, Cancer Immunol. Immunother. 2013 Jun;62(6):1107-22.
• 2013
  Zhang X, Lepelley A, Azria E, Lebon P, Roguet G, Schwartz O, Launay O, Leclerc C, Lo-Man R, Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses, PLoS ONE 2013;8(1):e52003.
• 2013
  Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Médigue C, Parkhill J, Cruveiller S, Brosch R, Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis, Nat. Genet. 2013 Feb;45(2):172-9.
• 2012
  Stanek O, Linhartova I, Majlessi L, Leclerc C, Sebo P, Complexes of streptavidin-fused antigens with biotinylated antibodies targeting receptors on dendritic cell surface: a novel tool for induction of specific T-cell immune responses, Mol. Biotechnol. 2012 Jul;51(3):221-32.
• 2012
  Guillerey C, Mouriès J, Polo G, Doyen N, Law HK, Chan S, Kastner P, Leclerc C, Dadaglio G, Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice, Blood 2012 Jul;120(1):90-9.
• 2012
  Sainz-Perez A, Lim A, Lemercier B, Leclerc C, The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences, Cancer Res. 2012 Jul;72(14):3557-69.
• 2012
  Sayes F, Sun L, Di Luca M, Simeone R, Degaiffier N, Fiette L, Esin S, Brosch R, Bottai D, Leclerc C, Majlessi L, Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential, Cell Host Microbe 2012 Apr;11(4):352-63.
• 2012
  Fiser R, Masin J, Bumba L, Pospisilova E, Fayolle C, Basler M, Sadilkova L, Adkins I, Kamanova J, Cerny J, Konopasek I, Osicka R, Leclerc C, Sebo P, Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores, PLoS Pathog. 2012;8(4):e1002580.
• 2012
  Rudilla F, Fayolle C, Casares N, Durantez M, Arribillaga L, Lozano T, Villanueva L, Pio R, Sarobe P, Leclerc C, Prieto J, Lasarte JJ, Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses, Vaccine 2012 Apr;30(18):2848-58.
• 2012
  Bottai D, Di Luca M, Majlessi L, Frigui W, Simeone R, Sayes F, Bitter W, Brennan MJ, Leclerc C, Batoni G, Campa M, Brosch R, Esin S, Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation, Mol. Microbiol. 2012 Mar;83(6):1195-209.
• 2012
  Mohr S, Borras L, Nolan J, Gillieron C, Brandt PY, Eytan A, Leclerc C, Perroud N, Whetten K, Pieper C, Koenig HG, Huguelet P, Spirituality and religion in outpatients with schizophrenia: a multi-site comparative study of Switzerland, Canada, and the United States, Int J Psychiatry Med 2012;44(1):29-52.
• 2011
  Beauchamp MC, Lecomte T, Lecomte C, Leclerc C, Corbière M, Do personality traits matter when choosing a group therapy for early psychosis?, Psychol Psychother 2013 Mar;86(1):19-32.
• 2011
  Mansilla C, Berraondo P, Durantez M, Martínez M, Casares N, Arribillaga L, Rudilla F, Fioravanti J, Lozano T, Villanueva L, Sarobe P, Borrás F, Leclerc C, Prieto J, Lasarte JJ, Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin, Int. J. Cancer 2012 Aug;131(3):641-51.
• 2011
  Olivier A, Sainz-Perez A, Dong H, Sparwasser T, Majlessi L, Leclerc C, The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells, Eur. J. Immunol. 2011 Aug;41(8):2303-13.
• 2011
  Bottai D, Majlessi L, Simeone R, Frigui W, Laurent C, Lenormand P, Chen J, Rosenkrands I, Huerre M, Leclerc C, Cole ST, Brosch R, ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis, J. Infect. Dis. 2011 Apr;203(8):1155-64.
• 2011
  Cloutier L, Leclerc C, [Evaluation of the mental condition. How are you today?], Perspect Infirm 2011 Mar-Apr;8(2):29-31.
• 2010
  Freire T, Lo-Man R, Bay S, Leclerc C, Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses, J. Biol. Chem. 2011 Mar;286(10):7797-811.
• 2010
  Durantez M, Fayolle C, Casares N, Belsue V, Riezu-Boj JI, Sarobe P, Prieto J, Borrás-Cuesta F, Leclerc C, Lasarte JJ, Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis, Vaccine 2010 Oct;28(44):7146-54.
• 2010
  Fayolle C, Davi M, Dong H, Ritzel D, Le Page A, Knipping F, Majlessi L, Ladant D, Leclerc C, Induction of anti-Tat neutralizing antibodies by the CyaA vector targeting dendritic cells: influence of the insertion site and of the delivery of multicopies of the dominant Tat B-cell epitope, Vaccine 2010 Oct;28(42):6930-41.
• 2010
  Freire T, Zhang X, Dériaud E, Ganneau C, Vichier-Guerre S, Azria E, Launay O, Lo-Man R, Bay S, Leclerc C, Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant, Blood 2010 Nov;116(18):3526-36.
• 2010
  Beauchamp MC, Lecomte T, Lecomte C, Leclerc C, Corbière M, Personality traits in early psychosis: relationship with symptom and coping treatment outcomes, Early Interv Psychiatry 2011 Feb;5(1):33-40.
• 2010
  Noiseux S, Tribble St-Cyr D, Corin E, St-Hilaire PL, Morissette R, Leclerc C, Fleury D, Vigneault L, Gagnier F, The process of recovery of people with mental illness: the perspectives of patients, family members and care providers: part 1, BMC Health Serv Res 2010;10:161.
• 2010
  Leclerc C, Towards a rational approach to vaccine development, Hum Vaccin 2010 Apr;6(4):292-6.
• 2010
  Osickova A, Masin J, Fayolle C, Krusek J, Basler M, Pospisilova E, Leclerc C, Osicka R, Sebo P, Adenylate cyclase toxin translocates across target cell membrane without forming a pore, Mol. Microbiol. 2010 Mar;75(6):1550-62.
• 2009
  Zhang X, Majlessi L, Deriaud E, Leclerc C, Lo-Man R, Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils, Immunity 2009 Nov;31(5):761-71.
• 2009
  Woodward TS, Munz M, LeClerc C, Lecomte T, Change in delusions is associated with change in “jumping to conclusions”, Psychiatry Res 2009 Dec;170(2-3):124-7.
• 2009
  Borras L, Mohr S, Gillieron C, Brandt PY, Rieben I, Leclerc C, Huguelet P, Religion and spirituality: how clinicians in quebec and geneva cope with the issue when faced with patients suffering from chronic psychosis, Community Ment Health J 2010 Feb;46(1):77-86.
• 2009
  Terme M, Mignot G, Ullrich E, Bonmort M, Minard-Colin V, Jacquet A, Schultze JL, Kroemer G, Leclerc C, Chaput N, Zitvogel L, The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells, Cancer Res. 2009 Aug;69(16):6590-7.
• 2009
  Noiseux S, St-Cyr Tribble D, Leclerc C, Ricard N, Corin E, Morissette R, Lambert R, Developing a model of recovery in mental health, BMC Health Serv Res 2009;9:73.
• 2008
  Lecomte T, Leclerc C, Corbière M, Wykes T, Wallace CJ, Spidel A, Group cognitive behavior therapy or social skills training for individuals with a recent onset of psychosis? Results of a randomized controlled trial, J. Nerv. Ment. Dis. 2008 Dec;196(12):866-75.
• 2008
  Leclerc C, Brose C, Nouzé C, Leonard F, Majlessi L, Becker S, von Briesen H, Lo-Man R, Immobilized cytokines as biomaterials for manufacturing immune cell based vaccines, J Biomed Mater Res A 2008 Sep;86(4):1033-40.
• 2008
  Mouriès J, Moron G, Schlecht G, Escriou N, Dadaglio G, Leclerc C, Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation, Blood 2008 Nov;112(9):3713-22.
• 2008
  Jaron B, Maranghi E, Leclerc C, Majlessi L, Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis, PLoS ONE 2008;3(7):e2833.
• 2008
  Majlessi L, Lo-Man R, Leclerc C, Regulatory B and T cells in infections, Microbes Infect. 2008 Jul;10(9):1030-5.
• 2008
  Doré G, Leclerc C, Lazarini F, Treatment by CpG or Flt3-ligand does not affect mouse susceptibility to BSE prions, J. Neuroimmunol. 2008 Jun;197(1):74-80.
• 2008
  Lecomte T, Spidel A, Leclerc C, MacEwan GW, Greaves C, Bentall RP, Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis, Schizophr. Res. 2008 Jul;102(1-3):295-302.
• 2008
  Frigui W, Bottai D, Majlessi L, Monot M, Josselin E, Brodin P, Garnier T, Gicquel B, Martin C, Leclerc C, Cole ST, Brosch R, Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP, PLoS Pathog. 2008 Feb;4(2):e33.
• 2007
  Berraondo P, Nouzé C, Préville X, Ladant D, Leclerc C, Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system, Cancer Res. 2007 Sep;67(18):8847-55.
• 2007
  Couture S, Lecomte T, Leclerc C, Personality characteristics and attachment in first episode psychosis: impact on social functioning, J. Nerv. Ment. Dis. 2007 Aug;195(8):631-9.
• 2007
  Majlessi L, Combaluzier B, Albrecht I, Garcia JE, Nouze C, Pieters J, Leclerc C, Inhibition of phagosome maturation by mycobacteria does not interfere with presentation of mycobacterial antigens by MHC molecules, J. Immunol. 2007 Aug;179(3):1825-33.
• 2007
  Connell TG, Shey MS, Seldon R, Rangaka MX, van Cutsem G, Simsova M, Marcekova Z, Sebo P, Curtis N, Diwakar L, Meintjes GA, Leclerc C, Wilkinson RJ, Wilkinson KA, Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector, Clin. Vaccine Immunol. 2007 Jul;14(7):847-54.
• 2007
  Zhang X, Deriaud E, Jiao X, Braun D, Leclerc C, Lo-Man R, Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells, J. Exp. Med. 2007 May;204(5):1107-18.
• 2007
  Leclerc C, [New technologies for vaccine development], Med Sci (Paris) 2007 Apr;23(4):386-90.
• 2007
  Hervas-Stubbs S, Olivier A, Boisgerault F, Thieblemont N, Leclerc C, TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help, Blood 2007 Jun;109(12):5318-26.
• 2007
  Stip E, Corbière M, Boulay LJ, Lesage A, Lecomte T, Leclerc C, Ricard N, Cyr M, Guillem F, Intrusion errors in explicit memory: their differential relationship with clinical and social outcome in chronic schizophrenia, Cogn Neuropsychiatry 2007 Mar;12(2):112-27.
• 2007
  Hervas-Stubbs S, Rueda P, Lopez L, Leclerc C, Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN, J. Immunol. 2007 Feb;178(4):2361-9.
• 2007
  Lasarte JJ, Casares N, Gorraiz M, Hervás-Stubbs S, Arribillaga L, Mansilla C, Durantez M, Llopiz D, Sarobe P, Borrás-Cuesta F, Prieto J, Leclerc C, The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo, J. Immunol. 2007 Jan;178(2):748-56.
• 2006
  Freire T, Bay S, Vichier-Guerre S, Lo-Man R, Leclerc C, Carbohydrate antigens: synthesis aspects and immunological applications in cancer, Mini Rev Med Chem 2006 Dec;6(12):1357-73.
• 2006
  Pan ZM, Zhang XM, Jiao XA, Lo-Man R, Leclerc C, Liu XF, [Analysis of in vitro delivering CD8+ T epitopes by attenuated bacteria], Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006 Nov;22(6):730-3.
• 2006
  Bertrand JY, Desanti GE, Lo-Man R, Leclerc C, Cumano A, Golub R, Fetal spleen stroma drives macrophage commitment, Development 2006 Sep;133(18):3619-28.
• 2006
  Hervas-Stubbs S, Majlessi L, Simsova M, Morova J, Rojas MJ, Nouzé C, Brodin P, Sebo P, Leclerc C, High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection, Infect. Immun. 2006 Jun;74(6):3396-407.
• 2006
  Beauchamp MC, Lecomte T, Lecomte C, Leclerc C, Corbière M, Do people with a first episode of psychosis differ in personality profiles?, Schizophr. Res. 2006 Jul;85(1-3):162-7.
• 2006
  Rybner-Barnier C, Jacquemot C, Cuche C, Doré G, Majlessi L, Gabellec MM, Moris A, Schwartz O, Di Santo J, Cumano A, Leclerc C, Lazarini F, Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells, J. Virol. 2006 May;80(10):4656-63.
• 2006
  Majlessi L, Simsova M, Jarvis Z, Brodin P, Rojas MJ, Bauche C, Nouzé C, Ladant D, Cole ST, Sebo P, Leclerc C, An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis, Infect. Immun. 2006 Apr;74(4):2128-37.
• 2006
  Mascarell L, Bauche C, Fayolle C, Diop OM, Dupuy M, Nougarede N, Perraut R, Ladant D, Leclerc C, Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates, Vaccine 2006 Apr;24(17):3490-9.
• 2006
  Freire T, Lo-Man R, Piller F, Piller V, Leclerc C, Bay S, Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination, Glycobiology 2006 May;16(5):390-401.
• 2006
  Schlecht G, Mouriès J, Poitrasson-Rivière M, Leclerc C, Dadaglio G, Purification of splenic dendritic cells induces maturation and capacity to stimulate Th1 response in vivo, Int. Immunol. 2006 Mar;18(3):445-52.
• 2006
  Brodin P, Majlessi L, Marsollier L, de Jonge MI, Bottai D, Demangel C, Hinds J, Neyrolles O, Butcher PD, Leclerc C, Cole ST, Brosch R, Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence, Infect. Immun. 2006 Jan;74(1):88-98.
• 2005
  Masin J, Basler M, Knapp O, El-Azami-El-Idrissi M, Maier E, Konopasek I, Benz R, Leclerc C, Sebo P, Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells, Biochemistry 2005 Sep;44(38):12759-66.
• 2005
  Grigalevicius S, Chierici S, Renaudet O, Lo-Man R, Dériaud E, Leclerc C, Dumy P, Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines, Bioconjug. Chem. 2005 Sep-Oct;16(5):1149-59.
• 2005
  Mascarell L, Fayolle C, Bauche C, Ladant D, Leclerc C, Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis, J. Virol. 2005 Aug;79(15):9872-84.
• 2005
  Brodin P, de Jonge MI, Majlessi L, Leclerc C, Nilges M, Cole ST, Brosch R, Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity, J. Biol. Chem. 2005 Oct;280(40):33953-9.
• 2005
  Wilkinson KA, Simsova M, Schölvinck E, Sebo P, Leclerc C, Vordermeier HM, Dickson SJ, Brown JR, Davidson RN, Pasvol G, Levin M, Wilkinson RJ, Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids, Infect. Immun. 2005 May;73(5):2991-8.
• 2005
  Sun CM, Deriaud E, Leclerc C, Lo-Man R, Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs, Immunity 2005 Apr;22(4):467-77.
• 2005
  Boisgérault F, Rueda P, Sun CM, Hervas-Stubbs S, Rojas M, Leclerc C, Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal, J. Immunol. 2005 Mar;174(6):3432-9.
• 2005
  Majlessi L, Brodin P, Brosch R, Rojas MJ, Khun H, Huerre M, Cole ST, Leclerc C, Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system, J. Immunol. 2005 Mar;174(6):3570-9.
• 2005
  Préville X, Ladant D, Timmerman B, Leclerc C, Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein, Cancer Res. 2005 Jan;65(2):641-9.
• 2005
  Lecomte T, Leclerc C, [Group interventions for people with refractory psychosis], Sante Ment Que 2005;30(1):97-115.
• 2004
  Fayolle C, Bauche C, Ladant D, Leclerc C, Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo, Vaccine 2004 Dec;23(5):604-14.
• 2004
  Schlecht G, Loucka J, Najar H, Sebo P, Leclerc C, Antigen targeting to CD11b allows efficient presentation of CD4+ and CD8+ T cell epitopes and in vivo Th1-polarized T cell priming, J. Immunol. 2004 Nov;173(10):6089-97.
• 2004
  Vordermeier HM, Simsova M, Wilkinson KA, Wilkinson RJ, Hewinson RG, Sebo P, Leclerc C, Recognition of mycobacterial antigens delivered by genetically detoxified Bordetella pertussis adenylate cyclase by T cells from cattle with bovine tuberculosis, Infect. Immun. 2004 Nov;72(11):6255-61.
• 2004
  Regner M, Martinez X, Belnoue E, Sun CM, Boisgerault F, Lambert PH, Leclerc C, Siegrist CA, Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres, J. Immunol. 2004 Aug;173(4):2669-74.
• 2004
  Adkins B, Leclerc C, Marshall-Clarke S, Neonatal adaptive immunity comes of age, Nat. Rev. Immunol. 2004 Jul;4(7):553-64.
• 2004
  Vichier-Guerre S, Lo-Man R, Huteau V, Dériaud E, Leclerc C, Bay S, Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen, Bioorg. Med. Chem. Lett. 2004 Jul;14(13):3567-70.
• 2004
  Brodin P, Majlessi L, Brosch R, Smith D, Bancroft G, Clark S, Williams A, Leclerc C, Cole ST, Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens, J. Infect. Dis. 2004 Jul;190(1):115-22.
• 2004
  Schlecht G, Garcia S, Escriou N, Freitas AA, Leclerc C, Dadaglio G, Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation, Blood 2004 Sep;104(6):1808-15.
• 2004
  Simsova M, Sebo P, Leclerc C, The adenylate cyclase toxin from Bordetella pertussis–a novel promising vehicle for antigen delivery to dendritic cells, Int. J. Med. Microbiol. 2004 Apr;293(7-8):571-6.
• 2004
  Demangel C, Brodin P, Cockle PJ, Brosch R, Majlessi L, Leclerc C, Cole ST, Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6, Infect. Immun. 2004 Apr;72(4):2170-6.
• 2004
  Morón G, Dadaglio G, Leclerc C, New tools for antigen delivery to the MHC class I pathway, Trends Immunol. 2004 Feb;25(2):92-7.
• 2003
  Dadaglio G, Morel S, Bauche C, Moukrim Z, Lemonnier FA, Van Den Eynde BJ, Ladant D, Leclerc C, Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes, Int. Immunol. 2003 Dec;15(12):1423-30.
• 2003
  Majlessi L, Rojas MJ, Brodin P, Leclerc C, CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family, Infect. Immun. 2003 Dec;71(12):7173-7.
• 2003
  Haicheur N, Benchetrit F, Amessou M, Leclerc C, Falguières T, Fayolle C, Bismuth E, Fridman WH, Johannes L, Tartour E, The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization, Int. Immunol. 2003 Oct;15(10):1161-71.
• 2003
  Leclerc C, New approaches in vaccine development, Comp. Immunol. Microbiol. Infect. Dis. 2003 Oct;26(5-6):329-41.
• 2003
  Wang F, Jiao XA, Gu J, Ma L, Lo-Man R, Leclerc C, Liu XF, [In-vivo dynamic changes of antigen presenting cells infected with recombinant attenuated Salmonella typhimurium expressing green fluorescent protein], Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003 Sep;19(5):425-7.
• 2003
  Morón VG, Rueda P, Sedlik C, Leclerc C, In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway, J. Immunol. 2003 Sep;171(5):2242-50.
• 2003
  El-Azami-El-Idrissi M, Bauche C, Loucka J, Osicka R, Sebo P, Ladant D, Leclerc C, Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain, J. Biol. Chem. 2003 Oct;278(40):38514-21.
• 2003
  Pym AS, Brodin P, Majlessi L, Brosch R, Demangel C, Williams A, Griffiths KE, Marchal G, Leclerc C, Cole ST, Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis, Nat. Med. 2003 May;9(5):533-9.
• 2003
  Sun CM, Fiette L, Tanguy M, Leclerc C, Lo-Man R, Ontogeny and innate properties of neonatal dendritic cells, Blood 2003 Jul;102(2):585-91.
• 2003
  Jiao X, Lo-Man R, Winter N, Dériaud E, Gicquel B, Leclerc C, The shift of Th1 to Th2 immunodominance associated with the chronicity of Mycobacterium bovis bacille Calmette-Guérin infection does not affect the memory response, J. Immunol. 2003 Feb;170(3):1392-8.
• 2003
  Martinez X, Regner M, Kovarik J, Zarei S, Hauser C, Lambert PH, Leclerc C, Siegrist CA, CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles, Virology 2003 Jan;305(2):428-35.
• 2002
  Guermonprez P, Fayolle C, Rojas MJ, Rescigno M, Ladant D, Leclerc C, In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells., Eur J Immunol 2002 Nov; 32(11): 3071-81.
• 2002
  Boisgérault F, Morón G, Leclerc C, Virus-like particles: a new family of delivery systems, Expert Rev Vaccines 2002 Jun;1(1):101-9.
• 2002
  Ghosh MK, Li CL, Fayolle C, Dadaglio G, Murphy A, Lemonnier FA, Roy P, Leclerc C, Induction of HLA-A2-restricted CTL responses by a tubular structure carrying human melanoma epitopes, Vaccine 2002 Jun;20(19-20):2463-73.
• 2002
  Morón G, Rueda P, Casal I, Leclerc C, CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules, J. Exp. Med. 2002 May;195(10):1233-45.
• 2002
  Moingeon P, Leclerc C, Challenges and issues in new vaccine development, Trends Immunol. 2002 Apr;23(4):173-5.
• 2002
  Dadaglio G, Sun CM, Lo-Man R, Siegrist CA, Leclerc C, Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells, J. Immunol. 2002 Mar;168(5):2219-24.
• 2002
  Loucká J, Schlecht G, Vodolánová J, Leclerc C, Sebo P, Delivery of a MalE CD4(+)-T-cell epitope into the major histocompatibility complex class II antigen presentation pathway by Bordetella pertussis adenylate cyclase, Infect. Immun. 2002 Feb;70(2):1002-5.
• 2002
  Jiao X, Lo-Man R, Guermonprez P, Fiette L, Dériaud E, Burgaud S, Gicquel B, Winter N, Leclerc C, Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity., J Immunol 2002 Feb; 168(3): 1294-301.
• 2002
  Ghosh MK, Dériaud E, Saron MF, Lo-Man R, Henry T, Jiao X, Roy P, Leclerc C, Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences, Vaccine 2002 Jan;20(9-10):1369-77.
• 2000
  Guermonprez P, Fayolle C, Karimova G, Ullmann A, Leclerc C, Ladant D, Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells., Methods Enzymol 2000 ; 326(): 527-42.
• 1999
  Guermonprez P, Lo-Man R, Sedlik C, Rojas MJ, Poljak RJ, Leclerc C, mAb against hen egg-white lysozyme regulate its presentation to CD4(+) T cells., Int Immunol 1999 Nov; 11(11): 1863-72.
• 1999
  Guermonprez P, Ladant D, Karimova G, Ullmann A, Leclerc C, Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway., J Immunol 1999 Feb; 162(4): 1910-6.
• 1998
  Guermonprez P, England P, Bedouelle H, Leclerc C, The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells., J Immunol 1998 Nov; 161(9): 4542-8.