• 2024
  Kamolrat Somboon, Oliver Melling, Maylis Lejeune, Glaucia M S Pinheiro, Annick Paquelin, Benjamin Bardiaux, Michael Nilges, Phillippe Delepelaire, Syma Khalid, Nadia Izadi-Pruneyre, Dynamic interplay between a TonB-dependent heme transporter and a TonB protein in a membrane environment, mBio, In press, pp.e0178124. ⟨10.1128/mbio.01781-24⟩.
• 2024
  Gedeon A, Yab E, Dinut A, Sadowski E, Capton E, Dreneau A, Petit J, Gioia B, Piveteau C, Djaout K, Lecat E, Wehenkel AM, Gubellini F, Mechaly A, Alzari PM, Deprez B, Baulard A, Aubry A, Willand N, Petrella S, Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase., iScience 2024 Oct; 27(10): 110967.
• 2024
  Cristiano da Silva Lameira, Sini Münßinger, Lu Yang, Bernhard Eikmanns, Marco Bellinzoni, Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features, FEBS Journal, In press, ⟨10.1111/febs.17232⟩.
• 2024
  Panei FP, Gkeka P, Bonomi M, Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN., Nat Commun 2024 Jul; 15(1): 5725.
• 2024
  Izadi-Pruneyre, N., Karami, Y., Nilges, M., Structure and Dynamics of Type 4a Pili and Type 2 Secretion System Endopili, In: Macromolecular Protein Complexes V, vol 104. Chapter 21. p549-563.
• 2024
  Alexandra Moine-Franel, Fabien Mareuil, Michael Nilges, Constantin Bogdan Ciambur, Olivier Sperandio, A comprehensive dataset of protein-protein interactions and ligand binding pockets for advancing drug discovery, Scientific Data , 2024, 11 (1), pp.402. ⟨10.1038/s41597-024-03233-z⟩.
• 2024
  Legru A, Batista FA, Puszko AK, Bouillon A, Maurel M, Martinez M, Ejjoummany A, Ortega Varga L, Adler P, Méchaly A, Hadjadj M, Sosnowski P, Hopfgartner G, Alzari PM, Blondel A, Haouz A, Barale JC, Hernandez JF, Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1., Eur J Med Chem 2024 Apr; 269(): 116308.
• 2024
  Perraud V, Vanderhoydonck B, Bouvier G, Dias de Melo G, Kilonda A, Koukni M, Jochmans D, Rogée S, Ben Khalifa Y, Kergoat L, Lannoy J, Van Buyten T, Izadi-Pruneyre N, Chaltin P, Neyts J, Marchand A, Larrous F, Bourhy H, Mechanism of action of phthalazinone derivatives against rabies virus., Antiviral Res 2024 Apr; 224(): 105838.
• 2024
  David Fernandez-Martinez, Youxin Kong, Sylvie Goussard, Agustin Zavala, Pauline Gastineau, Martial Jean-Pierre Rey, Gabriel Ayme, Julia Chamot‐rooke, Pierre Lafaye, Matthijn Vos, Ariel Mechaly, Guillaume Duménil, Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms, Nature Communications, 2024, 15 (1), pp.2414. ⟨10.1038/s41467-024-46677-y⟩.
• 2024
  Martinez M, Bouillon A, Brûlé S, Raynal B, Haouz A, Alzari PM, Barale J-C, Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress., mBio 2024 Mar; 15(3): e0019824.
• 2024
  Hoff SE#, Zinke M#, Izadi-Pruneyre N*, Bonomi M*., Bonds and bytes: The odyssey of structural biology, Curr Opin Struct Biol. 2024 Feb;84:102746. doi: 10.1016/j.sbi.2023.102746. .
• 2024
  Zinke M, Lejeune M, Mechaly A, Bardiaux B, Boneca IG, Delepelaire P, Izadi-Pruneyre N, Ton motor conformational switch and peptidoglycan role in bacterial nutrient uptake., Nat Commun 2024 Jan; 15(1): 331.
• 2024
  Melki J, Kouadio TN, Nowakowski M, Razafiarimanga Z, Soumahoro MK, Peltres S, Jambou R, Production and evaluation of a new set of recombinant antigens for the serological diagnosis of human cysticercosis., Exp Parasitol 2024 ; 263-264(): 108803.
• 2023
  Betancurt-Anzola L, Martínez-Carranza M, Delarue M, Zatopek KM, Gardner AF, Sauguet L, Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases., Nat Commun 2023 Dec; 14(1): 8306.
• 2023
  Guilvout I, Samsudin F, Huber RG, Bond PJ, Bardiaux B, Francetic O, Membrane platform protein PulF of the Klebsiella type II secretion system forms a trimeric ion channel essential for endopilus assembly and protein secretion., mBio 2023 Dec; (): e0142323.
• 2023
  Grasekamp KP, Beaud Benyahia B, Taib N, Audrain B, Bardiaux B, Rossez Y, Izadi-Pruneyre N, Lejeune M, Trivelli X, Chouit Z, Guerardel Y, Ghigo JM, Gribaldo S, Beloin C, The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope bridge for phospholipid trafficking., Nat Commun 2023 Nov; 14(1): 7642.
• 2023
  Meuskens I, Kristiansen PE, Bardiaux B, Koynarev VR, Hatlem D, Prydz K, Lund R, Izadi-Pruneyre N, Linke D, A poly-proline II helix in YadA from Yersinia enterocolitica serotype O:9 facilitates heparin binding through electrostatic interactions., FEBS J 2023 Nov; (): .
• 2023
  Gisele Cardoso de Amorim, Benjamin Bardiaux, Nadia Izadi-Pruneyre, Structural Analysis of Proteins from Bacterial Secretion Systems and Their Assemblies by NMR Spectroscopy, Bacterial Secretion Systems, 2715, Springer US, pp.503-517, 2023, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3445-5_30⟩.
• 2023
  Martinez M, Petit J, Leyva A, Sogues A, Megrian D, Rodriguez A, Gaday Q, Ben Assaya M, Portela MM, Haouz A, Ducret A, Grangeasse C, Alzari PM, Durán R, Wehenkel AM, Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation., Nat Microbiol 2023 Sep; (): .
• 2023
  Yang L, Wagner T, Mechaly A, Boyko A, Bruch EM, Megrian D, Gubellini F, Alzari PM, Bellinzoni M, High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase., Nat Commun 2023 Aug; 14(1): 4851.
• 2023
  Céline Cuche, Marta Mastrogiovanni, Marie Juzans, Hélène Laude, Marie-Noëlle Ungeheuer, Daniel Krentzel, Maria Isabella Gariboldi, Daniel Scott-Algara, Marianne Madec, Sophie Goyard, Camille Floch, Gaëlle Chauveau-Le Friec, Pierre Lafaye, Charlotte Renaudat, Muriel Le Bidan, Christine Micallef, Sandrine Schmutz, Sébastien Mella, Sophie Novault, Milena Hasan, Darragh Duffy, Vincenzo Di Bartolo, Andrés Alcover, T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations, Frontiers in Immunology, 2023, 14, pp.1163466. ⟨10.3389/fimmu.2023.1163466⟩.
• 2023
  Lourenço M, Osbelt L, Passet V, Gravey F, Megrian D, Strowig T, Rodrigues C, Brisse S, Phages against Noncapsulated Klebsiella pneumoniae: Broader Host range, Slower Resistance., Microbiol Spectr 2023 Jun; (): e0481222.
• 2023
  Gedeon A, Ayoub N, Brûlé S, Raynal B, Karimova G, Gelin M, Mechaly A, Haouz A, Labesse G, Munier-Lehmann H, Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs., Protein Sci 2023 Jun; (): e4703.
• 2023
  Li Q, Nemecz Á, Aymé G, Dejean de la Bâtie G, Prevost MS, Pons S, Barilone N, Baachaoui R, Maskos U, Lafaye P, Corringer PJ, Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor., Cell Mol Life Sci 2023 May; 80(6): 164.
• 2023
  Julia Kende, Massimiliano Bonomi, Sarah Temmam, Béatrice Regnault, Philippe Pérot, Marc Eloit, Thomas Bigot, Virus Pop—Expanding Viral Databases by Protein Sequence Simulation, Viruses, 2023, 15 (6), pp.1227. ⟨10.3390/v15061227⟩.
• 2023
  Madru C, Martínez-Carranza M, Laurent S, Alberti AC, Chevreuil M, Raynal B, Haouz A, Le Meur RA, Delarue M, Henneke G, Flament D, Krupovic M, Legrand P, Sauguet L, DNA-binding mechanism and evolution of replication protein A., Nat Commun 2023 Apr; 14(1): 2326.
• 2023
  Schator D, Mondino S, Berthelet J, Di Silvestre C, Ben Assaya M, Rusniok C, Rodrigues-Lima F, Wehenkel A, Buchrieser C, Rolando M, , Legionella para-effectors target chromatin and promote bacterial replication., Nat Commun 2023 Apr; 14(1): 2154.
• 2023
  Sarah Temmam, Xavier Montagutelli, Cécile Herate, Flora Donati, Béatrice Regnault, Mikael Attia, Eduard Baquero Salazar, Delphine Chretien, Laurine Conquet, Grégory Jouvion, Juliana Pipoli da Fonseca, Thomas Cokelaer, Faustine Amara, Francis Relouzat, Thibaut Naninck, Julien Lemaitre, Nathalie Derreudre-Bosquet, Quentin Pascal, Massimiliano Bonomi, Thomas Bigot, Sandie Munier, Felix Rey, Roger Le Grand, Sylvie van der Werf, Marc Eloit, SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19, EMBO Reports, 2023, 24 (4), pp.e56055. ⟨10.15252/embr.202256055⟩.
• 2023
  Proutière A, du Merle L, Garcia-Lopez M, Léger C, Voegele A, Chenal A, Harrington A, Tal-Gan Y, Cokelaer T, Trieu-Cuot P, Dramsi S, , Gallocin A, an Atypical Two-Peptide Bacteriocin with Intramolecular Disulfide Bonds Required for Activity., Microbiol Spectr 2023 Mar; (): e0508522.
• 2023
  Lamon G, Lends A, Valsecchi I, Wong SSW, Duprès V, Lafont F, Tolchard J, Schmitt C, Mallet A, Grélard A, Morvan E, Dufourc EJ, Habenstein B, Guijarro JI, Aimanianda V, Loquet A,, Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition., Proc Natl Acad Sci U S A 2023 Feb; 120(6): e2212003120.
• 2023
  Gedeon A, Karimova G, Ayoub N, Dairou J, Giai Gianetto Q, Vichier-Guerre S, Vidalain PO, Ladant D, Munier-Lehmann H, Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli., FEBS J 2023 Feb; (): .
• 2023
  Dazzoni R, Li Y, López-Castilla A, Brier S, Mechaly A, Cordier F, Haouz A, Nilges M, Francetic O, Bardiaux B, Izadi-Pruneyre N, Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system., Structure 2023 Feb; 31(2): 152-165.e7.
• 2023
  Mourer T, El Ghalid M, Pehau-Arnaudet G, Kauffmann B, Loquet A, Brûlé S, Cabral V, d'Enfert C, Bachellier-Bassi S, The Pga59 cell wall protein is an amyloid forming protein involved in adhesion and biofilm establishment in the pathogenic yeast Candida albicans., NPJ Biofilms Microbiomes 2023 Jan; 9(1): 6.
• 2023
  Liu Z, Valsecchi I, Le Meur RA, Simenel C, Guijarro JI, Comte C, Muszkieta L, Mouyna I, Henrissat B, Aimanianda V, Latgé JP, Fontaine T, Conidium Specific Polysaccharides in Aspergillus fumigatus., J Fungi (Basel) 2023 Jan; 9(2): .
• 2023
  Covaleda-Cortés G, Mechaly A, Brissac T, Baehre H, Devaux L, England P, Raynal B, Hoos S, Gominet M, Firon A, Trieu-Cuot P, Kaminski PA, , The c-di-AMP-binding protein CbpB modulates the level of ppGpp alarmone in Streptococcus agalactiae., FEBS J 2023 Jan; (): .
• 2023
  Giovanna Cesaro, Heloisa Tramontin da Soler, Eloise Pavāo Guerra-Slompo, Ahmed Haouz, Pierre Legrand, Nilson Ivo Tonin Zanchin and Beatriz Gomes Guimaraes, Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates, Nucleic Acids Res . 2023 Jan 11;51(1):380-395. doi: 10.1093/nar/gkac1199..
• 2022
  Ravatin M, Odolczyk N, Servel N, Iñaki Guijarro J, Tagat E, Chevalier B, Baatallah N, Corringer PJ, Lukács GL, Edelman A, Zielenkiewicz P, Chambard JM, Hinzpeter A, Faure G, Design of crotoxin-based peptides with potentiator activity targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator., J Mol Biol 2022 Dec; (): 167929.
• 2022
  Dow LP, Gaietta G, Kaufman Y, Swift MF, Lemos M, Lane K, Hopcroft M, Bezault A, Sauvanet C, Volkmann N, Pruitt BL, Hanein D, , Morphological control enables nanometer-scale dissection of cell-cell signaling complexes., Nat Commun 2022 Dec; 13(1): 7831.
• 2022
  Mairet-Khedim M, Roesch C, Khim N, Srun S, Bouillon A, Kim S, Ke S, Kauy C, Kloeung N, Eam R, Khean C, Kul C, Chy S, Leang R, Ringwald P, Barale JC, Witkowski B, Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia., J Antimicrob Chemother 2022 Dec; (): .
• 2022
  Jacobsen T, Dazzoni R, Renault MG, Bardiaux B, Nilges M, Shevchik V, Izadi-Pruneyre N, , Secondary structure and 1H, 15 N & 13C resonance assignments of the periplasmic domain of OutG, major pseudopilin from Dickeya dadantii type II secretion system., Biomol NMR Assign 2022 Apr; (): .
• 2022
  Valérie Biou, Ricardo Jorge Diogo Adaixo, Mohamed Chami , Pierre-Damien Coureux, Benoist Laurent, Véronique Yvette Ntsogo Enguéné, Gisele Cardoso de Amorim, Nadia Izadi-Pruneyre, Christian Malosse, Julia Chamot-Rooke, Henning Stahlberg, Philippe Delepelaire, Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog, Commun Biol . 2022 Apr 13;5(1):355. .
• 2021
  Dazzoni R, López-Castilla A, Cordier F, Bardiaux B, Nilges M, Francetic O, Izadi-Pruneyre N, , 1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system, Biomol NMR Assign . 2021 Oct;15(2):455-459. .
• 2021
  Karami Y, López-Castilla A, Ori A, Thomassin JL, Bardiaux B, Malliavin T, Izadi-Pruneyre N, Francetic O, Nilges M, Computational and biochemical analysis of type IV pilus dynamics and stability., Structure 2021 Dec; 29(12): 1397-1409.e6.
• 2021
  van Belkum A, Almeida C, Bardiaux B, Barrass SV, Butcher SJ, Çaykara T, Chowdhury S, Datar R, Eastwood I, Goldman A, Goyal M, Happonen L, Izadi-Pruneyre N, Jacobsen T, Johnson PH, Kempf VAJ, Kiessling A, Bueno JL, Malik A, Malmström J, Meuskens I, Milner PA, Nilges M, Pamme N, Peyman SA, Rodrigues LR, Rodriguez-Mateos P, Sande MG, Silva CJ, Stasiak AC, Stehle T, Thibau A, Vaca DJ, Linke D, , Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens., Diagnostics (Basel) 2021 Jul; 11(7): .
• 2019
  Bardiaux B, Cordier F, Brier S, López-Castilla A, Izadi-Pruneyre N, Nilges M, Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches, J. Biomol. NMR 2019 Jul;73(6-7):293-303.
• 2019
  Bardiaux B, de Amorim GC, Luna Rico A, Zheng W, Guilvout I, Jollivet C, Nilges M, Egelman EH, Izadi-Pruneyre N, Francetic O. , Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus., Structure. 2019 Apr 9. doi: 10.1016/j.str.2019.03.021..
• 2018
  Bouvier G, Simenel C, Jang J, Kalia NP, Choi I, Nilges M, Pethe K, Izadi-Pruneyre N. , Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR., Biochemistry. 2019 Feb 12;58(6):526-533. doi: 10.1021/acs.biochem.8b00975. .