Assistant Professor, CR IP (PhD), microbiologist / molecular biologist.
Private: PTR 403 – Generation and validation of innovative tools for 2D- and 3D-real time imaging of trypanosomatid parasites in their mammalian hosts
Trypanosomatidae are a widespread group of flagellated protozoa that cause highly disabling, often fatal, diseases and economic losses in endemic countries. Distinct Trypanosomatidae, transmitted by specific arthropod vectors, can cause human diseases: Trypanosoma (T) […]
Design and optimization of new bioluminescent systems better-suited to in cellulo and in vivo conditions
The use of light from the abyss in biology In the last decades, bioluminescent systems based on the expression of a luciferase and the addition of a luciferin to monitor the emission of […]
Application of IL7-signaling research to guide diagnostic and therapeutic strategies
When the signaling induced by IL-7 is constitutively altered in patients, we observed lymphopenia when the response is reduced (eg AIDS), and leukemia when it is increased (eg acute lymphoblastic leukemia T-ALL). Comparing the […]
Basic Research – IL7 signaling in T-cells
With the technological support of facilities at the Pasteur Institute and through collaborations with several international institutions, we study the early steps of signaling induced by interleukin-7 on CD4 T lymphocytes (helper). This cytokine […]
2012A versatile overexpression strategy in the pathogenic yeast Candida albicans: identification of regulators of morphogenesis and fitness, PLoS ONE 2012;7(9):e45912.
2012Biofilm formation studies in microtiter plate format, Methods Mol. Biol. 2012;845:369-77.
2011Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans, Mol. Microbiol. 2011 May;80(4):995-1013.
2009The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity, Microbiology (Reading, Engl.) 2009 Jun;155(Pt 6):2004-20.
2008The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans, Mol. Biol. Cell 2008 May;19(5):2251-66.
2007The SUN41 and SUN42 genes are essential for cell separation in Candida albicans, Mol. Microbiol. 2007 Dec;66(5):1256-75.
2006Protein O-mannosyltransferase isoforms regulate biofilm formation in Candida albicans, Antimicrob. Agents Chemother. 2006 Oct;50(10):3488-91.
2005Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction, Res. Microbiol. 2005 Aug;156(7):822-9.
2005CandidaDB: a genome database for Candida albicans pathogenomics, Nucleic Acids Res. 2005 Jan;33(Database issue):D353-7.