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Michael Nilges (PI)
A Bayesian Framework for Cellular Structural Biology Objective : “The functioning of a single cell or organism is governed by the laws of chemistry and physics. The bridge from biology to chemistry and physics […]
Michael Nilges (PI)
About Bip:Bip The project Bip:Bip promotes an integrated use of known and modelled three-dimensional structures of proteins as an aid in complete genome annotation. The architectural organization of biological macromolecules is essential for the […]
Bacterial Transmembrane Signaling
Nadia Izadi-Pruneyre (PI)
Bacteria display several mechanisms to adapt to their host-environment and successfully colonise it. One important mechanism of adaptation concerns the regulation of gene expression in response to external signals such as the presence of […]
Integrative Modelling Platform
Riccardo Pellarin (PI)
IMP‘s broad goal is to contribute to a comprehensive structural characterization of biomolecules ranging in size and complexity from small peptides to large macromolecular assemblies, by integrating data from diverse biochemical and biophysical experiments. […]
2019Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling, Structure 27 (2019) 175-188.
2018Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy, Biophys. J. 2018 Apr;114(7):1604-1613.
2018Integrative structure and functional anatomy of a nuclear pore complex, Nature 2018 03;555(7697):475-482.
2018Integrative structure modeling with the Integrative Modeling Platform, Protein Sci. 2018 01;27(1):245-258.
2017Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5, Cell Rep 2017 03;18(11):2651-2663.
2016A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen-Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein-Ligand Interactions, J Phys Chem B 2017 04;121(15):3493-3501.
2016Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform, Volume 167, Issue 5, p1215–1228.e25.
2016Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform, Cell 2016 11;167(5):1215-1228.e25.
2016Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling, Mol. Cell Proteomics 2016 08;15(8):2730-43.
2015Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH, Mol. Cell 2015 Sep;59(5):794-806.
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