I was born in Belgium and obtained my Master degree from the University Pierre et Marie Curie, Paris (France). I completed my PhD studies at the Institut Pasteur, Paris (France) on the regulation of the expression of the central genes of the Escherichia coli PEP-dependent phosphotransferase system. During my postdoctoral fellowship, I moved from fundamental to medical microbiology and studied the control of the expression of the pili of the bacterial pathogen Neisseria gonorrhoeae. Since 1995, I am studying the gastric pathogen Helicobacter pylori. I am currently an Associate Professor at the Institut Pasteur and head of the Helicobacter Pathogenesis group since 2008. From 2014 to 2019, I was director of the Microbiology department of the Institut Pasteur.
Cliquez pour voir le graph
Connexions
Cliquez pour voir la ligne de temps
Ligne de temps
Projets
Anciennes Équipes
CV
Publications
Télécharger-
2023The SlyD metallochaperone targets iron-sulfur biogenesis pathways and the TCA cycle., mBio 2023 Aug; (): e0096723.
-
2022Bacterial Membrane Vesicles as a Novel Strategy for Extrusion of Antimicrobial Bismuth Drug in Helicobacter pylori., mBio 2022 Oct; 13(5): e0163322.
-
2021Small RNA mediated gradual control of lipopolysaccharide biosynthesis affects antibiotic resistance in Helicobacter pylori., Nat Commun 2021 07; 12(1): 4433.
-
2021RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori., Nucleic Acids Res 2021 49:5249-5264.
-
2021A novel mode of control of nickel uptake by a multifunctional metallochaperone., PLoS Pathog 2021 01; 17(1): e1009193.
-
2021Riboregulation in the Major Gastric Pathogen Helicobacter pylori., Front Microbiol 2021 ; 12(): 712804.
-
2020A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral shape to coccoids., Proc Natl Acad Sci U S A 2020 Nov 23:202016195..
-
2020The RNase J-Based RNA Degradosome Is Compartmentalized in the Gastric Pathogen Helicobacter pylori., mBio 2020 Sep; 11(5): .
-
2020Orally administrated chitosan microspheres bind Helicobacter pylori and decrease gastric infection in mice., Acta Biomater 2020 09; 114(): 206-220.
-
2020USF1 defect drives p53 degradation during Helicobacter pylori infection and accelerates gastric carcinogenesis., Gut 2020 09; 69(9): 1582-1591.
-
+Voir la liste complète de publications