(EN)
EDUCATION
- PhD: Institut Curie – INSERM U932 (Paris, France), Immunology – Cell Biology, 2016
- Master/Magistère Européen de Génétique – Université Paris VII (Paris, France), Genetics – Immunology, 2012
RESEARCH EXPERIENCE
- 2017-Now: Institut Pasteur – Pathogenesis of Vascular Infections unit, Dr. Guillaume Duménil, Paris, France – Postdoctral Fellow
- 2012-2016: Institut Curie – INSERM U932, Dr. Ana-Maria Lennon-Duménil, Paris, France – PhD Student
- Ap-Aug 2011: St Jude Children’s Research Hospital, Dr. Peter J. Murray’s lab, Memphis, TN, USA
- June-Aug 2010: Institut Jacques Monod – UMR 7592, Pr. Catherine Alcaïde-Loridan, Paris, France
FELLOWSHIP
- 2018-2020: Pasteur-Roux Postdoctoral Fellowship – Institut Pasteur Paris
- 2015-2016: 4th year PhD Fellowship – Fondation pour la Recherche Médicale
- 2012-2015: PhD Fellowship – Ecole Doctorale BioSPC, Universités Paris V & VII
AWARDS
- 2016: Académie Nationale de Pharmacie, Prix de Thèse en Sciences Biologiques
COMMUNICATIONS
Posters
- 2015: Actin and microtubule cytoskeleton in cell motility and morphogenesis: an integrated view. J. Monod conference, Roscoff, France – “Actin nucleation at the centrosome controls lymphocyte polarity”
- 2013: SFI (French Society of Immunology) annual meeting, Paris, France – “Galectin-8 promotes efficient antigen processing and presentation by B lymphocytes”
- 2012: Current Trends in Biochemistry, Biophysics and Cell Biology, 39th Winter School of Faculty of Biochemistry, Biophysics and Biotechnology, Zakopane, Poland – “Tuning B lymphocyte responses through cell polarity and lysosome exocytosis”
Oral presentations
- 2016: 7th Edition of YRLS (Young Researchers in Life Science) Conference, Paris, France – “Actin nucleation at the centrosome controls lymphocyte polarity”
- 2013: SFI (French Society of Immunology) annual meeting, Paris, France – “Galectin-8 promotes efficient antigen processing and presentation by B lymphocytes”
TEACHING
Invited lecturer
- 2015-2016 & 2016-2017: 2nd year Master’s degree “Biologie Cellulaire, Physiologie et Pathologie, Spécialité Biologie et Développement Cellulaires”, Université Paris Descartes (Paris, France), Course: Membrane dynamics and signaling, Chair: A. Benmerah
- 2012-2013: 3rd year bachelor’s degree, Magistère Européen de Génétique, Université Paris VII (Paris, France), Course: Cell Biology, Chair: C. Alcaïde-Loridan
Teaching assistant
- Jan 2018 & Jan 2019: Master 2 degree, Molecular Biology of the Cell, Institut Pasteur Course, Practical course: Vasculogenesis in microfluidic devices, Chair: C. Zurzolo
- 2014-2015 & 2015-2016: 1st year bachelor’s degree, Université Paris VII – Denis Diderot (Paris, France), Practical course: Molecular biology, Chair: V. Joliot
PUBLICATIONS
- 2018
Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse, Cell Reports, 2018 Dec;25(11):3110-3122.e6.
Vamp-7-dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes, Mol. Biol. Cell, 2017 Apr;28(7):890-897. * equal contribution
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2016
Dynamics of the membrane-cytoskeleton interface in MHC class II-restricted antigen presentation, Immunol. Rev., 2016 Jul;272(1):39-51. All authors equally contributed to this work.
Inflammatory Osteoclasts Prime TNFα-Producing CD4(+) T Cells and Express CX3 CR1, J. Bone Miner. Res., 2016 Oct;31(10):1899-1908
Actin nucleation at the centrosome controls lymphocyte polarity, Nature Communications, 2016 Mar;7:10969.
Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells, Nat. Cell Biol., 2016 Jan;18(1):43-53.
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2015
Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse, Mol. Biol. Cell, 2015 Apr;26(7):1273-85. #, * equal contributions
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2014
A critical role for cell polarity in antigen extraction, processing, and presentation by B lymphocytes, Adv. Immunol., 2014;123:51-67.
- 2012
LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro, BMC Cancer, 2012 Oct;12:455.
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2011
Junctional adhesion molecules are required for melanoma cell lines transendothelial migration in vitro, Pigment Cell Melanoma Res., 2011 Jun;24(3):504-11.