Study of immune crosstalk in COVID-19 COVIMUNE
Our overall goal is to understand the cellular and molecular aspects of immune response to SARS-CoV-2 virus in terms of activation of over-reactive immunity and induction of immune protection. COVIMUNE is designed to target […]
T cell immunity to dengue virus infection in transgenic mice expressing human HLA molecules
Based on the recent identification of the non-structural proteins NS3, NS4B and NS5 of dengue virus (DENV) as the main targets for T cell responses in humans, we have designed a minimal DENV antigen, […]
A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)
The present invention is directed to a Zika virus (ZIKV) chimeric polyepitope composed of fragments of structural and non-structural proteins and its use in an immunogenic composition. The present invention provides means, in particular […]
A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)
The present invention is directed to a dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection. The present invention provides means, in […]
2023Tocilizumab treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants., iScience 2023 Feb; (): 106124.
2019A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice, Front. Immunol. 2019 Jun;10 (1424).
2018Improved Immune Responses Against Zika Virus After Sequential Dengue and Zika Virus Infection in Humans, Viruses 2018 09;10(9).
2018Host genetic control of mosquito-borne Flavivirus infections., Mamm Genome 2018 08; 29(7-8): 384-407.
2018Immune Responses to Dengue and Zika Viruses-Guidance for T Cell Vaccine Development, Int J Environ Res Public Health 2018 02;15(2).
2009Maturation of mouse NK cells is a 4-stage developmental program, Blood 2009 May;113(22):5488-96.
2007Stromal-cell regulation of natural killer cell differentiation, J. Mol. Med. 2007 Oct;85(10):1047-56.
2006Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases, Nat. Immunol. 2006 Jul;7(7):747-54.
2001Identification of committed NK cell progenitors in adult murine bone marrow, Eur. J. Immunol. 2001 Jun;31(6):1900-9.
2000Clonal acquisition of inhibitory Ly49 receptors on developing NK cells is successively restricted and regulated by stromal class I MHC, Immunity 2000 Jul;13(1):143-53.
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