Carbohydrates as targets of immunity: their synthesis, antibody recognition and use as key vaccine components
Synthetic oligosaccharides are designed and used to identify immunodominant epitopes of bacterial polysaccharide antigens. Conjugates of the most promising oligosaccharides are developed as potential vaccines. Focus is on diarrheal diseases. Shigellosis – bacillary […]
Synthetic carbohydrate-based conjugates as Shigella vaccine components: design, synthesis, selection and process validation
2022The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella., ACS Cent Sci 2022 Apr; 8(4): 449-460.
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2008Synthesis of branched tri- to pentasaccharides representative of fragments of Shigella flexneri serotypes 3a and/or X O-antigens, Tetrahedron 2008; 64: 10558-72.
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