
Seminar Joe Bondy-Denomy “A bacteriophage that evades immune nucleases by pretending to be a eukaryote”
Bacteria use front-line defenses like CRISPR-Cas and restriction-modification (R-M) systems to rapidly cleave bacteriophage DNA. However, phages have evolved mechanisms to thwart these systems including anti-CRISPR proteins, anti-RM proteins, DNA modifications, and fascinating nucleus-like […]