A joint 2-year post-doc position to work on a multidisciplinary project dedicated to a biophysical approach of the pathogenicity of Candida albicans is available in the teams “Macromolecules and Microsystems in Biology and Medicine” at Institut Curie, and “Fungal Biology and Pathogenicity Unit” at Institut Pasteur, located in Paris, France. The main aim of the project is to explore the interaction between mammalian cells and Candida albicans hyphae using an organ-on-a-chip approach based on the development of 2D and 3D rigid and soft microenvironments. This approach will be also coupled with theoretical modeling. The position is for 2 years and available immediately. This project is funded by the Institut Pierre-Gilles de Gennes for microfluidics.
The Team “Macromolecules and Microsystems in Biology and Medicine” at Institut Curie has developed a strong expertise in the biophysics of living networks based on a control of cellular microenvironments (including cell positioning, compartmentalization and guidance). The Fungal Biology and Pathogenicity Unit at Institut Pasteur has an extensive knowledge in C. albicans molecular biology and genetics and will provide genome-wide libraries of mutant strains as well as a large collection of sequenced clinical isolates.
Applicants must have completed a PhD with a background in biophysics and/or yeast biology. Candidates should be willing to acquire new knowledge and skills to address this interdisciplinary project. Candidates should be capable to interact with the two labs and organize efficiently his/her agenda on both sites. He/she will have to be creative and rigorous, with the capacity to provide a synthetic description of ongoing work.
If you are interested, please send a letter of motivation, a CV and names from two references to Catherine Villard (catherine.villard@curie.fr) and Christophe d’Enfert (christophe.denfert@pasteur.fr).