Lien vers Pubmed [PMID] – 26407445
Lien DOI – 10.1093/jpids/piv040
J Pediatric Infect Dis Soc 2015 Sep; 4(3): e53-7
A boy with X-linked agammaglobulinemia experienced progressive global motor decline, cerebellar syndrome, and epilepsy. All standard polymerase chain reactions for neurotropic viruses were negative on cerebrospinal fluid and brain biopsy. Next-generation sequencing allowed fast identification of a new astrovirus strain (HAstV-VA1/HMO-C-PA), which led to tailor the patient’s treatment, with encouraging clinical monitoring over 1 year.