Date
20
Sep 2024
Heure
14:00:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Adresse
Bâtiment: 67 Salle: 45
Localisation
2024-09-20 14:00:00
2024-09-20 17:00:00
Europe/Paris
Regulation of IL-23R Expression in Human CD4+ T Cells and the Impact of IL-23 Blockade on Immune Responses in Vivo
This thesis explores the role of Interleukin 23 (IL-23) and its specific receptor (IL-23R) in chronic inflammatory diseases. The research uncovers the regulatory mechanisms of IL-23R expression, the impact of IL-23 in psoriasis, and […]
Institut Pasteur, Rue du Docteur Roux, Paris, France
Lars Rogge
lars.rogge@pasteur.fr
Présentation
This thesis explores the role of Interleukin 23 (IL-23) and its specific receptor (IL-23R) in chronic inflammatory diseases. The research uncovers the regulatory mechanisms of IL-23R expression, the impact of IL-23 in psoriasis, and highlights the complex transcriptional network involved. Findings reveal IL-21’s role in Th17 differentiation, the effects of IL-23 blockade in psoriasis, and the nuanced responses of immune cells to treatment, advancing our understanding of IL-23’s functions in human inflammatory diseases
Localisation
Bâtiment: 67
Salle: 45
Adresse: Institut Pasteur, Rue du Docteur Roux, Paris, France