Timeline

Laurence Dugue
Technician
20 Jun 2019
publication

Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4

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02 Feb 2019
publication

First-in-class allosteric inhibitors of bacterial IMPDHs

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02 Jan 2019
team

Organic Chemistry

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02 Jan 2019
publication

2′-Deoxyribonucleoside 5′-triphosphates bearing 4-phenyl and 4-pyrimidinyl imidazoles as DNA polymerase substrates

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09 Mar 2018
project

Protein synthesis machinery of Trypanosomatid as a therapeutic target

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12 Sep 2017
publication

An expedient synthesis of flexible nucleosides via a regiocontrolled enzymatic glycosylation of functionalized imidazoles

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18 Nov 2016
team

Group : Sylvie Pochet

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11 Mar 2016
publication

Expedient and generic synthesis of imidazole nucleosides by enzymatic transglycosylation

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03 Sep 2015
project

Inhibitors of Pseudomonas aeruginosa IMPDH

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20 Aug 2015
project

Inhibitors of TMPK from Mycobacterium tuberculosis

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28 Jul 2015
project

Inhibitors of bacterial NAD kinases

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11 May 2015
team

Chemistry and Biocatalysis

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12 Nov 2014
publication

A convenient synthesis of 4(5)-(hetero)aryl-1H-imidazoles via microwave-assisted Suzuki-Miyaura cross-coupling reaction

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17 May 2012
publication

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound

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01 Jan 2008
publication

Expanding substrate specificity of nucleoside 2′-deoxyribosyltransferase

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01 May 2002
publication

Synthesis and recognition by DNA polymerases of a reactive nucleoside, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-imidazole-4-hydrazide

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01 Jan 2002
publication

Nucleoside analogues as inhibitors of thymidylate kinases: possible therapeutic applications

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