Timeline
Claudine Mayer
Group Leader
01 Jan 2020
publication
Expanding the type IIB DNA topoisomerase family: identification of new topoisomerase and topoisomerase-like proteins in mobile genetic elements
Read more20 Jan 2016
01 Jan 2016
publication
Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors
Read more28 Jul 2015
project
ATPase inhibitors, the cases of human heat shock protein 90 and bacterial type IIA topoisomerases
Read more15 Oct 2014
publication
Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase
Read more01 Aug 2014
publication
The Molecular Genetics of Fluoroquinolone Resistance in Mycobacterium tuberculosis
Read more02 Jul 2014
publication
DNA topoisomerase VIII: a novel subfamily of type IIB topoisomerases encoded by free or integrated plasmids in Archaea and Bacteria
Read more01 Dec 2013
publication
Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion
Read more01 Nov 2013
06 Jun 2013
publication
The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors
Read more25 May 2013
publication
Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain
Read more30 Jan 2012
publication
Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis
Read more26 Jan 2012
publication
Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase CTD
Read more25 Jan 2012
publication
A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system
Read more18 Jul 2011
publication
DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis
Read more16 Nov 2010
08 Oct 2010
publication
Crl binds to domain 2 of σ(S) and confers a competitive advantage on a natural rpoS mutant of Salmonella enterica serovar Typhi
Read more18 Aug 2010
publication
Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase
Read more30 Oct 2009
publication