Timeline

Claudine Mayer
Group Leader
01 Jan 2020
publication

Expanding the type IIB DNA topoisomerase family: identification of new topoisomerase and topoisomerase-like proteins in mobile genetic elements

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20 Jan 2016
project

MM4TB

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01 Jan 2016
publication

Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors

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08 Oct 2015
project

In solution conformation of the SigmaS subunit of RNA polymerase

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28 Jul 2015
project

ATPase inhibitors, the cases of human heat shock protein 90 and bacterial type IIA topoisomerases

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15 Oct 2014
publication

Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase

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01 Aug 2014
publication

The Molecular Genetics of Fluoroquinolone Resistance in Mycobacterium tuberculosis

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02 Jul 2014
publication

DNA topoisomerase VIII: a novel subfamily of type IIB topoisomerases encoded by free or integrated plasmids in Archaea and Bacteria

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01 Jan 2014
publication

Non-quinolone inhibitors of bacterial type IIA topoisomerases: a feat of bioisosterism

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01 Dec 2013
publication

Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion

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01 Nov 2013
publication

Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes

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06 Jun 2013
publication

The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors

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25 May 2013
publication

Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain

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30 Jan 2012
publication

Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis

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26 Jan 2012
publication

Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase CTD

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25 Jan 2012
publication

A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system

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18 Jul 2011
publication

DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis

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16 Nov 2010
publication

Conformational transition of DNA bound to Hfq probed by infrared spectroscopy

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08 Oct 2010
publication

Crl binds to domain 2 of σ(S) and confers a competitive advantage on a natural rpoS mutant of Salmonella enterica serovar Typhi

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18 Aug 2010
publication

Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase

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30 Oct 2009
publication

Purification, crystallization and preliminary X-ray diffraction experiments on the breakage-reunion domain of the DNA gyrase from Mycobacterium tuberculosis

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