Timeline

Benoit Chassaing
Head of Structure
17 Dec 2024
project

Facteurs environnementaux et alimentaires impliqués dans la régulation du microbiote-ENVIMIC

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18 Nov 2024
project

Le microbiote intestinal détermine une réponse personnalisée aux avantages métaboliques médiés par Akkermansia muciniphila-AmucMet

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24 Oct 2024
event

PhD defense : Modern diet-induced microbiota alterations: impact on diseases susceptibility and transgenerational effects – Clara Delaroque

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24 Oct 2024
news

Annual Day of Microb’UP Institute 2025 – January 8th, 2025 – Odeon site

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01 Jun 2024
publication

Ultra-processed foods and food additives in gut health and disease.

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01 May 2024
publication

Food additive emulsifiers and the risk of type 2 diabetes: analysis of data from the NutriNet-Santé prospective cohort study.

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01 May 2024
publication

Effects of a Cycling versus Running HIIT Program on Fat Mass Loss and Gut Microbiota Composition in Men with Overweight/Obesity.

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25 Apr 2024
team

Microbiome-Host Interactions

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01 Apr 2024
publication

Vitamin D and prebiotics for intestinal health in cystic fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 x 2 trial of administration of prebiotics and cholecalciferol (vitamin D3) (Pre-D trial) in adults with cystic fibrosis.

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01 Feb 2024
publication

Food additive emulsifiers and cancer risk: Results from the French prospective NutriNet-Santé cohort.

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06 Jan 2024
publication

Dietary emulsifier consumption accelerates type 1 diabetes development in NOD mice.

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05 Jan 2024
publication

Individualized microbiotas dictate the impact of dietary fiber on colitis sensitivity.

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01 Jan 2024
publication

Human Intestinal Microbiome Determines Individualized Inflammatory Response to Dietary Emulsifier Carboxymethylcellulose Consumption.

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01 Jan 2024
publication

Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity enhances susceptibility to colonic inflammation.

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01 Jan 2024
publication

Dietary Amino Acid Source Elicits Sex-Specific Metabolic Response to Diet-Induced NAFLD in Mice.

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01 Jan 2024
publication

A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice.

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09 Dec 2023
publication

Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption.

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08 Dec 2023
publication

Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle.

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01 Dec 2023
publication

Microbiome differences related to metformin intolerance among Black individuals with diabetes, a pilot cross-sectional study.

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22 Sep 2023
publication

Perinatal Morphine Exposure Induces Long-Term Changes in the Intestinal Microbiota of Male and Female Rats.

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15 Sep 2023
publication

Obesity promotes fumonisin B1 hepatotoxicity.

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06 Sep 2023
publication

Food additive emulsifiers and risk of cardiovascular disease in the NutriNet-Santé cohort: prospective cohort study.

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01 Sep 2023
publication

Vaccination against microbiota motility protects mice from the detrimental impact of dietary emulsifier consumption.

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01 Sep 2023
publication

Author Correction: Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.

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25 Aug 2023
publication

Regulation of Lung Immune Tone by the Gut-Lung Axis via Dietary Fiber, Gut Microbiota, and Short-Chain Fatty Acids.

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13 Jul 2023
publication

A 90-day oral exposure to food-grade gold at relevant human doses impacts the gut microbiota and the local immune system in a sex-dependent manner in mice.

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01 Jul 2023
publication

Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.

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01 May 2023
publication

Akkermansia muciniphila counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism.

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01 Jan 2023
publication

Comparing Transgenic Production to Supplementation of ω-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders.

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01 Jan 2023
publication

Probiotic: is diet part of the efficacy equation?

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01 Jan 2023
publication

Mirroring Amino Acids Hold Sway to Scare Pathobionts Away.

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01 Jan 2023
publication

Brain effects of gestating germ-free persist in mouse neonates despite acquisition of a microbiota at birth.

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01 Jan 2023
publication

Psyllium Fiber Protects Against Colitis Via Activation of Bile Acid Sensor Farnesoid X Receptor.

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01 Dec 2022
publication

Ultra-processed foods and human health: from epidemiological evidence to mechanistic insights.

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23 Nov 2022
publication

Dietary Emulsifiers Exacerbate Food Allergy and Colonic Type 2 Immune Response through Microbiota Modulation.

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12 Oct 2022
publication

When NOD ligands become antidotes.

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01 Sep 2022
publication

Reply.

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07 Aug 2022
publication

Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation.

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01 Aug 2022
publication

MiniBioReactor Array (MBRA) in vitro gut model: a reliable system to study microbiota-dependent response to antibiotic treatment.

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28 Jul 2022
publication

Dietary Inulin Supplementation Affects Specific Plasmalogen Species in the Brain.

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26 Jul 2022
publication

Local Delivery of Streptomycin in Microcontainers Facilitates Colonization of Streptomycin-Resistant Escherichia coli in the Rat Colon.

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01 Jun 2022
publication

Dietary emulsifier consumption alters gene expression in the amygdala and paraventricular nucleus of the hypothalamus in mice.

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24 May 2022
publication

Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn’s Disease.

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01 Apr 2022
publication

Gut Barrier Dysfunction and Type 2 Immunity: Implications for Compulsive Behavior.

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01 Mar 2022
publication

Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome.

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01 Mar 2022
publication

Effect of Concurrent Training on Body Composition and Gut Microbiota in Postmenopausal Women with Overweight or Obesity.

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01 Feb 2022
publication

Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity.

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20 Jan 2022
team

U1306 – Host-Microbe interactions and pathophysiology

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01 Jan 2022
publication

Diet standardization reduces intra-individual microbiome variation.

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01 Jan 2022
publication

[Food emulsifiers and intestinal microbiota: beware of your muffin!].

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01 Jan 2022
publication

Connecting the Dots: Dietary Fat, Microbiota Dysbiosis, Altered Metabolome, and Colon Cancer.

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01 Jan 2022
publication

The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.

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01 Jan 2022
publication

A Microbiota-Dependent Response to Anticancer Treatment in an In Vitro Human Microbiota Model: A Pilot Study With Hydroxycarbamide and Daunorubicin.

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01 Sep 2021
publication

Host/microbiota interactions in health and diseases-Time for mucosal microbiology!

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01 Sep 2021
publication

Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases.

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22 Jun 2021
publication

Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease.

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01 Jun 2021
publication

Dietary fat and low fiber in purified diets differently impact the gut-liver axis to promote obesity-linked metabolic impairments.

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07 May 2021
publication

The TOTUM-63 Supplement and High-Intensity Interval Training Combination Limits Weight Gain, Improves Glycemic Control, and Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a High Fat Diet.

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23 Apr 2021
publication

Critical Role of Innate Immunity to Flagellin in the Absence of Adaptive Immunity.

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21 Apr 2021
publication

Beneficial Effects of Natural Mineral Waters on Intestinal Inflammation and the Mucosa-Associated Microbiota.

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23 Mar 2021
publication

Soluble Fiber Inulin Consumption Limits Alterations of the Gut Microbiota and Hepatic Fatty Acid Metabolism Caused by High-Fat Diet.

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22 Mar 2021
publication

Direct impact of commonly used dietary emulsifiers on human gut microbiota.

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05 Mar 2021
publication

Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma.

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27 Feb 2021
publication

High-Intensity Interval Training and α-Linolenic Acid Supplementation Improve DHA Conversion and Increase the Abundance of Gut Mucosa-Associated Oscillospira Bacteria.

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12 Feb 2021
publication

Ingestion of probiotic (Lactobacillus helveticus and Bifidobacterium longum) alters intestinal microbial structure and behavioral expression following social defeat stress.

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13 Jan 2021
publication

The Intestinal Microbiota: Our Best Frenemy in Radiation-Induced Damages?

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01 Jan 2021
publication

The postnatal window is critical for the development of sex-specific metabolic and gut microbiota outcomes in offspring.

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01 Jan 2021
publication

When Pathobiont-Carbohydrate Interaction Turns Bittersweet!

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01 Jan 2021
publication

Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis.

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01 Jan 2021
publication

Inulin Fermentable Fiber Ameliorates Type I Diabetes via IL22 and Short-Chain Fatty Acids in Experimental Models.

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01 Jan 2021
publication

First Encounters: Effects of the Microbiota on Neonatal Brain Development.

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01 Jan 2021
publication

Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia.

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06 Oct 2020
publication

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation.

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02 Oct 2020
publication

IL-22-induced cell extrusion and IL-18-induced cell death prevent and cure rotavirus infection.

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15 Sep 2020
publication

Emulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn’s Disease.

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01 Aug 2020
publication

Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice.

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21 Jul 2020
publication

Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations.

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01 Jul 2020
publication

Impact of a high-fat diet on the fatty acid composition of the retina.

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04 Jun 2020
publication

Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats.

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01 Apr 2020
publication

Commensal epitopes drive differentiation of colonic Tregs.

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10 Feb 2020
publication

Enhanced E. coli LF82 Translocation through the Follicle-associated Epithelium in Crohn’s Disease is Dependent on Long Polar Fimbriae and CEACAM6 expression, and Increases Paracellular Permeability.

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01 Feb 2020
publication

Organ-level protein networks as a reference for the host effects of the microbiome.

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24 Jan 2020
publication

Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration.

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07 Jan 2020
publication

Prognostic value of a combination of innovative factors (gut microbiota, sarcopenia, obesity, metabolic syndrome) to predict surgical/oncologic outcomes following surgery for sporadic colorectal cancer: a prospective cohort study protocol (METABIOTE).

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01 Jan 2020
publication

The Hidden Effect of Nod2 in the Host/Microbiota Relationship.

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01 Jan 2020
publication

“Western Diet”-Induced Adipose Inflammation Requires a Complex Gut Microbiota.

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01 Jan 2020
publication

[Vaccination approach against chronic inflammatory diseases?].

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11 Dec 2019
publication

Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases.

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01 Dec 2019
publication

Amelioration of metabolic syndrome by metformin associates with reduced indices of low-grade inflammation independently of the gut microbiota.

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27 Nov 2019
publication

The intestinal microbiota regulates host cholesterol homeostasis.

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13 Nov 2019
publication

A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection.

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17 Oct 2019
publication

Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection.

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01 Oct 2019
publication

Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation.

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01 Sep 2019
publication

Associations of the Fecal Microbial Proteome Composition and Proneness to Diet-induced Obesity.

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01 Sep 2019
publication

Experimental models to study intestinal microbes-mucus interactions in health and disease.

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01 Feb 2019
publication

[Inulin: the beauty and the beast].

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17 Jan 2019
publication

Dietary emulsifiers consumption alters anxiety-like and social-related behaviors in mice in a sex-dependent manner.

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01 Jan 2019
publication

Identification of Inner Mucus-Associated Bacteria by Laser Capture Microdissection.

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01 Jan 2019
publication

Host-derived fecal microRNAs can indicate gut microbiota healthiness and ability to induce inflammation.

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01 Jan 2019
publication

Maltodextrin, Modern Stressor of the Intestinal Environment.

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01 Jan 2019
publication

Chronic Inflammatory Diseases: Are We Ready for Microbiota-based Dietary Intervention?

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01 Dec 2018
publication

Considerations for best practices in studies of fiber or other dietary components and the intestinal microbiome.

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01 Nov 2018
publication

Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

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18 Oct 2018
publication

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.

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01 Aug 2018
publication

Impact of food additives on the gut-brain axis.

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01 Aug 2018
publication

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

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01 May 2018
publication

Toxin-positive Clostridium difficile latently infect mouse colonies and protect against highly pathogenic C. difficile.

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01 Mar 2018
publication

Insights on the impact of diet-mediated microbiota alterations on immunity and diseases.

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13 Feb 2018
publication

First victim, later aggressor: How the intestinal microbiota drives the pro-inflammatory effects of dietary emulsifiers?

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10 Jan 2018
publication

Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health.

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02 Jan 2018
publication

Vasopressin deletion is associated with sex-specific shifts in the gut microbiome.

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01 Jan 2018
publication

Role of vitamin D on gut microbiota in cystic fibrosis.

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01 Jan 2018
publication

Mice harboring pathobiont-free microbiota do not develop intestinal inflammation that normally results from an innate immune deficiency.

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01 Jan 2018
publication

The microbiota influences cell death and microglial colonization in the perinatal mouse brain.

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01 Nov 2017
publication

How diet can impact gut microbiota to promote or endanger health.

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01 Sep 2017
publication

Colonic Microbiota Encroachment Correlates With Dysglycemia in Humans.

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01 Aug 2017
publication

Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation.

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01 Jul 2017
publication

Supplementation of Low- and High-fat Diets with Fermentable Fiber Exacerbates Severity of DSS-induced Acute Colitis.

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01 Jul 2017
publication

Ectopic Expression of Innate Immune Protein, Lipocalin-2, in Lactococcus lactis Protects Against Gut and Environmental Stressors.

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06 Apr 2017
publication

Genome Sequence of a Toxin-Positive Clostridium difficile Strain Isolated from Murine Feces.

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20 Mar 2017
publication

Enterohemorrhagic Escherichia coli pathogenesis: role of Long polar fimbriae in Peyer’s patches interactions.

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01 Mar 2017
publication

Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling.

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06 Feb 2017
publication

Tryptophan: A gut microbiota-derived metabolites regulating inflammation.

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01 Jan 2017
publication

Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis.

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05 Nov 2016
publication

When pathogenic bacteria meet the intestinal microbiota

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01 Nov 2016
publication

Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa.

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01 Sep 2016
publication

Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease.

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11 Aug 2016
publication

Corrigendum: Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

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01 Jul 2016
publication

Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis.

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01 Jul 2016
publication

Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria.

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01 Jul 2016
publication

Microbiota Alterations in Inflammatory Bowel Diseases: From Correlation to Causality.

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01 Jun 2016
publication

Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics.

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01 May 2016
publication

Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment.

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01 May 2016
publication

Intestinal dysbiosis contributes to the delayed gastrointestinal transit in high-fat diet fed mice.

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12 Feb 2016
publication

Policing of gut microbiota by the adaptive immune system.

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01 Feb 2016
publication

Has provoking microbiota aggression driven the obesity epidemic?

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01 Jan 2016
publication

GipA Factor Supports Colonization of Peyer’s Patches by Crohn’s Disease-associated Escherichia Coli.

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01 Jan 2016
publication

Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage.

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01 Dec 2015
publication

Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.

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01 Oct 2015
publication

Lack of soluble fiber drives diet-induced adiposity in mice.

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01 Aug 2015
publication

Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium.

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01 May 2015
publication

MyD88-mediated TLR signaling protects against acute rotavirus infection while inflammasome cytokines direct Ab response.

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01 Apr 2015
publication

[The intestinal microbiota helps shapping the adaptive immune response against viruses].

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01 Apr 2015
publication

Analysis of the σE regulon in Crohn’s disease-associated Escherichia coli revealed involvement of the waaWVL operon in biofilm formation.

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05 Mar 2015
publication

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

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01 Jan 2015
publication

[Involvement of food additives in intestinal inflammation and metabolic syndrome in mice].

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15 Dec 2014
publication

Glaser oxidative coupling on peptides: Stabilization of β-turn structure via a 1,3-butadiyne constraint.

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01 Dec 2014
publication

Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice.

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01 Dec 2014
publication

Pathobiont hypnotises enterocytes to promote tumour development.

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01 Dec 2014
publication

Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome’s potential to cause inflammation.

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14 Nov 2014
publication

Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18.

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01 Nov 2014
publication

In Memoriam, Arlette Darfeuille-Michaud, PhD.

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01 Nov 2014
publication

In Memoriam, Arlette Darfeuille-Michaud, PhD.

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18 Sep 2014
publication

TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination.

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15 Jul 2014
publication

Antibiotic treatment suppresses rotavirus infection and enhances specific humoral immunity.

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01 Jul 2014
publication

AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition.

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04 Feb 2014
publication

Dextran sulfate sodium (DSS)-induced colitis in mice.

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01 Jan 2014
publication

Mammalian gut immunity.

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01 Jan 2014
publication

Gut microbiota, low-grade inflammation, and metabolic syndrome.

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01 Jan 2014
publication

Microbiota-liver axis in hepatic disease.

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13 Nov 2013
publication

Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut.

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01 Apr 2013
publication

Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.

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01 Feb 2013
publication

Bile salts induce long polar fimbriae expression favouring Crohn’s disease-associated adherent-invasive Escherichia coli interaction with Peyer’s patches.

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01 Jan 2013
publication

The σE pathway is involved in biofilm formation by Crohn’s disease-associated adherent-invasive Escherichia coli.

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16 Aug 2012
publication

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice.

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15 Aug 2012
publication

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.

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01 Jan 2012
publication

Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.

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01 Jan 2012
publication

Gut microbiota drives metabolic disease in immunologically altered mice.

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01 May 2011
publication

The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases.

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01 Mar 2011
publication

Crohn disease–associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae.

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01 Jan 2011
publication

[The interaction of Crohn’s disease-associated Escherichia coli to Peyer’s patches of the intestinal mucosa involves long polar fimbriae].

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01 Jan 2011
publication

Interactions with M cells and macrophages as key steps in the pathogenesis of enterohemorrhagic Escherichia coli infections.

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