Timeline
Benoit Chassaing
Head of Structure
17 Dec 2024
project
Facteurs environnementaux et alimentaires impliqués dans la régulation du microbiote-ENVIMIC
Read more18 Nov 2024
project
Le microbiote intestinal détermine une réponse personnalisée aux avantages métaboliques médiés par Akkermansia muciniphila-AmucMet
Read more24 Oct 2024
event
PhD defense : Modern diet-induced microbiota alterations: impact on diseases susceptibility and transgenerational effects – Clara Delaroque
Read more24 Oct 2024
01 Jun 2024
01 May 2024
publication
Food additive emulsifiers and the risk of type 2 diabetes: analysis of data from the NutriNet-Santé prospective cohort study.
Read more01 May 2024
publication
Effects of a Cycling versus Running HIIT Program on Fat Mass Loss and Gut Microbiota Composition in Men with Overweight/Obesity.
Read more25 Apr 2024
01 Apr 2024
publication
Vitamin D and prebiotics for intestinal health in cystic fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 x 2 trial of administration of prebiotics and cholecalciferol (vitamin D3) (Pre-D trial) in adults with cystic fibrosis.
Read more01 Feb 2024
publication
Food additive emulsifiers and cancer risk: Results from the French prospective NutriNet-Santé cohort.
Read more06 Jan 2024
publication
Dietary emulsifier consumption accelerates type 1 diabetes development in NOD mice.
Read more05 Jan 2024
publication
Individualized microbiotas dictate the impact of dietary fiber on colitis sensitivity.
Read more01 Jan 2024
publication
Human Intestinal Microbiome Determines Individualized Inflammatory Response to Dietary Emulsifier Carboxymethylcellulose Consumption.
Read more01 Jan 2024
publication
Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity enhances susceptibility to colonic inflammation.
Read more01 Jan 2024
publication
Dietary Amino Acid Source Elicits Sex-Specific Metabolic Response to Diet-Induced NAFLD in Mice.
Read more01 Jan 2024
publication
A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice.
Read more09 Dec 2023
publication
Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption.
Read more08 Dec 2023
publication
Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle.
Read more01 Dec 2023
publication
Microbiome differences related to metformin intolerance among Black individuals with diabetes, a pilot cross-sectional study.
Read more22 Sep 2023
publication
Perinatal Morphine Exposure Induces Long-Term Changes in the Intestinal Microbiota of Male and Female Rats.
Read more15 Sep 2023
06 Sep 2023
publication
Food additive emulsifiers and risk of cardiovascular disease in the NutriNet-Santé cohort: prospective cohort study.
Read more01 Sep 2023
publication
Vaccination against microbiota motility protects mice from the detrimental impact of dietary emulsifier consumption.
Read more01 Sep 2023
publication
Author Correction: Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.
Read more25 Aug 2023
publication
Regulation of Lung Immune Tone by the Gut-Lung Axis via Dietary Fiber, Gut Microbiota, and Short-Chain Fatty Acids.
Read more13 Jul 2023
publication
A 90-day oral exposure to food-grade gold at relevant human doses impacts the gut microbiota and the local immune system in a sex-dependent manner in mice.
Read more01 Jul 2023
publication
Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling.
Read more01 May 2023
publication
Akkermansia muciniphila counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism.
Read more01 Jan 2023
publication
Comparing Transgenic Production to Supplementation of ω-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders.
Read more01 Jan 2023
01 Jan 2023
01 Jan 2023
publication
Brain effects of gestating germ-free persist in mouse neonates despite acquisition of a microbiota at birth.
Read more01 Jan 2023
publication
Psyllium Fiber Protects Against Colitis Via Activation of Bile Acid Sensor Farnesoid X Receptor.
Read more01 Dec 2022
publication
Ultra-processed foods and human health: from epidemiological evidence to mechanistic insights.
Read more23 Nov 2022
publication
Dietary Emulsifiers Exacerbate Food Allergy and Colonic Type 2 Immune Response through Microbiota Modulation.
Read more12 Oct 2022
01 Sep 2022
07 Aug 2022
publication
Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation.
Read more01 Aug 2022
publication
MiniBioReactor Array (MBRA) in vitro gut model: a reliable system to study microbiota-dependent response to antibiotic treatment.
Read more28 Jul 2022
publication
Dietary Inulin Supplementation Affects Specific Plasmalogen Species in the Brain.
Read more26 Jul 2022
publication
Local Delivery of Streptomycin in Microcontainers Facilitates Colonization of Streptomycin-Resistant Escherichia coli in the Rat Colon.
Read more01 Jun 2022
publication
Dietary emulsifier consumption alters gene expression in the amygdala and paraventricular nucleus of the hypothalamus in mice.
Read more24 May 2022
publication
Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn’s Disease.
Read more01 Apr 2022
publication
Gut Barrier Dysfunction and Type 2 Immunity: Implications for Compulsive Behavior.
Read more01 Mar 2022
publication
Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome.
Read more01 Mar 2022
publication
Effect of Concurrent Training on Body Composition and Gut Microbiota in Postmenopausal Women with Overweight or Obesity.
Read more01 Feb 2022
publication
Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity.
Read more20 Jan 2022
01 Jan 2022
01 Jan 2022
01 Jan 2022
publication
Connecting the Dots: Dietary Fat, Microbiota Dysbiosis, Altered Metabolome, and Colon Cancer.
Read more01 Jan 2022
publication
The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.
Read more01 Jan 2022
publication
A Microbiota-Dependent Response to Anticancer Treatment in an In Vitro Human Microbiota Model: A Pilot Study With Hydroxycarbamide and Daunorubicin.
Read more01 Sep 2021
publication
Host/microbiota interactions in health and diseases-Time for mucosal microbiology!
Read more01 Sep 2021
publication
Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases.
Read more22 Jun 2021
publication
Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease.
Read more01 Jun 2021
publication
Dietary fat and low fiber in purified diets differently impact the gut-liver axis to promote obesity-linked metabolic impairments.
Read more07 May 2021
publication
The TOTUM-63 Supplement and High-Intensity Interval Training Combination Limits Weight Gain, Improves Glycemic Control, and Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a High Fat Diet.
Read more23 Apr 2021
publication
Critical Role of Innate Immunity to Flagellin in the Absence of Adaptive Immunity.
Read more21 Apr 2021
publication
Beneficial Effects of Natural Mineral Waters on Intestinal Inflammation and the Mucosa-Associated Microbiota.
Read more23 Mar 2021
publication
Soluble Fiber Inulin Consumption Limits Alterations of the Gut Microbiota and Hepatic Fatty Acid Metabolism Caused by High-Fat Diet.
Read more22 Mar 2021
05 Mar 2021
publication
Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma.
Read more27 Feb 2021
publication
High-Intensity Interval Training and α-Linolenic Acid Supplementation Improve DHA Conversion and Increase the Abundance of Gut Mucosa-Associated Oscillospira Bacteria.
Read more12 Feb 2021
publication
Ingestion of probiotic (Lactobacillus helveticus and Bifidobacterium longum) alters intestinal microbial structure and behavioral expression following social defeat stress.
Read more13 Jan 2021
01 Jan 2021
publication
The postnatal window is critical for the development of sex-specific metabolic and gut microbiota outcomes in offspring.
Read more01 Jan 2021
01 Jan 2021
01 Jan 2021
publication
Inulin Fermentable Fiber Ameliorates Type I Diabetes via IL22 and Short-Chain Fatty Acids in Experimental Models.
Read more01 Jan 2021
01 Jan 2021
publication
Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia.
Read more06 Oct 2020
publication
Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation.
Read more02 Oct 2020
publication
IL-22-induced cell extrusion and IL-18-induced cell death prevent and cure rotavirus infection.
Read more15 Sep 2020
publication
Emulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn’s Disease.
Read more01 Aug 2020
publication
Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice.
Read more21 Jul 2020
publication
Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations.
Read more01 Jul 2020
04 Jun 2020
publication
Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats.
Read more01 Apr 2020
10 Feb 2020
publication
Enhanced E. coli LF82 Translocation through the Follicle-associated Epithelium in Crohn’s Disease is Dependent on Long Polar Fimbriae and CEACAM6 expression, and Increases Paracellular Permeability.
Read more01 Feb 2020
publication
Organ-level protein networks as a reference for the host effects of the microbiome.
Read more24 Jan 2020
publication
Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration.
Read more07 Jan 2020
publication
Prognostic value of a combination of innovative factors (gut microbiota, sarcopenia, obesity, metabolic syndrome) to predict surgical/oncologic outcomes following surgery for sporadic colorectal cancer: a prospective cohort study protocol (METABIOTE).
Read more01 Jan 2020
01 Jan 2020
publication
“Western Diet”-Induced Adipose Inflammation Requires a Complex Gut Microbiota.
Read more01 Jan 2020
11 Dec 2019
publication
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases.
Read more01 Dec 2019
publication
Amelioration of metabolic syndrome by metformin associates with reduced indices of low-grade inflammation independently of the gut microbiota.
Read more27 Nov 2019
13 Nov 2019
publication
A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection.
Read more17 Oct 2019
01 Oct 2019
publication
Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation.
Read more01 Sep 2019
publication
Associations of the Fecal Microbial Proteome Composition and Proneness to Diet-induced Obesity.
Read more01 Sep 2019
publication
Experimental models to study intestinal microbes-mucus interactions in health and disease.
Read more01 Feb 2019
17 Jan 2019
publication
Dietary emulsifiers consumption alters anxiety-like and social-related behaviors in mice in a sex-dependent manner.
Read more01 Jan 2019
publication
Identification of Inner Mucus-Associated Bacteria by Laser Capture Microdissection.
Read more01 Jan 2019
publication
Host-derived fecal microRNAs can indicate gut microbiota healthiness and ability to induce inflammation.
Read more01 Jan 2019
01 Jan 2019
publication
Chronic Inflammatory Diseases: Are We Ready for Microbiota-based Dietary Intervention?
Read more01 Dec 2018
publication
Considerations for best practices in studies of fiber or other dietary components and the intestinal microbiome.
Read more01 Nov 2018
publication
Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
Read more18 Oct 2018
publication
Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.
Read more01 Aug 2018
01 Aug 2018
publication
Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
Read more01 May 2018
publication
Toxin-positive Clostridium difficile latently infect mouse colonies and protect against highly pathogenic C. difficile.
Read more01 Mar 2018
publication
Insights on the impact of diet-mediated microbiota alterations on immunity and diseases.
Read more13 Feb 2018
publication
First victim, later aggressor: How the intestinal microbiota drives the pro-inflammatory effects of dietary emulsifiers?
Read more10 Jan 2018
publication
Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health.
Read more02 Jan 2018
publication
Vasopressin deletion is associated with sex-specific shifts in the gut microbiome.
Read more01 Jan 2018
01 Jan 2018
publication
Mice harboring pathobiont-free microbiota do not develop intestinal inflammation that normally results from an innate immune deficiency.
Read more01 Jan 2018
publication
The microbiota influences cell death and microglial colonization in the perinatal mouse brain.
Read more01 Nov 2017
01 Sep 2017
01 Aug 2017
publication
Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation.
Read more01 Jul 2017
publication
Supplementation of Low- and High-fat Diets with Fermentable Fiber Exacerbates Severity of DSS-induced Acute Colitis.
Read more01 Jul 2017
publication
Ectopic Expression of Innate Immune Protein, Lipocalin-2, in Lactococcus lactis Protects Against Gut and Environmental Stressors.
Read more06 Apr 2017
publication
Genome Sequence of a Toxin-Positive Clostridium difficile Strain Isolated from Murine Feces.
Read more20 Mar 2017
publication
Enterohemorrhagic Escherichia coli pathogenesis: role of Long polar fimbriae in Peyer’s patches interactions.
Read more01 Mar 2017
publication
Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling.
Read more06 Feb 2017
01 Jan 2017
publication
Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis.
Read more05 Nov 2016
01 Nov 2016
publication
Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa.
Read more01 Sep 2016
publication
Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease.
Read more11 Aug 2016
publication
Corrigendum: Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.
Read more01 Jul 2016
publication
Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis.
Read more01 Jul 2016
publication
Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria.
Read more01 Jul 2016
publication
Microbiota Alterations in Inflammatory Bowel Diseases: From Correlation to Causality.
Read more01 Jun 2016
publication
Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics.
Read more01 May 2016
publication
Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment.
Read more01 May 2016
publication
Intestinal dysbiosis contributes to the delayed gastrointestinal transit in high-fat diet fed mice.
Read more12 Feb 2016
01 Feb 2016
01 Jan 2016
publication
GipA Factor Supports Colonization of Peyer’s Patches by Crohn’s Disease-associated Escherichia Coli.
Read more01 Jan 2016
01 Dec 2015
publication
Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.
Read more01 Oct 2015
01 Aug 2015
publication
Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium.
Read more01 May 2015
publication
MyD88-mediated TLR signaling protects against acute rotavirus infection while inflammasome cytokines direct Ab response.
Read more01 Apr 2015
publication
[The intestinal microbiota helps shapping the adaptive immune response against viruses].
Read more01 Apr 2015
publication
Analysis of the σE regulon in Crohn’s disease-associated Escherichia coli revealed involvement of the waaWVL operon in biofilm formation.
Read more05 Mar 2015
publication
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.
Read more01 Jan 2015
publication
[Involvement of food additives in intestinal inflammation and metabolic syndrome in mice].
Read more15 Dec 2014
publication
Glaser oxidative coupling on peptides: Stabilization of β-turn structure via a 1,3-butadiyne constraint.
Read more01 Dec 2014
publication
Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice.
Read more01 Dec 2014
01 Dec 2014
publication
Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome’s potential to cause inflammation.
Read more14 Nov 2014
publication
Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18.
Read more01 Nov 2014
01 Nov 2014
18 Sep 2014
publication
TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination.
Read more15 Jul 2014
publication
Antibiotic treatment suppresses rotavirus infection and enhances specific humoral immunity.
Read more01 Jul 2014
publication
AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition.
Read more04 Feb 2014
01 Jan 2014
01 Jan 2014
01 Jan 2014
13 Nov 2013
publication
Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut.
Read more01 Apr 2013
publication
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.
Read more01 Feb 2013
publication
Bile salts induce long polar fimbriae expression favouring Crohn’s disease-associated adherent-invasive Escherichia coli interaction with Peyer’s patches.
Read more01 Jan 2013
publication
The σE pathway is involved in biofilm formation by Crohn’s disease-associated adherent-invasive Escherichia coli.
Read more16 Aug 2012
publication
Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice.
Read more15 Aug 2012
publication
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
Read more01 Jan 2012
publication
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.
Read more01 Jan 2012
01 May 2011
publication
The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases.
Read more01 Mar 2011
publication
Crohn disease–associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae.
Read more01 Jan 2011
publication
[The interaction of Crohn’s disease-associated Escherichia coli to Peyer’s patches of the intestinal mucosa involves long polar fimbriae].
Read more01 Jan 2011
publication