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member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Search

Triplex formation on DNA targets: how to choose the oligonucleotide

Biochemistry

Vekhoff P, Ceccaldi A, Polverari D, Pylouster J, Pisano C, Arimondo PB

The triple helix: 50 years later, the outcome

Nucleic acids research

Duca M, Vekhoff P, Oussedik K, Halby L, Arimondo PB

Targeting MDR1 gene: synthesis and cellular study of modified daunomycin-triplex-forming oligonucleotide conjugates able to inhibit gene expression in resistant cell lines

Molecular pharmacology

Stierlé V, Duca M, Halby L, Senamaud-Beaufort C, Capobianco ML, Laigle A, Jollès B, Arimondo PB

Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence

Nucleic acids research

Koster DA, Czerwinski F, Halby L, Crut A, Vekhoff P, Palle K, Arimondo PB, Dekker NH

HU binds and folds single-stranded DNA

Nucleic acids research

Kamashev D, Balandina A, Mazur AK, Arimondo PB, Rouviere-Yaniv J

“DNA, more than just a ladder”. A tribute to Michel Duguet (1943-2005)

Biochimie

Rossignol JM, Jacquet M, Arimondo PB

Thirty years of Escherichia coli DNA gyrase: from in vivo function to single-molecule mechanism

Biochimie

Nöllmann M, Crisona NJ, Arimondo PB

Topoisomerase action on short DNA duplexes reveals requirements for gate and transfer DNA segments

The Journal of biological chemistry

Belotserkovskii BP, Arimondo PB, Cozzarelli NR

Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides

Nucleic acids research

Duca M, Guianvarc'h D, Oussedik K, Halby L, Garbesi A, Dauzonne D, Monneret C, Osheroff N, Giovannangeli C, Arimondo PB

Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds

European journal of medicinal chemistry

Guillaumel J, Léonce S, Pierré A, Renard P, Pfeiffer B, Arimondo PB, Monneret C

Exploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates

Molecular and cellular biology

Arimondo PB, Thomas CJ, Oussedik K, Baldeyrou B, Mahieu C, Halby L, Guianvarc'h D, Lansiaux A, Hecht SM, Bailly C, Giovannangeli C

Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties

Bioconjugate chemistry

Duca M, Oussedik K, Ceccaldi A, Halby L, Guianvarc'h D, Dauzonne D, Monneret C, Sun JS, Arimondo PB

Activation of camptothecin derivatives by conjugation to triple helix-forming oligonucleotides

Biochemistry

Arimondo PB, Laco GS, Thomas CJ, Halby L, Pez D, Schmitt P, Boutorine A, Garestier T, Pommier Y, Hecht SM, Sun JS, Bailly C

Novel carbamate derivatives of 4-beta-amino-4′-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation

Organic & biomolecular chemistry

Duca M, Arimondo PB, Léonce S, Pierré A, Pfeiffer B, Monneret C, Dauzonne D

Synthesis and biological study of a new series of 4′-demethylepipodophyllotoxin derivatives

Journal of medicinal chemistry

Duca M, Guianvarc'h D, Meresse P, Bertounesque E, Dauzonne D, Kraus-Berthier L, Thirot S, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C

Position- and orientation-specific enhancement of topoisomerase I cleavage complexes by triplex DNA structures

Nucleic acids research

Antony S, Arimondo PB, Sun JS, Pommier Y

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Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

Calls

Application as permanent staff scientist at Institut Pasteur

The Institut Pasteur is looking for a Scientific Director

Call for proposals | Grant: Auditory Infection and/or Immunity

Call for applications 2025 – Creation of new research groups at the Institut Pasteur

Events

3 Upcoming Events

Calendar

Today

23 Dec 2024

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Department of Parasites and Insect Vectors Extraordinary Seminar : Systems Immunology at Spatial Resolution: AI-Driven Insights into Infectious Diseases”

Epigenetic Chemical Biology

Impact of foetal CMV infection on the developing brain and inner ear – Pierre GRESSENS

Epigenetic Chemical Biology

First international conference on CK1 PROTEIN KINASES: “FROM CELL SIGNALING TO THERAPEUTIC TARGETS IN HUMAN DISEASE” – Lorenzo Pinna, David Virshup , Nagi G Ayad , Kathy Gould , Nicolas Thomä , Carrie Partch , Stephanie Federico, Yinon Ben-Neriah , David Strutt , Stefan Knapp , Nicole Robbins , Volker Dötsch

Epigenetic Chemical Biology

Jobs

Post-doctoral position at Institut Pasteur in Paris

Translational Immunology

Job: Research Engineer

Bioinformatic engineer position at Institut Pasteur, Paris

Dendritic cells and adaptive immunity

Job: Research Engineer

Data manager/curator for genomic taxonomies of bacterial strains (12-month CDD)

Data Management Core Facility

Postdoctoral position in the “Immunobiology and Therapy” Unit

Immunobiology and Therapy

Network

Publications

Nature communications

Multilateral benefit-sharing from digital sequence information will support both science and biodiversity conservation.

Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells.

Mucosal immunology

Animal and translational models of SARS-CoV-2 infection and COVID-19.

Analytical chemistry

Advanced In Vivo Cross-Linking Mass Spectrometry Platform to Characterize Proteome-Wide Protein Interactions.

News

The paper by Thomas Serrano, Stéphane Frémont, Frédérique Cuvelier and Arnaud Echar...

The paper by Thomas Serrano, Stéphane Frémont, Frédérique Cuvelier and Arnaud Echar...

Amazed project

The paper by Korenkova et al, (2024) was commented on in the journal Nature