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© Research
Publication : Cell

Wrapping up stereocilia rootlets

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell - 28 May 2010

Boutet de Monvel J, Petit C

Link to Pubmed [PMID] – 20510920

Cell 2010 May;141(5):748-50

The actin-filled stereocilia of cochlear hair cells deflect in response to sound by pivoting around rootlets at their insertion points at the sensory cell surface. Kitajiri et al. (2010) now show that the actin-binding protein TRIOBP tightly bundles the actin filaments into rootlets, endowing these stereocilia “pivots” with unique elasticity and robustness.

http://www.ncbi.nlm.nih.gov/pubmed/20510920