Wrapping up stereocilia rootlets - Research - Institut Pasteur

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The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias

The 33 carboxyl-terminal residues of Spa40 orchestrate the multi-step assembly process of the type III secretion needle complex in Shigella flexneri

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Published in Cell - 28 May 2010

Boutet de Monvel J, Petit C

Link to Pubmed [PMID] – 20510920

Cell 2010 May;141(5):748-50

The actin-filled stereocilia of cochlear hair cells deflect in response to sound by pivoting around rootlets at their insertion points at the sensory cell surface. Kitajiri et al. (2010) now show that the actin-binding protein TRIOBP tightly bundles the actin filaments into rootlets, endowing these stereocilia “pivots” with unique elasticity and robustness.

Published on: 28 May 2010