Whole genome sequencing and phylogenetic characterization of a novel bat-associated picornavirus-like virus with an unusual genome organization

Link to Pubmed [PMID] – 31785365

Link to HAL – inrae-03732025

Link to DOI – 10.1016/j.meegid.2019.104130

Infection, Genetics and Evolution, 2020, 78, 5 p. ⟨10.1016/j.meegid.2019.104130⟩

The order Picornavirales is one of the most important viral orders in terms of virus diversity and genome organizations, ranging from a mono- or bi-cistronic expression strategies to the recently described poly-cistronic Polycipiviridae viruses. We report here the description and characterization of a novel picorna-like virus identified in rectal swabs of frugivorous bats in Cambodia that presents an unusual genome organization. Kandabadicivirus presents a unique genome architecture and distant phylogenetic relationship to the proposed Badiciviridae family. These findings highlight a high mosaicism of genome organizations among the Picornavirales.