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© Research
Publication : Nature cell biology

When you are Dishevelled, fat is good and acid is bad!

Team: Dynamics of Developmental Decisions in Drosophila
Member: François Schweisguth
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Nature cell biology - 01 Mar 2009

Schweisguth F

Link to Pubmed [PMID] – 19255568

Nat. Cell Biol. 2009 Mar;11(3):237-9

Frizzled receptors regulate cell fate decisions and planar cell polarity by means of distinct intracellular effectors. The choice between these two signalling outputs may involve a pH-dependent interaction between Dishevelled and negatively charged lipids at the plasma membrane.