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© Research
Publication : Transplant infectious disease : an official journal of the Transplantation Society

Unusual presentation of chromoblastomycosis due to Cladophialophora carrionii in a renal and pancreas transplant recipient patient successfully treated with posaconazole and surgical excision

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Transplant infectious disease : an official journal of the Transplantation Society - 07 Dec 2009

Dupont C, Duong TA, Mallet S, Mamzer-Bruneel MF, Thervet E, Bougnoux ME, Dupont B

Link to Pubmed [PMID] – 20002358

Transpl Infect Dis 2010 Apr;12(2):180-3

Chromoblastomycosis is a chronic, tropical and subtropical, subcutaneous mycosis caused by inoculation of dematiaceous molds. This disease is uncommonly reported in patients who have undergone solid organ transplantation. We describe a case of chromoblastomycosis caused by Cladophialophora carrionii that occurred 7 years after transplantation in a 58-year-old male renal and pancreatic transplant recipient. Diagnosis was based on histopathology and isolation of multiple colonies of the dematiaceous mold in pure culture. Identification was achieved by sequencing of the internal transcribed spacer regions of the rRNA. The patient was successfully treated with posaconazole and surgical excision of a residual lesion.