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© Tessa Quax, David Prangishvili, Gerard Pehau-Arnaudet, Jean-Marc Panaud
VAPs (virus-associated pyramids) formed by the Sulfolobus islandicus rod-shaped virus 2 (SIRV2) in cells of its hyperthermophilic archaeal host. Negative contrast electron micrography.
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of virology - 11 Dec 2013

Krupovic M, Quemin ER, Bamford DH, Forterre P, Prangishvili D

Link to Pubmed [PMID] – 24335300

J. Virol. 2014 Feb;88(4):2354-8

Viruses with spindle-shaped virions are abundant in diverse environments. Over the years, such viruses have been isolated from a wide range of archaeal hosts. Evolutionary relationships between them remained enigmatic, however. Here, using structural proteins as markers, we define familial ties among these “dark horses” of the virosphere and segregate all spindle-shaped viruses into two distinct evolutionary lineages, corresponding to Bicaudaviridae and Fuselloviridae. Our results illuminate the utility of structure-based virus classification and bring additional order to the virosphere.

http://www.ncbi.nlm.nih.gov/pubmed/24335300