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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Journal of biology

The bacterial pathogen Listeria monocytogenes: an emerging model in prokaryotic transcriptomics

Team: Bacteria-Cell Interactions
Member: Pascale Cossart
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of biology - 30 Dec 2009

Cossart P, Archambaud C

Link to Pubmed [PMID] – 20053304

J. Biol. 2009;8(12):107

A major challenge in bacterial pathogenesis is understanding the molecular basis of the switch from saprophytism to virulence. Following a recent whole-genome transcriptomic analysis using tiling arrays, an article published in BMC Genomics reports the first use of RNA-seq in Listeria monocytogenes in order to identify genes controlled by sigma B, a transcriptional regulator with a critical role in virulence.