Shigella Stays on the Move | Research

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Structure of the calcium-dependent type 2 secretion pseudopilus

The chromosomal organization of horizontal gene transfer in bacteria

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Diseases

Organisms

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Technique

Published in Cell host & microbe - 11 Oct 2017

Lopez-Montero N, Enninga J

Link to Pubmed [PMID] – 29024638

Cell Host Microbe 2017 Oct;22(4):432-433

Guanylate-binding proteins (GBPs) confer protection against intracellular pathogens. In this issue of Cell Host & Microbe, Wandel et al. (2017) report that cytosolic Shigella becomes trapped within a GBP coat that prevents bacterial cell-to-cell spread. However, this defense mechanism is counteracted by the bacterial E3 ubiquitin ligase IpaH9.8.

Published on: 11 Oct 2017