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© Research
Publication : Current biology : CB

Regulation of notch signaling activity

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current biology : CB - 01 Feb 2004

Schweisguth F

Link to Pubmed [PMID] – 14986688

Curr. Biol. 2004 Feb;14(3):R129-38

Cell-cell signalling mediated by the receptor Notch is used widely across the metazoans to determine cell fate and regulate pattern formation. Notch signals via a conserved regulated intramembrane proteolysis. Recent analyses of the cell biology of the Notch receptor have identified several fundamental mechanisms that contribute to regulate Notch signaling activity in space and time.

http://www.ncbi.nlm.nih.gov/pubmed/14986688