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© Research
Publication : Current biology : CB

Regulation of notch signaling activity

Team: Dynamics of Developmental Decisions in Drosophila
Member: François Schweisguth
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current biology : CB - 01 Feb 2004

Schweisguth F

Link to Pubmed [PMID] – 14986688

Curr. Biol. 2004 Feb;14(3):R129-38

Cell-cell signalling mediated by the receptor Notch is used widely across the metazoans to determine cell fate and regulate pattern formation. Notch signals via a conserved regulated intramembrane proteolysis. Recent analyses of the cell biology of the Notch receptor have identified several fundamental mechanisms that contribute to regulate Notch signaling activity in space and time.