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© Research
Publication : Applied and environmental microbiology

Phylogenetic and functional analysis of Aspergillus fumigatus MGTC, a fungal protein homologous to a bacterial virulence factor

Team: Archived: Aspergillus
Team: Evolutionary Biology of the Microbial Cell
Team: Archived: Molecular Biology of Gene in Extremophiles
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Applied and environmental microbiology - 20 May 2011

Gastebois A, Blanc Potard AB, Gribaldo S, Beau R, Latgé JP, Mouyna I

Link to Pubmed [PMID] – 21602378

Appl. Environ. Microbiol. 2011 Jul;77(13):4700-3

MgtC is important for the survival of several bacterial pathogens in macrophages and for growth under magnesium limitation. Among eukaryotes, a gene homologous to mgtC was found only in the pathogenic fungus Aspergillus fumigatus. Our data show that the A. fumigatus MgtC (AfuMgtC) protein does not have the same function as the bacterial MgtC proteins.