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  • Undergraduate Student
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  • Director of Center
  • Director of Department
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© Research
Publication : Nucleic acids research

Phospho.ELM: a database of phosphorylation sites–update 2008

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Nucleic acids research - 25 Oct 2007

Diella F, Gould CM, Chica C, Via A, Gibson TJ

Link to Pubmed [PMID] – 17962309

Nucleic Acids Res. 2008 Jan;36(Database issue):D240-4

Phospho.ELM is a manually curated database of eukaryotic phosphorylation sites. The resource includes data collected from published literature as well as high-throughput data sets. The current release of Phospho.ELM (version 7.0, July 2007) contains 4078 phospho-protein sequences covering 12 025 phospho-serine, 2362 phospho-threonine and 2083 phospho-tyrosine sites. The entries provide information about the phosphorylated proteins and the exact position of known phosphorylated instances, the kinases responsible for the modification (where known) and links to bibliographic references. The database entries have hyperlinks to easily access further information from UniProt, PubMed, SMART, ELM, MSD as well as links to the protein interaction databases MINT and STRING. A new BLAST search tool, complementary to retrieval by keyword and UniProt accession number, allows users to submit a protein query (by sequence or UniProt accession) to search against the curated data set of phosphorylated peptides. Phospho.ELM is available on line at: http://phospho.elm.eu.org.