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© Research
Publication : Expert review of vaccines

Other Bordetellas, lessons for and from pertussis vaccines

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Expert review of vaccines - 18 Jul 2014

Guiso N, Hegerle N

Link to Pubmed [PMID] – 25034039

Expert Rev Vaccines 2014 Sep;13(9):1125-33

The Bordetella genus comprises nine species of which Bordetella pertussis and B. parapertussis are isolated from humans and are the most studied Bordetella species since they cause whooping cough. They both originate from B. bronchiseptica, which infects several mammals and immune compromised humans, but the intensive use of pertussis vaccines induced changes in B. pertussis and B. parapertussis populations. B. petrii and B. holmesii are other species of unknown reservoir and transmission pattern that have been described in humans. It is still unknown whether these species are pathogens for humans or only opportunistic bacteria but biological diagnosis has confirmed the presence of B. holmesii in human respiratory samples while B. petrii and the four other species have little implications for public health.

http://www.ncbi.nlm.nih.gov/pubmed/25034039