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© Research
Publication : Journal of medical microbiology

Occurrence of IMP-1 in non-baumannii Acinetobacter clinical isolates from Brazil.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of medical microbiology - 01 May 2018

Cayô R, Streling AP, Nodari CS, Matos AP, de Paula Luz A, Dijkshoorn L, Pignatari ACC, Gales AC,

Link to Pubmed [PMID] – 29624159

Link to DOI – 10.1099/jmm.0.000732

J Med Microbiol 2018 May; 67(5): 628-630

The aim of this study was to characterize the presence of carbapenemase-encoding genes in distinct species of Acinetobacter spp. isolated from Brazilian hospitals. Five carbapenem-resistant Acinetobacter spp. isolates (two Acinetobacter pittii, two Acinetobacter bereziniae and one Acinetobacter junii) recovered from two distinct hospitals between 2000 and 2016 were included in this study. All of the isolates harboured blaIMP-1, which was inserted into In86, a class 1 integron. Pulsed field gel eletrophoresis analysis showed that both A. pittii were identical, while the two A. berezinae isolates were considered to be clonally related. In this study, we demonstrated that mobile elements carrying carbapenemase-encoding genes such as In86 may persist for a long period, allowing their mobilization from A. baumannii to other Acinetobacter spp. that are usually susceptible to multiple antimicrobials.

https://pubmed.ncbi.nlm.nih.gov/29624159