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© Christelle Durand
Microscopie d'un neurone. Le marquage jaune montre les synapses.
Publication : BMC medical genetics

Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controls

Team: Human Genetics and Cognitive Functions
Member: Thomas Bourgeron
Member: Richard Delorme
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BMC medical genetics - 05 Jul 2010

Delorme R, Betancur C, Scheid I, Anckarsäter H, Chaste P, Jamain S, Schuroff F, Nygren G, Herbrecht E, Dumaine A, Mouren MC, Råstam M, Leboyer M, Gillberg C, Bourgeron T

Link to Pubmed [PMID] – 20602773

BMC Med. Genet. 2010;11:108

The gene encoding carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase (NOS1AP) is located on chromosome 1q23.3, a candidate region for schizophrenia, autism spectrum disorders (ASD) and obsessive-compulsive disorder (OCD). Previous genetic and functional studies explored the role of NOS1AP in these psychiatric conditions, but only a limited number explored the sequence variability of NOS1AP.