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© Carmen Buchrieser, Marie-Christine Prevost
Legionella pneumophila et son flagelle, bactérie responsable de pneumopathie aigue grave. Bactérie de l'environnement , l'émergence récente de cette maladie s'explique par son affinité pour les systèmes modernes d'alimentation en eau comme les tours de refroidissement. Image colorisée.
Publication : Trends in microbiology

Legionella Effectors Explored with INSeq: New Functional Insights

Team: Biology Of Intracellular Bacteria
Member: Monica Rolando
Member: Carmen Buchrieser
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in microbiology - 30 Jan 2018

Rolando M, Buchrieser C

Link to Pubmed [PMID] – 29395730

Trends Microbiol. 2018 Jan;

Legionella pneumophila secretes over 300 effector proteins that manipulate host cells. This multiplicity of effectors hampers the characterization of their individual roles. Shames et al. report a new approach to solve the enigma of Legionella effector function by using INSeq to analyse effector functions in the context of infection.