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© Research
Publication : Microbes and infection / Institut Pasteur

Invasion and intracellular trafficking of Brucella abortus in nonphagocytic cells

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Microbes and infection / Institut Pasteur - 01 Jun 2000

Pizarro-Cerdá J, Moreno E, Gorvel JP

Link to Pubmed [PMID] – 10955964

Microbes Infect. 2000 Jun;2(7):829-35

Brucella abortus is a facultative intracellular parasite that promotes its own internalization in nonphagocytic cells. The bacterium initially interacts with compartments of the early endocytic cascade, then rapidly segregates from this intracellular pathway and associates with the autophagocytic cascade. During the late stages of infection, Brucella proliferates within the endoplasmic reticulum of host cells.

http://www.ncbi.nlm.nih.gov/pubmed/10955964