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© Research
Publication : Clinical & translational immunology

Interleukin-22 in urinary tract disease – new experimental directions.

Team: Mucosal Inflammation and Immunity
Member: Molly Ingersoll
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Clinical & translational immunology - 01 Jan 2020

Ingersoll MA, Starkey MR,

Link to Pubmed [PMID] – 32523694

Link to DOI – 10.1002/cti2.1143

Clin Transl Immunology 2020 ; 9(6): e1143

Interleukin (IL)-22 is expressed by immune cells in the urinary tract and IL-22 receptor is expressed in urothelium and renal tubule cells. IL-22 can be specifically targeted in the urinary tract or conditionally depleted in mice and targeted therapeutically in humans.