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© A-M. Pais-Correia, M-I. Thoulouze, A. Alcover, A. Gessain
Mise en évidence de structures de type "biofilm ", formées par le rétrovirus HTLV-1 générés par des cellules infectées (cellules du haut), qui ont été transmis à un autre lymphocyte (cellule du bas). Micrographie en microscopie électronique à balayage. Image colorisée.
Publication : Memorias do Instituto Oswaldo Cruz

Influence of age on the haemoglobin concentration of malaria-infected patients in a reference centre in the Brazilian Amazon.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Memorias do Instituto Oswaldo Cruz - 01 Aug 2014

Siqueira AM, Cavalcante JA, Vítor-Silva S, Reyes-Lecca RC, Alencar AC, Monteiro WM, Alexandre MA, Mourão MP, Guinovart C, Bassat Q, Alecrim Md, Lacerda MV,

Link to Pubmed [PMID] – 25141283

Link to DOI – S0074-02762014005040132

Mem Inst Oswaldo Cruz 2014 Aug; 109(5): 569-76

Anaemia is amongst the major complications of malaria, a major public health problem in the Amazon Region in Latin America. We examined the haemoglobin (Hb) concentrations of malaria-infected patients and compared it to that of malaria-negative febrile patients and afebrile controls. The haematological parameters of febrile patients who had a thick-blood-smear performed at an infectious diseases reference centre of the Brazilian Amazon between December 2009-January 2012 were retrieved together with clinical data. An afebrile community control group was composed from a survey performed in a malaria-endemic area. Hb concentrations and anaemia prevalence were analysed according to clinical-epidemiological status and demographic characteristics. In total, 7,831 observations were included. Patients with Plasmodium falciparum infection had lower mean Hb concentrations (10.5 g/dL) followed by P. vivax-infected individuals (12.4 g/dL), community controls (12.8 g/dL) and malaria-negative febrile patients (13.1 g/dL) (p < 0.001). Age, gender and clinical-epidemiological status were strong independent predictors for both outcomes. Amongst malaria-infected individuals, women in the reproductive age had considerably lower Hb concentrations. In this moderate transmission intensity setting, both vivax and falciparum malaria are associated with reduced Hb concentrations and risk of anaemia throughout a wide age range.

https://pubmed.ncbi.nlm.nih.gov/25141283