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© Research
Publication : Gene

IFNA2: The prototypic human alpha interferon

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Gene - 14 May 2015

Paul F, Pellegrini S, Uzé G

Link to Pubmed [PMID] – 25982860

Gene 2015 Aug;567(2):132-137

The human interferon α2 (IFNα2) was the first highly active IFN subtype to be cloned in the early eighties. It was also the first IFN and the first cytokine to be produced and commercialized by the pharmaceutical industry. Ipso facto it became the favorite IFNα subtype for academic researchers. For this fortunate reason IFNα2 has been at the origin of most discoveries related to the mechanism of action of type I interferons.

http://www.ncbi.nlm.nih.gov/pubmed/25982860