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© Research
Publication : The American journal of tropical medicine and hygiene

Household-based sero-epidemiologic survey after a yellow fever epidemic, Sudan, 2005

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The American journal of tropical medicine and hygiene - 01 Jun 2010

Farnon EC, Gould LH, Griffith KS, Osman MS, Kholy AE, Brair ME, Panella AJ, Kosoy O, Laven JJ, Godsey MS, Perea W, Hayes EB

Link to Pubmed [PMID] – 20519615

Am. J. Trop. Med. Hyg. 2010 Jun;82(6):1146-52

From September through early December 2005, an outbreak of yellow fever (YF) occurred in South Kordofan, Sudan, resulting in a mass YF vaccination campaign. In late December 2005, we conducted a serosurvey to assess YF vaccine coverage and to better define the epidemiology of the outbreak in an index village. Of 552 persons enrolled, 95% reported recent YF vaccination, and 25% reported febrile illness during the outbreak period: 13% reported YF-like illness, 4% reported severe YF-like illness, and 12% reported chikungunya-like illness. Of 87 persons who provided blood samples, all had positive YF serologic results, including three who had never been vaccinated. There was also serologic evidence of recent or prior chikungunya virus, dengue virus, West Nile virus, and Sindbis virus infections. These results indicate that YF virus and chikungunya virus contributed to the outbreak. The high prevalence of YF antibody among vaccinees indicates that vaccination was effectively implemented in this remotely located population.