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© Valérie Zeitoun
Stéthoscope. Centre Médical de l'Institut Pasteur (CMIP).
Publication : Travel medicine and infectious disease

Hepatitis B screening in travelers: a retrospective analysis

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Travel medicine and infectious disease - 17 Jul 2014

Gergely A, Bechet S, Goujon C, Benabdelmoumen G, Consigny PH

Link to Pubmed [PMID] – 25086491

Travel Med Infect Dis 2014 Nov-Dec;12(6 Pt B):707-12

BACKGROUND: Non-immune travelers are at risk of acquiring hepatitis B (HB) in high prevalence countries.

METHOD: At the Institut Pasteur Vaccination Center in a retrospective study we retrieved hepatitis B serological data from the vaccination database between 2008 and 2012. Serology (HBsAg, HBsAb and HBcAb) is proposed to travelers who have no information about their previous HB vaccination status if they travel to countries of high or intermediate prevalence of HB, for long or frequent trips.

RESULTS: Of 1093 people 53.1% were men, mean age was 39.6 ± 13.0 years. Prevalence of chronic HBV infection was 5.86% (64 subjects). Their mean age was 36.2 ± 7.3 years, 65.6% were men. Seroprevalence of people of sub-Saharan African origin was 9.2%, higher than the other geographic groups. Past, resolved HB infection was found in 320 subjects, 29.3% of the population; 90.3% were of sub-Saharan African origin. A subgroup of the “Past, resolved HB infection”: 73 people (6.7% of the population) had isolated HB core antibodies. Vaccine induced immunity was found in 286 subjects (26.17% of the total population), 40% of people born in France. All three markers of HB were negative at 38.7% of our total population (423 people), and 54% of people of French origin.

CONCLUSIONS: HB seroprevalence was higher than in general French and European population, due to our large number of individuals with immigrant background. Pre-travel counseling allows screening and vaccination of non-immune travelers and detection of chronic HB infection cases.

https://www.ncbi.nlm.nih.gov/pubmed/25086491