Link to Pubmed [PMID] – 34657789
Link to DOI – S0968-0004(21)00223-110.1016/j.tibs.2021.10.002
Trends Biochem Sci 2022 Jan; 47(1): 3-5
Giant viruses have extravagantly large double-stranded (ds)DNA genomes that are packaged into exceedingly complex virions. In two recent papers, Liu et al. and Valencia-Sánchez, Abini-Agbomson et al. show that some giant viruses encode unique histone doublets, which form nucleosomes remarkably similar to those found across the eukaryotic domain of life.