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© Research
Publication : BMC systems biology

Evolution of metabolic network organization

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BMC systems biology - 11 May 2010

Mazurie A, Bonchev D, Schwikowski B, Buck GA

Link to Pubmed [PMID] – 20459825

BMC Syst Biol 2010;4:59

Comparison of metabolic networks across species is a key to understanding how evolutionary pressures shape these networks. By selecting taxa representative of different lineages or lifestyles and using a comprehensive set of descriptors of the structure and complexity of their metabolic networks, one can highlight both qualitative and quantitative differences in the metabolic organization of species subject to distinct evolutionary paths or environmental constraints.

http://www.ncbi.nlm.nih.gov/pubmed/20459825