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© Research
Publication : Microbes and infection / Institut Pasteur

Do DNA microarrays have their future behind them?

Team: Biomics
Member: Jean-Yves Coppee
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Microbes and infection / Institut Pasteur - 09 Jul 2008

Coppée JY

Link to Pubmed [PMID] – 18662797

Microbes Infect. 2008 Jul;10(9):1067-71

The first report on DNA microarray technology appeared in Science in 1995. Starting from gene expression profiling, its application fields have considerably evolved and extend from microbiology to cancer study. DNA microarrays are now routinely used for the detection of single nucleotide polymorphisms, microRNAs analysis, study of copy number variation, CpG methylations detection…. Furthermore, the approval of DNA microarray technology by US Food and Drug Administration has opened the door to new applications in clinical diagnostics. At the same time, DNA arrays have to face the concurrence of the latest generation of very high throughput sequencing devices which are predicted to make the microarray technology obsolete. This review will discuss on this paradoxical situation.