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© Research
Publication : Current opinion in immunology

Distinguishing features of developing natural killer cells

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current opinion in immunology - 01 Apr 2005

Vosshenrich CA, Samson-Villéger SI, Di Santo JP

Link to Pubmed [PMID] – 15766674

Curr. Opin. Immunol. 2005 Apr;17(2):151-8

Although NK cells were initially described as lymphocytes that lacked the characteristic markers of B and T cells, we now appreciate the plethora of activating and inhibitory receptors that define the NK cell surface phenotype. Recent studies have provided new insights into the molecular mechanisms that drive NK cell development, control the NK cell receptor repertoire and the cytokines that define the NK cell niche. These findings form the basis for an updated model of NK cell differentiation.

http://www.ncbi.nlm.nih.gov/pubmed/15766674